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1.
SAGE Open Med Case Rep ; 7: 2050313X19844379, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31065355

RESUMO

Tuberculosis used to be uncommon in the developed countries but seems to be still on rampant in developing countries. However, there seems to be an increasing occurrence in the developed countries too mainly due to low living conditions, increased migration, HIV immune-compromisation and inappropriate use of antitubercular drugs. Lymphatic tuberculosis is the second commonest extrapulmonary location of tuberculosis followed by genitourinary, bone and joint, miliary, meningeal and abdominal. Abdominal tuberculosis represents nearly 11%-16% of all extrapulmonary tuberculosis locations. Furthermore, abdominal tuberculosis co-exists with pulmonary tuberculosis in 10%-30% of patients. Abdominal tuberculosis remains difficult to diagnose due to non-specific symptoms, variable anatomical locations and lack of specific sensitive diagnostic tools. Diagnosis can be rarely suspected, especially in cases of isolated abdominal tuberculosis without clinical or radiological findings. We present a rare case of a patient with pulmonary tuberculosis combined with intra-abdominal lymphatic tuberculosis causing small intestine volvulus.

2.
Mycopathologia ; 184(1): 159-167, 2019 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-30062390

RESUMO

BACKGROUND: Saksenaea vasiformis is one of the numerous fungi of the Order Mucorales. Rapid progression and invasion of neighboring tissues are the most characteristic features of S. vasiformis mucormycosis. AIM: The objective of this review is the management of this type of infections. METHODS: Case report and literature review. RESULTS: A 62-year old woman, without a history of immunocompromisation, developed a localized cutaneous infection at her right thigh. No trauma, skin laceration or insect bite was reported at the side of infection. The initial treatment was surgical debridements and intravenous administration of amphotericin B/posaconazole. In order to avoid the further rapid progression of the infection and save her life, it was decided to proceed to amputation of the patient's right leg. This is the first case of S. vasiformis cutaneous infection in an immunocompetent patient, in Greece. CONCLUSION: Early diagnosis of S. vasiformis mucormycosis is of paramount importance. Clinical suspicion, based on the rapid progression of the infection and on the medical history of the patient, is sufficient to start antifungal treatment. Broad, aggressive, and repeated surgical debridement of the infection site together with systemic antifungal agents administration is the key point for successful treatment.


Assuntos
Dermatomicoses/diagnóstico , Dermatomicoses/patologia , Mucorales/isolamento & purificação , Mucormicose/diagnóstico , Mucormicose/patologia , Coxa da Perna/patologia , Administração Intravenosa , Anfotericina B/administração & dosagem , Amputação Cirúrgica , Antifúngicos/administração & dosagem , Desbridamento , Dermatomicoses/terapia , Feminino , Grécia , Humanos , Pessoa de Meia-Idade , Mucormicose/terapia , Triazóis/administração & dosagem
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