RESUMO
INTRODUCTION: Spontaneous bacterial peritonitis can be differentiated from secondary bacterial peritonitis by the absence of a surgically treatable intra-abdominal source of infection. However, oftentimes this is unapparent and other clinical clues need to be sought after to make the right diagnosis. CASE: A 64-year-old woman was admitted because of three days of worsening diffuse abdominal pain and distention. She was morbidly obese and had a history of non-alcoholic steatohepatitis (NASH) cirrhosis. She was febrile at 38.2 °C. Her abdomen was soft, diffusely tender and distended with a reducible umbilical hernia. Laboratory exam showed a white blood cell count 6700/mcl. Ascitic fluid analysis showed a yellow cloudy fluid with an absolute neutrophil count (ANC) of 720 cells/m3, a total protein of 1.1 g/dl and a lactate dehydrogenase of 242 IU\l. She was given ceftriaxone and albumin. The ascitic fluid culture grew pansensitive Viridans streptococcus. The following days she continued to have fever and abdominal pain and a repeat paracentesis was done which showed improvement in her ANC. Abdominal computed tomography scan was done which showed hernia inflammation with a rim-enhancing fluid collection. Surgery was consulted who did a primary repair of the umbilical hernia and over the next few days the patient improved and was discharged stable. CONCLUSION: Persistence of signs and symptoms of peritonitis despite improvement in ascitic fluid analysis in cirrhotic patients treated for or early relapse of peritonitis with the same organism should prompt the physician to evaluate for secondary peritonitis and surgical management should be considered for potentially correctable sources.
RESUMO
Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) is a rare cause of necrotising fasciitis (NF), and is usually not fulminant as in group A Streptococcus (GAS), the archetypal aetiology. We report an unusually fulminant case of NF by CA-MRSA in an immunocompetent patient. A 52-year-old man presented to the emergency department with 1â week of progressive left thigh pain and swelling. The patient had ecchymoses, bullae and hypoesthesia of the involved skin, and CT scan revealed extensive fascial oedema. He was immediately started on broad spectrum antibiotics. Within 12â h of presentation, he underwent surgical debridement. Despite aggressive supportive care, the patient died less than 24â h after presentation. MRSA, with an antibiogram suggestive of a community-acquired strain, was recovered from intraoperative specimens and admission blood cultures. This case underscores that CA-MRSA, while rarely reported, can cause a fulminant presentation of NF similar to GAS in immunocompetent patients.
Assuntos
Antibacterianos/administração & dosagem , Bacteriemia/microbiologia , Fasciite Necrosante/diagnóstico , Fasciite Necrosante/microbiologia , Staphylococcus aureus Resistente à Meticilina/isolamento & purificação , Infecções Estafilocócicas/diagnóstico , Coxa da Perna/patologia , Bacteriemia/diagnóstico , Infecções Comunitárias Adquiridas/diagnóstico , Infecções Comunitárias Adquiridas/microbiologia , Desbridamento , Evolução Fatal , Humanos , Masculino , Pessoa de Meia-Idade , Infecções Estafilocócicas/microbiologia , Infecções Estafilocócicas/patologia , Coxa da Perna/microbiologiaRESUMO
We studied the use of fungal blood cultures in our hospital. They added little compared to routine culture results, but clinicians ordered them for sicker patients, when facing diagnostic uncertainty, or after prior candidemia. We need a practical guideline for when to order fungal blood cultures.