1.
Vox Sang
; 103(1): 75-8, 2012 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22098461
RESUMO
Since cytokine--mobilization for granulocyte collections in random donors--is not licensed in Austria, we investigated in a prospective analysis the effects of prednisolone or dexamethasone (DXM) in 153 donors (35 women/118 men) and in the collected products. Either prednisolone (50 mg) intravenously 4 h before granulocyte collection or DXM (8 mg) orally 12 h before collection was given. Collections were performed with the Cobe Spectra (CardianBCT, Lakewood). We recorded a significantly higher percentage of granulocytes in the peripheral blood of the DXM. However, the collected number of granulocytes was equal in both groups.
Assuntos
Remoção de Componentes Sanguíneos/métodos , Dexametasona/administração & dosagem , Granulócitos/citologia , Prednisolona/administração & dosagem , Administração Oral , Adulto , Áustria , Doadores de Sangue , Feminino , Granulócitos/efeitos dos fármacos , Granulócitos/metabolismo , Humanos , Injeções Intraventriculares , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Adulto Jovem
2.
J Thromb Haemost
; 10(1): 156-8, 2012 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22044668