RESUMO
A double-blind study was conducted in 52 patients who received a total of 180 electroconvulsive therapy treatments. Patients were allocated randomly to receive doses of 15 mg, 25 mg or 50 mg of suxamethonium. Those who received suxamethonium 50 mg took significantly longer to breathe again compared with patients who received the lower doses, and were significantly more likely to have a very well modified convulsion than patients who received suxamethonium 15 mg. There were no differences among the groups in the incidences of muscle pains after treatment. We conclude that all three doses were acceptable; however, a dose of 25 mg had practical advantages over 50 mg and theoretical advantages over 15 mg.
Assuntos
Eletroconvulsoterapia , Succinilcolina/administração & dosagem , Adulto , Idoso , Relação Dose-Resposta a Droga , Eletroconvulsoterapia/efeitos adversos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Doenças Musculares/etiologia , Dor/etiologia , Distribuição Aleatória , Respiração/efeitos dos fármacos , Succinilcolina/farmacologia , Tiopental , Fatores de TempoRESUMO
A total of 156 consultant anaesthetists in the North East Thames Regional Health Authority were circulated with a questionnaire on their personal use of ether and cyclopropane and their attitudes towards restriction or withdrawal of these agents: 144 completed questionnaires were received (92% response). Four anaesthetists (3%) claimed to use ether regularly at least once a month and 27 anaesthetists (19%) felt that their anaesthetic practice would suffer if ether were withdrawn. Cyclopropane had 62 regular users (43%) and 65 anaesthetists (45%) felt that their practice would suffer if it were withdrawn. Ninety-two anaesthetists (64%) were prepared to confine their use of explosive agents to either the anaesthetic room or the operating room; of these, three-quarters favoured the anaesthetic room. There were few notable differences in the pattern of use of explosive agents between anaesthetists with more than 21 years in the specialty and those with less than 21 years.
Assuntos
Anestesia por Inalação , Anestesiologia , Atitude do Pessoal de Saúde , Ciclopropanos , Éter , Etil-Éteres , Inglaterra , Explosões , HumanosRESUMO
Preliminary clinical evaluation of a new ventilator, which embodies a new valveless design principle and a circuit which is open to atmosphere, has been performed on adult patients undergoing surgery. Using normal respiratory fresh gas flows (100 ml kg-1 min-1) PaCO2 and PaO2 were the same as with a conventional ventilator. High frequency ventilation (HFV) up to 100 b.p.m. caused no statistically significant changes in PaCO2 and PaO2. The peak airway pressures were 30% less than with a Manley ventilator and decreased by a further 40% during HFV, PEEP, NEEP, CPAP and IMV were easily applied.
