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1.
Front Psychol ; 7: 1871, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27965609

RESUMO

Objective: The need for validated measures enabling clinicians to classify tinnitus patients according to the severity of tinnitus and screen the progress of therapies in our country led us to translate into Polish and to validate two tinnitus questionnaires, namely the Tinnitus Handicap Inventory (THI) and the Tinnitus Functional Index (TFI). Design: The original English versions of the questionnaires were translated into Polish and translated back to English by three independent translators. These versions were then finalized by the authors into a Polish THI (THI-Pl) and a Polish TFI (TFI-Pl). Participants from three laryngological centers in Poland anonymously answered the THI-Pl (N = 98) and the TFI-Pl (N = 108) in addition to the Polish versions of the Center for Epidemiologic Studies Depression Scale as a measure of self-perceived level of depression, and the Satisfaction With Life Scale to assess self-perceived quality of life. Both were used to determine discriminant validity. Two Visual Analog Scales were used to measure tinnitus annoyance and tinnitus loudness in order to determine convergent validity. Results: Similar to the original version of the THI, the THI-Pl showed a high internal consistency (Cronbach's α = 0.93). The exploratory factor analysis revealed that the questionnaire has a three-factorial structure that does not correspond to the original division for functional, catastrophic, and emotional subscales. Convergent and discriminant validities were confirmed. The TFI-Pl showed high internal consistency (Cronbach's α = 0.96) with the reliability ranging from 0.82 to 0.95 for its different subscales. Factor analysis confirmed an eight-factorial structure with factors assigning all items to appropriate subscales reported in the original version of the questionnaire. Discriminant and convergent validities were also confirmed for the TFI-Pl. Conclusion: We translated and validated the Polish versions of the THI and the TFI to make them suitable for clinical use in Poland.

2.
Int J Occup Med Environ Health ; 25(4): 356-64, 2012 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-23224734

RESUMO

UNLABELLED: Tinnitus is defined as a perception of sound in the absence of an external acoustic stimulus. Several factors are known to influence tinnitus, e.g. hearing loss, noise exposure, age, and hypertension. As only certain individuals develop tinnitus in the presence of the above risks and in approximately 50% of cases tinnitus is not attributed to any particular cause, the question arose whether this inter-individual susceptibility to tinnitus could be explained by the influence of genetic factors. OBJECTIVES: To test the hypothesis that genetic variability in genes of the potassium recycling pathway is associated with increased susceptibility to tinnitus. MATERIALS AND METHODS: The study group consisted of 626 subjects exposed to occupational noise (128 with tinnitus and 498 without tinnitus). 99 single nucleotide polymorphisms were investigated in 10 genes involved in the potassium recycling pathway in the inner ear, previously selected as putative noise-induced hearing loss (NIHL) candidate genes. RESULTS: Nominally significant associations were obtained for 2 variants in KCNE1 (potassium voltage-gated channel, Isk-related family, member 1) and SLC12A2 (solute carrier family 12, member 2) genes. The first gene contributed to tinnitus that developed independently of hearing loss, while the second one was associated with increased susceptibility to noise-induced hearing loss. CONCLUSIONS: Present findings lend support to the notion of potassium recycling pathway genes as possible risk modifiers of tinnitus in individuals with and without hearing loss. Due to the lack of replication in other independent populations these results should be seen as suggestive.


Assuntos
Orelha Interna/metabolismo , Canais de Potássio de Abertura Dependente da Tensão da Membrana/genética , Potássio/metabolismo , Membro 2 da Família 12 de Carreador de Soluto/genética , Zumbido/genética , Estudos de Casos e Controles , Predisposição Genética para Doença/genética , Perda Auditiva Provocada por Ruído/genética , Humanos , Masculino , Polimorfismo de Nucleotídeo Único
3.
Int J Occup Med Environ Health ; 21(4): 301-8, 2008.
Artigo em Inglês | MEDLINE | ID: mdl-19228577

RESUMO

OBJECTIVE: To assess the usefulness of acoustic analysis with vocal loading test for evaluating the treatment outcomes in occupational voice disorders. METHODS: Fifty-one female teachers with dysphonia were examined (Voice Handicap Index--VHI, laryngovideostroboscopy and acoustic analysis with vocal loading) before and after treatment. The outcomes of teachers receiving vocal training (group I) were referred to outcomes of group II receiving only voice hygiene instructions. RESULTS: The results of subjective assessment (VHI score) and objective evaluation (acoustic analysis) improved more significantly in group I than in group II. The post-treatment examination revealed a decreased percentage of subjects with deteriorated jitter parameters after vocal loading, particularly in group I. CONCLUSIONS: Acoustic analysis with vocal loading test can be a helpful tool in the diagnosis and evaluation of treatment efficacy in occupational dysphonia.


