[Evaluation of the efficacy of a plant adaptogen (spirulina) in the pathognic therapy of primary tuberculosis in children]. / Otsenka efektyvnosti zastosuvannia adaptohenu roslynnoho pokhodzhennia (spiruliny) u patohenetychnii terapii pervinnoho tuberkul'ozu y direi.

The use of spirulina and its efficiency have been studied in a comparative aspect as a systemic biocorrector, in a combined treatment of tuberculosis in 26 children. It has been ascertained that application of spirulina as a pathogenetic means of remediation permits shortening the intoxication syndrome regression time, reducing the frequency of adverse reactions in administering antituberculous preparations.

[Reasons for hospital readmission of infants and preschool children with tuberculosis]. / Prichiny povtornogo postupleniia v statsionar detei, bol'nykh tuberkulezom v rannem i doshkol'nom vozraste.

As high as 12.4% of children suffering from tuberculosis are readmitted, rural children are more frequently readmitted (18.0 versus 7.2%, p < 0.01), children having tuberculosis (10.9%) and nonspecific pathology (1.5%). Among the children readmitted for tuberculosis, 75.9% had exacerbations which provoke infectious diseases in 18.2%. In 72.7% of cases, the cause of readmission was premature discharge due to their parents' noncompliance.

[Improving the activities of tuberculosis sanatoria for children and adolescents]. / Sovershenstvovanie deiatel'nosti tuberkuleznykh sanatoriev dlia detei i podrostkov.

The paper deals with the examination of the state of health of children treated at tuberculosis sanatoria of republican and local importance. At present the tuberculosis sanatoria for children are not considered any more to be strickly uniprofile. The emphasis of their activities is aimed at conducting controlled chemotherapeutic prevention measures among children with small attenuating forms of tuberculosis as well as among those who belong to high risk groups in relation to tuberculosis including concurrent bronchopulmonary diseases of nonspecific etiology.

[Use of computerized tomography in the differential diagnosis of spherical and cavitary formations in the lungs of children and adolescents]. / Primenenie komp'iuternoi tomografii v differentsial'noi diagnostike okruglykh i polostnykh obrazovanii v legkikh u detei i podrostkov.

Computed tomography (CT) of the chest organs was used in a comprehensive examination of 19 children and adolescents with spherical and cavitary formations in their lungs and mediastinum. Comparative analysis of the results obtained by means of routine X-ray examination and CT of the chest organs of the children and adolescents with spherical and cavitary formations in their lungs revealed that CT greatly improved their differential diagnosis. CT provides valuable additional data and is an optimum X-ray method for differential diagnosis of spherical and cavitary formations in children and adolescents.

[The systemic immunity of schoolchildren from foci of tuberculosis infection]. / Sostoianie sistemnogo immuniteta u detei shkol'nogo vozrasta iz ochagov tuberkuleznoi infektsii.

Seventy-eight tuberculin-positive schoolchildren at the age of 7 to 15 years from tuberculosis foci living in special institutions of the sanatorium type were subjected to immunological examination. The control group included 22 noninfected children of the same age. Persons with lower counts of T-lymphocytes and their decreased functional activity, unbalance in their subpopulation composition and positive immunospecific responses to tuberculin predominated among the schoolchildren subjected to the examination. The state of the B-lymphocyte system changed insignificantly. It was concluded that persons with markedly suppressed cellular immunity be treated with immunomodulating agents during the chemoprophylaxis course.

[Comparative estimation of tuberculin reactions using a ruler and thermographic film followed by histological examination of the papule in guinea pigs]. / Sravnitel'naia otsenka tuberkulinovykh reaktsii lineikoi i termograficheskoi plenkoi u morskikh svinok s gistologicheskim izucheniem papuly.

The time course of tuberculin reactions during isoniazid treatment was studied on 10 guinea pigs with experimental tuberculosis. Linear, temperature and histological characteristics of papules were investigated. Thermographic estimation of papules was performed with cholesteric liquid crystal films. For pathohistological examination a new histochemical method developed at the Kiev Research Institute of Phthisiology and pulmonology on the basis of trimethine dyes of the oxanol class of organic solvents (with PK-144) was used along with the routine procedures. A decrease in the temperature gradient (difference of temperatures over papules and the symmetric areas of the skin on the other side of the animal body) was stated irrespective of the papule linear size. The thermographic method for estimating tuberculin reactions based on pathophysiological processes in papules during isoniazid treatment for 2.5 months proved to be a finer procedure for evaluating tuberculin papules than measuring their linear size.