[Preparation of highly-purified melittin from bee venom by an affinity chromatography method]. / Otrimaniia visokoochishchenogo preparatu melitinu z otruti bdzholi metodom afinnoï khromatografiï.

The method of melittin (a lytic peptide from bee venom) purification is described. The method is based on application of immunosorbent with antibodies against phospholipase A2 and permits obtaining peptide without the residual phospholipase activity. It can be also used for the phospholipase A2 purification from melittin admixtures.

[Studies on the heterogeneity of blood serum high-molecular fraction proteins in healthy people and patients with cancer]. / Vivchennia geterogennosti bilikiv visokomolekuliarnoi fraktsii sirovatki krovi zdorovikh liudei ta khvorikh na rak.

Heterogeneity of proteins of blood serum high-molecular fraction in healthy people, patients with cancer and those with pathologies of nonmalignant nature was studied by the method of disc electrophoresis in 4% polyacrylamide gel. It is established that under conditions of the experiment sharp differences are observed in heterogeneity of studied proteins manifesting in a growth of the discrete electrophoretic bands in disc electrophoregrams of high-molecular fractions of sera from the cancer patients. Disc electrophoregrams of proteins of the studied fractions from the sera of patients with nonmalignant pathologies also differ from those of control groups, though not so sharply as when comparing the preparations obtained from the sera of healthy people and cancer patients. Possible reasons of the observed differences are discussed.