Assuntos
Disfonia/diagnóstico , Disfonia/terapia , Docentes , Doenças Profissionais/diagnóstico , Doenças Profissionais/terapia , Adulto , Feminino , Humanos , Pessoa de Meia-Idade , Acústica da Fala , Treinamento da Voz
4.
Int J Occup Med Environ Health ; 20(1): 25-30, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-17708015

RESUMO

INTRODUCTION: Teachers are at risk of developing voice disorders. A clinical battery of vocal function tests should include non-invasive and accurate measurements. The quantitative methods (e.g., voice acoustic analysis) make it possible to objectively evaluate voice efficiency and outcomes of dysphonia treatment. MATERIALS AND METHODS: To identify possible signs of vocal fatigue, acoustic waveform perturbations during sustained phonation were measured before and after the vocal-loading test in 51 professionally active female teachers with functional voice disorders, using IRIS software. All the participants were also subjected to laryngological/phoniatric examination involving videostroboscopy combined with self-estimation by voice handicap index (VHI)-based scale. RESULTS: The phoniatric examination revealed glottal insufficiency with bowed vocal folds in 35.2%, soft vocal nodules in 31.4%, and hyperfunctional dysphonia with a tendency towards vestibular phonation in 19.6% of the patients. In the VHI scale, 66% of the female teachers estimated their own voice problems as moderate disability. An acoustic analysis performed after the vocal-loading test showed an increased rate of abnormal frequency perturbation parameters (pitch perturbation quotient (Jitter), relative average perturbation (RAP), and pitch period perturbation quotient (PPQ)) compared to the pre-test outcomes. The same was true of pitch-intensity contour of vowel /a:/, an indication of voice instability during sustained phonation. DISCUSSION AND CONCLUSIONS: The recorded impairments of voice acoustic parameters related to vocal loading provide further evidence of dysphonia. The voice acoustic analysis performed before and after the vocal-loading test can significantly contribute to objective voice examinations useful in diagnosis of dysphonia among teachers.


Assuntos
Doenças Profissionais/fisiopatologia , Acústica da Fala , Distúrbios da Voz/fisiopatologia , Adulto , Análise de Variância , Distribuição de Qui-Quadrado , Docentes , Feminino , Humanos , Pessoa de Meia-Idade , Doenças Profissionais/diagnóstico , Fonação , Estroboscopia , Distúrbios da Voz/diagnóstico , Qualidade da Voz
5.
Logoped Phoniatr Vocol ; 31(3): 100-6, 2006.
Artigo em Inglês | MEDLINE | ID: mdl-16966152

RESUMO

It has been shown that teachers are at risk of developing occupational dysphonia, which accounts for over 25% of all occupational diseases diagnosed in Poland. The most frequently used method of diagnosing voice diseases is videostroboscopy. However, to facilitate objective evaluation of voice efficiency as well as medical certification of occupational voice disorders, it is crucial to implement quantitative methods of voice assessment, particularly voice acoustic analysis. The aim of the study was to assess the results of acoustic analysis in 66 female teachers (aged 40-64 years), including 35 subjects with occupational voice pathologies (e.g., vocal nodules) and 31 subjects with functional dysphonia. The acoustic analysis was performed using the IRIS software, before and after a 30-minute vocal loading test. All participants were subjected also to laryngological and videostroboscopic examinations. After the vocal effort, the acoustic parameters displayed statistically significant abnormalities, mostly lowered fundamental frequency (Fo) and incorrect values of shimmer and noise to harmonic ratio. To conclude, quantitative voice acoustic analysis using the IRIS software seems to be an effective complement to voice examinations, which is particularly helpful in diagnosing occupational dysphonia.


