[Changes in the electromyographic potentials in cats poisoned with superlethal doses of phosdrin and treated with doline]. / Promeni v elektromiografskite potentsiali u kotki pri otraviane sus supersmurtni dozi fosdrin i lechenie s dolin.

The authors carried out studies on 10 cats, anesthetized by urethane, under atropine protection and under the conditions of artificial respiration and examined the influence of therapeutic antidote of phosphorganic pesticides-Doline on the induced eletromyographic activity during total neuro-muscular block, induced by superlethal doses of phosphadrine. It was established that superlethal doses of phosphadrine induced total block of electropotentials in neuro-muscular conduction of the peripheral musculature, which was removed immediately after venous and muscular administration of the antidote Doline.

[Electrophysiologic shifts in the functional antagonism between phosphororganic pesticides and their antidotes]. / Vurkhu niakoi elektrofiziologichni promeni na funktsionalniia antagonizum mezhdu fosfororganichnite pestitsidi i tekhnite antidoti.

The authors carried out studies on 18 nonanesthetised and anesthetised cats under the conditions of complete imobilization with tricuran and under artificial respiration and examined the temporary consequence of the effects on the spontaneous and induced cerebral activity after poisoning with lethal doses of phosdrine and treatment with Doline, which is the therapeutic antidote of phosphorganic pesticides. The authors established that after lethal poisoning with phosdrin the secondary induced cerebral hypoxia enhanced deepening of the disintegration in the intercerebral interrelationships, which caused the appearence of epileptiform activity. The antidote Doline within 1-2 minutes, after its muscular administration abolished effectively the generalized epileptic seizure and repaired quickly the electrophysiological indices-peculiar for the normal EEG.

[Changes in the bioelectrical activity of the stomach and duodenum in dogs with acute phosphoorganic compound poisoning before and after treatment with preparation H-5/T]. / Promeni v bioelektricheskata aktivnost na stomakha i duodenuma u kucheta pri ostrite intoksikatsii s FOV i lechenie s preparat H-5/T

The results of investigations on bioelectric activity changes in the stomach and proximal duodenum, performed on 12 dogs under acute experiment conditions following poisoning with IMFF, PMFF and MEDETFK poisonous substance and subsequent treatment with the antidote N-5 (T) are reported. Under the effect of the poisonous substances (FOV) investigated, an overall intensification of the motoricity of the stomach and duodenum is established, manifested by the appearance of spice potentials, changes in the rhythm of the slow wave, presence of antiperistalsis and strongly pronounced spasm of the smooth musculature. The listed phenomena are successfully eliminated by the effect of the antidote N-5 (T) within 3-5 min after its injection.