RESUMO
Pathomorphological studies of the degree and expansion of atherosclerotic changes in the cerebrospinal levels in cases of chronic occlusions of the abdominal aorta and the major arteries of the lower extremities revealed marked changes at various levels of section in 12 cases. The morphological changes were characterized by the degenerated architectonics of the spinal cord and by a reduction in its volume in the antero-posterior direction throughout its length. The following considerable histologic alterations were found: the neurones were in various stages of necrobiosis, the selective distribution of the tigroid substance of picnomorphic nature was observed, the axonal reaction was pronounced with central chromatolysis and a shift of the nucleus toward the periphery. There was also a focal fiber destruction in the area of the posterior cornua.