Assuntos
Docentes , Doenças Profissionais/diagnóstico , Acústica da Fala , Prega Vocal/patologia , Distúrbios da Voz/diagnóstico , Adulto , Estudos de Casos e Controles , Feminino , Humanos , Laringoscopia , Pessoa de Meia-Idade , Doenças Profissionais/fisiopatologia , Polônia , Análise de Regressão , Estroboscopia , Gravação de Videoteipe , Distúrbios da Voz/fisiopatologia , Qualidade da Voz
6.
Int J Occup Med Environ Health ; 19(4): 235-45, 2006.
Artigo em Inglês | MEDLINE | ID: mdl-17402219

RESUMO

OBJECTIVES: Individual susceptibility to noise-induced hearing loss (NIHL) depends on the interaction between intrinsic and environmental factors. To proceed with the study on NIHL susceptibility genes an appropriate selection of workers susceptible and resistant to noise is crucial. The aim of the study was to compare four different methods of subject classification by the susceptibility to NIHL in a group of 949 workers of an electric power plant exposed to steady-state noise at the workplace. MATERIALS AND METHODS: One method based the classification of the workers on the international reference standard ISO 1999:1990; from the entire group of workers, 10% of the subjects with the worst hearing thresholds (HT) in the model were categorized as susceptible to NIHL, whereas 10% of the subjects with the best HT were categorized as resistant to noise. According to three other methods, the entire group of workers was first divided into subgroups by age, duration of employment and the level of noise, and then 10% of the subjects at each HT extreme were selected. RESULTS: The first classification allowed to achieve an excellent separation between HT of the susceptible and resistant subgroups. The susceptible subgroup was significantly younger than the resistant one, showed a shorter duration of employment and a lower level of noise exposure, which is in line with the definition of increased vulnerability to NIHL. The three other methods produced poorer separation of HT with smaller or no gap between HT values in subgroups. CONCLUSIONS: The selection of subjects from the entire worker population of a given industry based on the ISO 1999:1990 standard can be regarded as the most reliable method of classification of noise-susceptible and noise-resistant workers to be used in the future genetic studies on NIHL susceptibility genes.


Assuntos
Perda Auditiva Provocada por Ruído/classificação , Ruído Ocupacional/efeitos adversos , Exposição Ocupacional/legislação & jurisprudência , Adulto , Fatores Etários , Audiometria de Tons Puros , Emprego , Humanos , Masculino , Pessoa de Meia-Idade , Valores de Referência , Estudos Retrospectivos , Fatores de Risco
7.
Environ Toxicol Pharmacol ; 19(3): 547-53, 2005 May.
Artigo em Inglês | MEDLINE | ID: mdl-21783525

RESUMO

BACKGROUND: : Numerous organic solvents applied in industry, like toluene, styrene, xylene and n-hexane have been demonstrated to impair hearing in animals. However, the effects of exposure to a given organic solvent and the interaction of noise and solvents on hearing in humans are still not fully recognized. STUDY DESIGN: : The study was aimed to assess the effects of occupational exposure to solvents alone or in combination with noise on hearing in 1117 employees of yacht, ship, plastic, shoe, and paint and lacquer industry. These persons were exposed either to the mixture of organic solvents with xylene as the main component, or predominantly to styrene, or to the mixture of n-hexane and toluene. Detailed questionnaire data and pure-tone audiometry were compared with data of the reference group that included white collar workers, exposed neither to solvents nor noise and metal factory workers exposed to noise only. In all statistics, the confounding factors were recognized as gender, age, exposure to noise, and other variables occurring at a different rate in study and reference group. RESULTS: : Odds ratio (OR) of hearing loss related with the particular exposure to chemicals was 2.4 (95%CI 1.59-3.74) in case of solvent mixture, 3.9 (95%CI 2.4-6.2) in case of styrene and 5.3 (95%CI 2.6-10.9) in case of n-hexane and toluene exposure. The odds of developing hearing loss substantially increased in the case of combined exposure to organic solvents and noise as compared to isolated exposure to each of these hazards. The highest OR (over 20-fold) was demonstrated in subgroups of subjects exposed simultaneously to noise and two ototoxic solvents (i.e. styrene and toluene or n-hexane and toluene). The mean hearing thresholds were significantly higher in the solvent-exposed groups than in the reference group. The differences in thresholds were observed at high frequencies in the solvent mixture- and n-hexane + toluene-exposed groups and at all frequencies in the styrene-exposed group. A positive linear relationship existed between exposure to solvents and hearing thresholds at high frequencies. CONCLUSIONS: : The results of the study provide the epidemiological evidence that exposure to organic solvents in humans is associated with an increased risk of hearing loss. The simultaneous exposure to organic solvents and noise seems to enhance the hearing deficit if compared with isolated exposures.

