[Study of acid-base balance parameters and certain electrolytes in acute diarrhea in children after oral hydration with WHO solution]. / Badania parametrów równowagi kwasowo-zasadowej i niektórych elektrolitów w ostrych biegunkach u dzieci po nawadnianiu doustnym plynem wg WHO.

The efficacy was evaluated of oral hydration with WHO solution in children with acute diarrhoea. The beneficial changes were shown of selected acid-base balance parameters and electrolytes in blood serum during this treatment.

[Effect of treatment with HDM vaccine on selected immune parameters in children with bronchial asthma]. / Wplyw leczenia szczepionka HDM na wybrane parametry odpornosci u dzieci z astma oskrzelowa.

The purpose of the study was to trace the changes of certain parameters of humoral and cell-mediated immunity in children with asthma who received the HDM Bencard vaccine as specific immunotherapy. Among the immune parameters the levels of IgG, IgA and IgM and the phagocytosis index were determined, the E-rosette test and the HBT reduction test were done before the beginning of the treatment, after 3 months, 9 months and 3 years of desensitization. The results were subjected to statistical analysis, presented in tables and in diagrams. Of the three determined immunoglobulins only the IgG increased significantly, while the titres of IgA and IgM remained unchanged. Before desensitization the values of the per cent of T-cells in the E-rosette test were below the accepted normal level. During HDM desensitization the per cent of T-cells rose. The phagocytosis index and the NBT reduction test were lower in the asthmatic children than in healthy ones but during the treatment with HDM they reached significantly high values. These results confirmed that mechanism of the action of this immunotherapy is a complex one and influences several structures of the immune system. Raised values of the studied parameters during desensitization correlated with an evident improvement of the clinical status and marked reduction of the frequency of asthma attacks. During the treatment with the HFM vaccine no side effects of this therapy were noted.

[Choledochal cyst in a child]. / Torbiel przewodu zólciowego wspólnego u malego dziecka.

A rare case of common bile duct cyst was observed in a girl aged 22 months. The clinical course of the disease and laboratory investigations necessary for diagnosis are describe in detail. Successful operation confirmed the diagnosis.

[Excretion of catecholamines in juvenile diabetes mellitus]. / Wydalanie amin katecholowych w cukrzycy mlodzienczej.

Twenty four hours' urinary excretion of catecholamines was examined in 30 children suffering from diabetes and in 30 healthy children. The results showed that in children suffering from diabetes, excretion of adrenaline was increased and that of noradrenaline decreased when compared with healthy children. Taking into consideration changes in the sympatho-adrenergic system activity in cases with different degrees of compensation of metabolic processes during insulinization, it should be stressed that in children with ketoacidosis, excretion of catecholamines was still different in comparison with control group. On the other hand in children with compensate diabetes after insulin therapy, that differences were little. Marked increase in free adrenaline excretion observed in children with ketoacidosis and its normalization by effective insulinization seems to support the diabetogenic and ketogenic role of this neurohormone. Decrease in free noradrenaline excretion in children suffering from juvenile diabetes appears to suggest that there is a diminished sensitivity of the sympathetic system resulting probably from specific autonomic neuropathy accompanying this disease.