Acute angle-closure glaucoma after total knee replacement surgery: case report and literature review.

An early and correct diagnosis improves the prognosis of post-operative Acute angle closure glaucoma (AACG). A 65 years-old monophtalmus man was operated for a total knee replacement surgery, under general anaesthesia without any adverse events. The day after, the patient described recurrent periorbital pain in his eye, with ocular hyperaemia, and reduced visual acuity. A diagnosis of AACG was made and conservative treatment was started to reduce the intraocular pressure. In the post-operative AACG, several predisposing local factors including genetic predisposition, female gender, hypermetropia, increased lens thickness and small corneal diameter, can be added to a pupillary block induced by adrenergic and anticholinergic drugs used in anaesthetic procedures as risk factors. An acute and intensive periorbital or ocular pain, with or without visual disturbance, must aware the physician.

The Ability of Carbon Dioxide-Derived Indices to Predict Adverse Outcome After Cardiac Surgery.

OBJECTIVE: The objective of this study was to assess whether the central venous-to-arterial carbon dioxide partial-pressure difference (ΔPCO2) and the ratio of the ΔPCO2 to the arterial-venous difference in oxygen content (ΔPCO2/Ca-vO2) predict postoperative complications (PC) after cardiac surgery. DESIGN: Prospective, observational, noninterventional study. PARTICIPANTS: The study comprised 60 patients undergoing cardiac surgery with cardiopulmonary bypass. INTERVENTIONS: The primary endpoint was the occurrence of PC. Data were first analyzed in two groups based on the occurrence of PC. Then, receiver operating characteristic curves of the ΔPCO2 and the ΔPCO2/Ca-vO2 ratio were analyzed for the prediction of PC. MEASUREMENTS AND MAIN RESULTS: Among the study participants, 22 (36.7%) experienced PC. The death rate was 18.3%. The present study found that the ΔPCO2 and the ΔPCO2/Ca-vO2 ratio predicted the occurrence of PC with areas under the curve of 0.702 and 0.666, respectively. The best thresholds of these markers were 8.3 mmHg for the ΔPCO2 and 2.16 mmHg/mL for the ΔPCO2/Ca-vO2 ratio. A significant difference was found for these indicators between the groups with and without PC. The ΔPCO2 and the ΔPCO2/Ca-vO2 ratio were significantly correlated to EuroSCORE II, duration of aortic clamping, majority of prognostic scores the first two days postoperatively, and the lactate level. The ΔPCO2/Ca-vO2 ratio is predictive of hyperlactatemia >2 mmol/L, with an area under the curve of 0.787. CONCLUSION: The ΔPCO2 and the ΔPCO2/Ca-vO2 ratio predict the occurrence of complications in cardiac surgery.