8.
Int J Occup Med Environ Health ; 17(2): 285-93, 2004.
Artigo em Inglês | MEDLINE | ID: mdl-15387085

RESUMO

OBJECTIVES: Firearm is a common source of impulse noise that may potentially damage hearing organ. It has been suggested that otoacoustic emissions, particularly transient-evoked otoacoustic emissions (TEOAE), might be more sensitive than pure-tone audiometry (PTA) in the assessment of changes to cochlea caused by noise. The aim of this study was to: (i) evaluate exposure to impulse noise from small-caliber weapons, (ii) compare the post-exposure changes in hearing measured by PTA and TEOAE and correlate them with noise parameters. MATERIALS AND METHODS: The study included 18 male hunters (group I) and 28 candidate policemen (group II) exposed to impulse noise from small firearms during target practices. Group I was unprotected during shooting, whereas group II used commonly available hearing protectors. PTA and TEOAE were performed before and 2-10 min after shooting. Exposure to impulse noise was evaluated by in situ measurements. RESULTS: Groups I and II were exposed to 3-4 and 4-144 impulses of noise at mean C-weighted peak sound pressure levels of 154 dB and 156 dB, respectively. No post-exposure audiometric threshold shift was observed in group I. Significant reductions of TEOAE levels were found both for the whole response (-2.2 dB SPL) and for 1/2 -octave band responses in the frequency range of 1000-4000 Hz (from -1.6 to -3.0 dB SPL). These changes were not correlated with C-weighted peak sound pressure levels or equivalent-continuous A-weighted sound pressure level. Significant correlation was found for peak sound pressure and maximum sound pressure levels in 1/3-octave bands in the frequency range corresponding with the main part of the acoustic energy of impulses (correlation coefficients r from -0.58 to -0.77, p < 0.05). In group II neither PTA nor TEOAE showed significant hearing impairment after shooting. CONCLUSIONS: The results show that even short-term exposure to impulse noise from small-calibre firearms might cause temporary hearing impairment measured by TEOAE. Therefore, the use of earmuffs is strongly recommended, because most of them seem to effectively attenuate impulse noise from small-calibre firearms.


Assuntos
Armas de Fogo , Perda Auditiva Provocada por Ruído/etiologia , Ruído Ocupacional , Adulto , Audiometria/métodos , Limiar Auditivo , Dispositivos de Proteção das Orelhas , Potenciais Evocados Auditivos , Perda Auditiva Provocada por Ruído/epidemiologia , Perda Auditiva Provocada por Ruído/fisiopatologia , Perda Auditiva Provocada por Ruído/prevenção & controle , Humanos , Atividades de Lazer , Masculino , Pessoa de Meia-Idade , Polônia/epidemiologia , Polícia
9.
J Occup Environ Med ; 46(1): 30-8, 2004 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-14724476

RESUMO

Questionnaire and audiometric data of 701 dockyard workers (517 noise and organic solvent mixture-exposed and 184 noise-only-exposed) were referred to 205 control subjects not exposed to either noise or solvents. The odds ratio (OR) of hearing loss was significantly increased by approximately 3 times in the noise-only group and by almost 5 times in the noise and solvent group. A moderate effect of solvent ototoxicity, in addition to noise, was observed on hearing threshold at a frequency 8 kHz. ORs for hearing loss were 1.12 for each increment of 1 year of age, 1.07 for every decibel of lifetime noise exposure (dB-A), and 1.004 for each increment of the index of lifetime exposure to solvents. The results suggest an additive damaging effect of coexposure to noise and organic solvents to the auditory organ.


