[Allelic variants of apolipoproteins B and CII genes in patients with ischemic heart disease and in healthy persons from the Moscow population]. / Allel'nye varianty genov apolipoproteinov B i SP u bol'nykh ishemicheskoi bolezn'iu serdtsa i u zdorovykh lits iz Moskovskoi populiatsii.

Allelic frequencies of a microsatellite of the apolipoprotein CII gene (APOCII) and a minisatellite of the apolipoprotein B gene (APOB) were studied using polymerase chain reaction (PCR). The study was conducted on a random sample of male Moscow inhabitants and a sample of patients with coronary heart disease (CHD) from the same population. Fourteen variants of the APOB minisatellite (the 82% heterozygosity level) and 13 alleles of the APOCII microsatellite (the 85% heterozygosity level) were found. CHD patients significantly differed from the control group in the distributions of alleles in these loci: APOB 32, APOB 46, APOB 48, and APOB 50 as well as APOCII 17 and APOCII 29 were found more frequently. A relationship was found between the distributions of APOB and APOCII in the CHD patients. The CHD patients with alleles APOCII 21 and APOCII 30 very often had the allele APOB 32; and patients with the genotype APOB 34, 36 had the allele APOCII 29 even more often than affected individuals in general. Individuals of the control group with the allele APOCII 30 exhibited hypertriglyceridemia without increased levels of total cholesterol and apolipoprotein B in plasma.

[The rehabilitation of patients with postneuritic contracture of the mimetic muscles by using locally applied cold action]. / Reabilitatsiia bol'nykh postnevriticheskoi kontrakturoi mimicheskikh myshts s primeneniem lokal'nogo dozirovaniia kholodovogo vozdeistviia.

A method is proposed for combined modality treatment of patients with postneuritic contracture of the muscles of expression of various genesis utilizing local hypothermia as well as hypo- and hyperthermic methods of treatment. Clinical effectiveness of the proposed method of treatment of patients in the acute phase of the facial nerve neuritis, non-existence of important contraindications which are usual with the medicamentous and electrophysiotherapeutic methods of treatment of this condition, and absence of supposed complications enable it to be recommended for clinical application.

[The use of hypothermia in the combined treatment of patients with facial neuritis in the acute period]. / Primenenie gipotermii v kompleksnom lechenii bol'nykh nevritom litsevogo nerva v ostrom periode.

Local-dosed hypothermia is a pathogenetically substantiated method of treatment of facial neuritis as it produces a marked anti-inflammatory effect due to development of a persistent reflex vasospasm. The method is effective in the acute stage of the disease, has no contraindications and reduces significantly the chemotherapy load.