RESUMO
We have developed a technique for inserting double-closed-loop posterior chamber implants that minimizes zonular stress with both ciliary sulcus and capsular bag insertion and facilitates in-the-bag placement if desired.
Assuntos
Cristalino/cirurgia , Lentes Intraoculares , Câmara Anterior/cirurgia , Humanos , MétodosRESUMO
Thirty-two ocular hypertensive subjects were treated for 90 days with either 0.5% timolol maleate or 2% epinephrine hydrochloride twice daily to one eye and both drugs to the fellow eye. The ocular hypotensive effects of timolol and epinephrine were partially additive throughout the course of this study. On the 91st day, eyes treated with epinephrine had a 25.8% mean reduction of intraocular pressure from baseline, whereas their fellow eyes treated with epinephrine and timolol had a 33.9% reduction. Eyes treated with timolol had a 27.2% mean reduction of IOP, whereas fellow eyes treated with timolol and epinephrine had a 29% reduction. These results suggest that the majority of patients being treated with either drug are unlikely to have a substantial long-term reduction in IOP when the other drug is added to their therapeutic regimen.
Assuntos
Epinefrina/uso terapêutico , Glaucoma/tratamento farmacológico , Propanolaminas/uso terapêutico , Timolol/uso terapêutico , Administração Tópica , Ensaios Clínicos como Assunto , Interações Medicamentosas , Quimioterapia Combinada , Epinefrina/administração & dosagem , Epinefrina/farmacologia , Humanos , Pressão Intraocular/efeitos dos fármacos , Soluções Oftálmicas , Timolol/administração & dosagem , Timolol/farmacologiaRESUMO
Fifteen years ago a 47-year-old man underwent an evisceration for an unsuspected choroidal melanoma. A bulky recurrence required exenteration. The patient is currently alive and has no evidence of metastatic disease.