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J Vet Med Sci ; 82(1): 27-30, 2020 Jan 10.
Artigo em Inglês | MEDLINE | ID: mdl-31708538

RESUMO

The immune related factors of peripheral blood mononuclear cells (PBMC) were analyzed in the clinical cases with Mycoplasma (M.) bovis infection. Seventy-eight Holstein calves in one farm were used. These calves were divided into three groups; the calves with M. bovis infection of poor outcome after treatment (Non-Recovery Group), the calves with M. bovis infection recovered (Recovery Group) and clinically healthy calves (Control Group). Blood samples were collected at days of the first medical treatment and the final treatment or euthanasia. IL-17A levels in the Non-Recovery Group were higher than those in the Recovery Group on both days. Our result suggested that the IL-17A of PBMC is an important factor to affect outcome of the calves with M. bovis infection.


Assuntos
Doenças dos Bovinos/tratamento farmacológico , Citocinas/sangue , Leucócitos Mononucleares/imunologia , Infecções por Mycoplasma/veterinária , Animais , Antibacterianos/uso terapêutico , Bovinos , Doenças dos Bovinos/imunologia , Infecções por Mycoplasma/tratamento farmacológico , Infecções por Mycoplasma/imunologia , Mycoplasma bovis/imunologia , Resultado do Tratamento
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