[The conclusions from an analysis of 9 approaches to determining the value of KT/Vur]. / Nekotorye vyvody iz analiza 9 podkhodov k opredeleniiu KT/Vur.

Causes underlying different results in estimation of KT/V (ur) according to 9 mathematical models are analyzed. These models are the following: 1) classic approach F.A. Gotch, 2) estimation according to E.G. Lowrei, KT/V = KT/0.6* (body mass), 3) according to R.M. Hakim, KT/V = ln(CoC), 4) according to K.K. Jindal, KT/V = 0.04*(1 - C/Co)*100% - 1.3; 5), 5) according to P. Calzavara, KT/V = (Co - C)*2/(Co + C), 6) according to J.T. Daugirdas, KT/V = ln[C/Co - 0.03 - UF/(dry mass), 7) according to C. Basile, KT/V = 0.023(1- C/Co*100%- 0.284, 8) according to P. Malchesky, 9) according to L. Garred et. al. Basing on the results of examination of a random sample of 120 patients on chronic dialysis it is inferred that the results obtained according to the approaches 1, 3 and 5 are more dependent on emergence of water sectors during the procedure leading to underestimation of KT/V value. In approaches 2, 8 and 9 the dialysis "dose" is estimated with minimal error. It is believed insufficient to estimate dialysis adequacy by KT/V only. It is proposed to make allowances also for the value of the ratio of true to apparent volume of urea distribution. The estimation should be made according to the formula: V/V = ln(Co/C)*0.6* (body mass)/KT.

[Comparison of different ways of measuring the obtained dose of hemodialysis]. / Sravnenie razlichnykh sposobov izmereniia poluchennoi "dozy" gemodializa.

The paper analyses the reasons for different variations from the calculation of KT/V(ur) by using 9 mathematical models. Analysing the survey data on 120 randomly selected patients on chronic hemodialysis has led to the conclusion that the data obtained by models 1, 3, and 5 more greatly depend on the patient's body compartmentization during a dialysis session than those by models 2, 8, 9 and they generally lower KT/V calculations as they overestimate the urea distribution volume, while with models 2, 8, and 9 the resultant dialysis dose is calculated with less errors.

[Erythrocyte deformability in patients with acute myocardial infarction]. / Fil'truemost' éritrotsitov u bol'nykh ostrym infarktom miokarda.

A change in filterability of erythrocytes through a cellulose filter with pores 7 microns in diameter was examined in 67 patients with acute myocardial infarction. Dynamic evaluation of the filterability was compared with a process of necrotic focus development in time. The filterability was ascertained to have various phases coinciding with the development phases of a necrotic focus and to be an early prognostic indicator of myocardial infarction.

[Thermostable leukocyte alpha-glycoprotein: immunochemical study and enzyme activity research]. / Leikotsitarnyi termostabil'nyi al'fa-glikoproteid: immunokhimicheskoe izuchenie i issledovanie fermentnoi aktivnosti.

Using immunochemical analysis with standard antisera, leukocyte thermostable alpha-glycoprotein (LT alpha G) was shown to be distinct from lactoferrin, lysozyme, and fibronectin. The determination of peroxidase and nonspecific elastase in immune precipitates of LT alpha G gave negative results. Affinity sorption of LT alpha G onto the pus protein component was revealed. Purified LT alpha G had amidolytic activity in response to a substrate for elastase (p-nitroanilide succinyl-trialanyl). The ability of LT alpha G to cause the hydrolysis of substrates for thrombin, kallikrein, plasmin was investigated. The identity of LT alpha G and granulocyte elastase is suggested.