Assuntos
Perda Auditiva/etiologia , Ruído Ocupacional/efeitos adversos , Exposição Ocupacional/efeitos adversos , Solventes/efeitos adversos , Adulto , Feminino , Perda Auditiva/induzido quimicamente , Perda Auditiva/epidemiologia , Humanos , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Razão de Chances , Risco , Inquéritos e Questionários
10.
J Occup Environ Med ; 45(1): 15-24, 2003 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-12553175

RESUMO

Ototoxicity of styrene and the synergistic action of styrene and noise have been shown in rats. The respective data in humans are scarce and equivocal. This study evaluated the effects of occupational exposure to styrene and combined exposures to styrene and noise on hearing. The study group, comprised of 290-yacht yard and plastic factory workers, was exposed to a mixture of organic solvents, having styrene as its main compound. The reference group, totaling 223 subjects, included (1) white-collar workers, exposed neither to solvents nor noise and (2) metal factory workers, exposed exclusively to noise. All subjects were assessed by means of a detailed questionnaire and underwent otorhinolaryngological and audiometric examinations. Multiple logistic regression analysis revealed almost a 4-fold (or 3.9; 95% CI = 2.4-6.2) increase in the odds of developing hearing loss related to styrene exposure. The factors adjusted for were: age, gender, current occupational exposure to noise, and exposure to noise in the past. In cases of the combined exposures to styrene and noise, the odds ratios were two to three times higher than the respective values for styrene-only and noise-only exposed subjects. The mean hearing thresholds--adjusted for age, gender, and exposure to noise--were significantly higher in the solvent-exposed group than in the unexposed reference group at all frequencies tested. A positive linear relationship existed between an averaged working life exposure to styrene concentration and a hearing threshold at the frequencies of 6 and 8 kHz. This study provides the epidemiological evidence that occupational exposure to styrene is related to an increased risk of hearing loss. Combined exposures to noise and styrene seem to be more ototoxic than exposure to noise alone.


Assuntos
Perda Auditiva Provocada por Ruído/epidemiologia , Doenças Profissionais/epidemiologia , Exposição Ocupacional/efeitos adversos , Estireno/efeitos adversos , Adulto , Audiometria de Tons Puros , Fatores de Confusão Epidemiológicos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Razão de Chances , Polônia/epidemiologia , Análise de Regressão
11.
Med Pr ; 53(3): 229-32, 2002.
Artigo em Polonês | MEDLINE | ID: mdl-12369505

RESUMO

One of the major causes of frequent voice disorders in teachers is incorrect vocal emission technique. The aim of the study was to assess the effect of logopedic training on voice emission parameters and vocal organ disorders in students attending the college for teachers. The study group comprised 45 female students who experienced vocal abnormalities after excessive vocal effort. Questionnaire surveys, phoniatric and videostroboscopic examinations were performed in all subjects before starting and after completing the logopedic training. The training was preceded by a theoretical seminar on voice organ anatomy, physiology, and hygiene. The logopedic training lasting two-three months contributed to the improvement in voice characteristics and the condition of voice organ in the majority of students, as well as in phoniatric parameters, including the increase in the maximum phonation time, the frequency range of voice, the reduction of the glottal insufficiency and the elimination of "soft" vocal nodules. The results of the study indicate that the implemented voice emission training improved significantly voice quality and allowed for providing an efficient therapy of already existing functional disorders of the larynx.


Assuntos
Doenças da Laringe/prevenção & controle , Doenças Profissionais/prevenção & controle , Fonação , Prega Vocal , Distúrbios da Voz/prevenção & controle , Treinamento da Voz , Adulto , Feminino , Humanos , Doenças da Laringe/etiologia , Doenças Profissionais/etiologia , Fonação/fisiologia , Polônia , Estudantes , Inquéritos e Questionários , Ensino , Fatores de Tempo , Resultado do Tratamento , Prega Vocal/fisiologia , Distúrbios da Voz/etiologia
12.
Int J Audiol ; 41(2): 113-9, 2002 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-12212856

