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Turk J Med Sci ; 51(3): 912-920, 2021 06 28.
Artigo em Inglês | MEDLINE | ID: mdl-33237663

RESUMO

Background/aim: The aim of this descriptive article is to share the experience in Ege University, Turkey with favipiravir in the treatment of severe SARS-CoV-2 pneumonia. Materials and methods: This retrospective descriptive study included patients diagnosed with COVID-19 who presented with or developed severe pneumonia. Results: Forty patients who completed a full course (at least 5 days) of favipiravir were included in the study. At baseline, 30 (75%) patients required treatment for respiratory distress. Thirty-three patients (82.5%) were discharged from the hospital with full recovery, 6 patients (15%) died and 1 case (2.5%) was still at the intensive care unit (ICU) when this paper was written. Conclusion: This study provides relevant information for the treatment of COVID-19, suggesting that favipiravir was associated with significant clinical and laboratory improvements in the majority of the patients, is a safe drug with no serious side effects and would merit further investigation.


Assuntos
Amidas/uso terapêutico , Tratamento Farmacológico da COVID-19 , Unidades de Terapia Intensiva/estatística & dados numéricos , Pandemias , Pirazinas/uso terapêutico , SARS-CoV-2 , Adulto , Idoso , Antivirais/uso terapêutico , COVID-19/epidemiologia , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Fatores de Tempo , Resultado do Tratamento , Turquia/epidemiologia
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