1.
Fiziol Zh SSSR Im I M Sechenova
; 73(10): 1425-9, 1987 Oct.
Artigo
em Russo
| MEDLINE
| ID: mdl-2828125
RESUMO
The relationships between cAMP and hyaluronate hydrolases (HH) activity were studied in the renal tissue. Both the urine osmolality and the HH activity were increased in the papilla tissue of rats treated with cAMP. Incubation of mild homogenized cells prepared from kidney papilla with cAMP, resulted in a significant increase in the total HH activity and that of beta-glucuronidase and N-acetyl-beta-D-hexosaminidase, whereas the activity of hyaluronidase remained unchanged. The data obtained suggest that ADH effect on the HH activity is mediated by adenylate cyclase mechanism.