RESUMO

With the discovery of otoacoustic emissions (OAEs), the efferent cochlear system has become accessible for investigation in humans. Recently, it has been suggested that contralateral sound activated OAE efferent suppression may provide an early indication of auditory damage due to exposure to noise. In this study, OAE efferent suppression in normally hearing subjects, occupationally exposed to noise, was compared with respective effects in healthy, non-exposed subjects. The noise-exposed group exhibited higher mean hearing thresholds at frequencies 4, 6 and 10 kHz (p < 0.01) and lower-level transient-evoked otoacoustic emission (TEOAE) and distortion-product otoacoustic emission (DPOAE) at a frequency of 4 kHz (not significant). TEOAE efferent suppression was moderately decreased, whereas DPOAE efferent suppression was negligible, in the exposed group compared to non-exposed subjects. The results of the study suggest that OAEs, particularly DPOAE contralateral suppression, are likely to become a valuable method for assessing early hearing damage caused by exposure to noise.


Assuntos
Transtornos da Audição/etiologia , Transtornos da Audição/fisiopatologia , Ruído Ocupacional/efeitos adversos , Doenças Profissionais/etiologia , Doenças Profissionais/fisiopatologia , Emissões Otoacústicas Espontâneas/fisiologia , Testes de Impedância Acústica , Adulto , Audiometria de Tons Puros , Limiar Auditivo/fisiologia , Transtornos da Audição/diagnóstico , Humanos , Masculino , Doenças Profissionais/diagnóstico , Reflexo/fisiologia , Estapédio/fisiologia
13.
Noise Health ; 3(12): 75-84, 2001.
Artigo em Inglês | MEDLINE | ID: mdl-12678942

RESUMO

Otoacoustic emissions (OAEs) are a sensitive and frequency-specific tool for assessing cochlear damage. Parameters of an OAE signal decrease at the frequency that approximately corresponds with the injured region. However, damage in the basal turn of the cochlea is important for signal processing and OAE generation in the higher cochlear partition. In workers exposed to noise, the amplitude of OAEs decreases at the frequencies characteristic for acoustic trauma. These changes may occur prior to the audiometric threshold shift, which supports the superiority of OAEs in early detection of noise-induced damage. Therefore, OAEs may be applied as a quantitative test for individual assessment and monitoring of industrial hearing loss. Otoacoustic emissions are an established screening tool in the examination of newborn and infant hearing. In addition, studies on adult patients demonstrate high sensitivity and specificity if applied in screening sensorineural hearing loss, especially with multivariate analyses engaged. OAEs may be used as a screening test in subjects with an increased risk of exposure to noise and in epidemiological studies on industrial and environmental noise effects. Although otoacoustic emissions have a remarkable advantage in the evaluation of industrial hearing loss, there are some doubts about their utility in hearing conservation programs. The legislation and financial compensation associated with the diagnosis of occupational illness are based on the quantitative "gold standard", pure-tone audiometry. In addition, as it is not possible to reproduce the audiogram precisely, the OAEs may not be currently applied as a reliable test of hearing loss in malingerers. However, in some countries where tinnitus is eligible for compensation, OAEs may indeed appear helpful in the reliable diagnosis of cochlear damage within the respective frequency range.

14.
Noise Health ; 1(2): 50-57, 1999.
Artigo em Inglês | MEDLINE | ID: mdl-12689508

RESUMO

It has been suggested that otoacoustic emissions, particularly transient-evoked otoacoustic emissions (TEOAE), might be more sensitive in assessment of changes to the cochlea caused by noise than pure-tone audiometry (PTA). The aim of the study was to compare temporary threshold shifts with the changes in TEOAE following a six-hour exposure to industrial noise at the intensity of 85-97 dB (A). Thirty two male employees of a metal factory were screened. TEOAE, PTA and tympanometry were included in the hearing test battery. Both, PTA and TEOAE showed significant reduction due to noise exposure, but no correlation between temporary threshold shifts and decreases in either the overall TOAE level or the level of otoacoustic emission in the frequency bands was found. Our results confirm the high sensitivity of TEOAE to short exposure to industrial noise. This study may recommend this measurement as a method of evaluation for TTS conditions for hearing conservation programme purposes, in addition to pure-tone audiometry.

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