[Giant cell tumor--osteoclastoma: part II]. / Obrovskobunkový nádor--osteoclastoma: II. cast'.

Authors present current views on the comprehensive diagnostics, treatment and prognosis of giant cell tumours. They include an exact algorithm of diagnostics necessary for a timely treatment. They describe an often unexpected behaviour of these tumours which is frequently active and aggressive, to a small extent these tumours show the tendency to become malignant. The treatment prefers curretage, antibiotic irrigation and filling in with bone cement. In case of recurrence and an extensive process, block resection and replacement by an individual implant, in hardly accessible locations (spine, sacrum, pelvis) or radiotherapy is recommended. The authors present in detail results of a 10-year systematic follow-up of 56 patients, of which 61.6% were in active stage, 36.8% in aggressive stage. The most frequently used method (in 73.2%) was curretage, irrigation and filling in with bone grafts, in 12.5% of cases block resection and replacement by bone grafts. Total results after all these types of operations evaluated in the interval of 3 years after the operation were very good, i.e. 85.7% remissions, there were 14.3% of recurrence. Of these setbacks 5.4% were in remission for more than 3 years and thus conduced to the increase of the number of remissions to 94.6% which can be evaluated as an excellent result. Local recurrence occurs in 10-15% with the application and 15-25% without the application of local adjuvant therapy. In the third stage in case of extensive destruction we perform resection en bloc, radiotherapy in hardly accessible locations (spine, sacrum, pelvis). In case of extensive destruction in the region of joints the method of choice is the application of both individual and total replacement.

[Primary intraosseous liposarcoma - case report.]. / Primárny kostný liposarkóm - kazuistika.

Primary intraosseous liposarcoma belongs to exceptional tumors rarely found on the sceleton. There are only several tens of cases described in literature and they are published as case reports. Because there is not enough experience, especially with diagnostics of this illness, it happens that it is considered as malignant fibrous histiocytoma, malignant mesenchymoma or with secondary infiltration of liposarcoma of soft tissue into the bone. Authors tried (in correlation with the clinical outcome studies of macroscopic samples with detailed histologic examination) to overcome diagnostic uncertainities of this case. Key words: primary intraosseous liposarcoma, maligant bone tumors.

[Our Strategy of the Treatment of Giant-cell Tumours Part I - Strategy.]. / Nasa metodika liecby obrovskobunkových kostných nádorov I. cast: metodika.

The authors present a treatment procedure in giant-cell tumours of limbs applied in the recent three years at Ist Orthopaedic Clinic in Bratislava. The procedure begins with cytologic verification (in most cases within one stage procedure by peroperative cytologic examination) followed by careful curretage of the lesion, irrigation by liquid non-diluted solution of phenol, irrigation with pure 96% ethylalcohol, irrigation with physiological solution, filling with bone cement. In the methodological part of the contribution the authors discuss toxicity of phenol and risks of this treatment which they confront with the existing data in the literature. Key words: giant-cell tumours, chemoproteolysis, phenol, bone cement.