[Relationship of the quality of drinking water to its use regimens and the types of water supply pipes].

Drinking water running along the pipes made from different materials was investigated. Two experiments could determine the material that assured at least of all the quality of drinking water in accordance with SanPin 2.1.4.1074-01. The mechanism for worsening the quality of water supplied to a user was revealed in relation to the water use regimen. Short-term flow stoppage of water was found to result in its lower oxygen levels, a larger number of different groups of iron- and manganese-reducing bacteria and an enhanced bacterial reduction of oxides. The latter was accompanied by the dissolution of heavy metals, which induced secondary water contamination.

[Problems and perspectives in the hygienic regulation of biotechnological strains of microorganisms].

The state-of-the-art of hygienic standardization of biotechnological strains of microorganisms is considered. The last century's investigations accumulated abundant experimental data on the estimation of the adverse effect of the strains, formulated main guidelines for evaluating the negative activity of producing strains, and proposed a schematic diagram for toxicological and hygienic investigations of new biotechnological strains. Further studies made it possible to elaborate their human hazard classification, to improve study programs, to substantiate a priority list, and to develop approaches to assessing the occupational microbiological risk.

[Biotechnology manufacture as a possible source of environmental pollution and a risk factor for human health]. / Biotekhnologicheskoe proizvodstvo kak vozmozhnyi istochnik zagriazneniia okruzhaiushchei sredy i faktor riska dlia zdorov'ia cheloveka.

The biotechnology-oriented quantitative criteria and a plan of primary sanitary hygienic evaluation of pathogenicity of microorganisms-producers were first established. New evidence of the negative effects of strains-producers on microbiocenosis and self-purification of soils and reservoirs were obtained. The requirement of an all-round hygienic assessment of microorganisms-producers consisting of two mandatory steps, i.e. the primary sanitary hygienic evaluation of pathogenicity of strains and the investigation of effects of these microorganisms on microbiocenosis and soil and reservoir self-purification has been substantiated.