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1.
Horm Res Paediatr ; 93(2): 94-107, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32580197

RESUMO

BACKGROUND: Obesity in childhood and adolescence represents a major health problem of our century. In Greece, 30-35% of children and adolescents are overweight or obese. Objective and Hypotheses: To investigate the effectiveness of a comprehensive multidisciplinary personalized management plan at reducing the prevalence of overweight and obesity in childhood and adolescence. PATIENTS AND METHODS: One thousand (n = 1,000) children and adolescents aged 2-18 years (mean age ± SD: 10.09 ± 2.86 years; 520 females, 480 males) were studied prospectively. Subjects were classified as obese (n = 579, 57.9%), overweight (n = 295, 29.5%) or having a normal body mass index (BMI) (n = 126, 12.6%) according to the International Obesity Task Force cutoff points. All subjects were evaluated by a multidisciplinary team at frequent intervals, received personalized advice on diet and exercise and were studied prospectively for 1 year. Detailed clinical evaluation and laboratory investigations were performed at the beginning and at the end of the study. RESULTS: At initial evaluation, 57.9% of subjects were obese, 29.5% overweight and 12.6% of normal BMI. Indices of cardiometabolic disease were higher in obese than in overweight and normal-BMI subjects. Following 1 year of multidisciplinary management interventions, the prevalence of obesity decreased by 16.8%, the prevalence of normal BMI increased by 8.2%, and all cardiometabolic indices improved significantly. CONCLUSIONS: A personalized multidisciplinary management plan is effective at reducing the prevalence of obesity in childhood and adolescence.


Assuntos
Sobrepeso/terapia , Obesidade Infantil/terapia , Adolescente , Índice de Massa Corporal , Criança , Pré-Escolar , Gerenciamento Clínico , Feminino , Grécia/epidemiologia , Humanos , Masculino , Sobrepeso/epidemiologia , Obesidade Infantil/epidemiologia , Prevalência
2.
Eur J Clin Invest ; 49(2): e13042, 2019 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-30368796

RESUMO

BACKGROUND: Childhood obesity represents a major health problem of our century. The benefits of natural products, such as honey, in the management of obesity have gained renewed interest. In this study, we investigated the effect of honey on glucose and insulin concentrations in obese prepubertal girls. MATERIALS AND METHODS: Thirty healthy obese girls aged 10.55 (±SEM:0.34) years with a mean body mass index (BMI) above the 97th centile for age (28.58 ± 1.40 kg/m2 , BMI z-score 2.96) underwent a standard oral glucose tolerance test (OGTT) followed by an oral honey tolerance test (OHTT) 2 weeks later. Both solutions contained 75 g of glucose. Subsequently, subjects were randomized to receive either 15 g of honey or 15 g of marmalade daily, while both groups complied with dietetic instructions. Six months later all subjects were re-evaluated with an OGTT and an OHTT. RESULTS: At the end of the study, all subjects demonstrated a significant reduction in BMI (27.57 ± 1.40, z-score: 2.54 vs 28.58 ± 1.40 kg/m2 , z-score: 2.96, P < 0.001), however, there were no significant differences in BMI and all parameters tested between the group that received honey and the control group. The areas under the concentration-time curve for glucose and insulin for the entire population were significantly lower following ingestion of honey than glucose solution (P < 0.001) both at the beginning and at the end of study. CONCLUSIONS: These findings indicate that honey does not have an effect on stimulated plasma glucose and serum insulin concentrations compared with the standard glucose solution in obese prepubertal girls.


Assuntos
Glicemia/metabolismo , Mel , Insulina/metabolismo , Obesidade Infantil/sangue , Biomarcadores/metabolismo , Índice de Massa Corporal , Criança , Feminino , Seguimentos , Glucose/administração & dosagem , Teste de Tolerância a Glucose , Humanos , Edulcorantes/administração & dosagem
3.
Public Health Nutr ; 11(11): 1142-8, 2008 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-18167168

RESUMO

OBJECTIVE: To examine whether the self-reported fruit and vegetable consumption of Greek primary-school children is associated with the home availability of fruit and vegetables. DESIGN: Cross-sectional study. SETTING: Five primary schools in the city of Pyrgos in south-west Greece. SUBJECTS: One hundred and sixty-seven students in fifth and sixth grades. METHODS: Fruit and vegetable consumption was assessed using an FFQ. Home availability of fruit and vegetables was assessed using a modified version of a US home availability questionnaire. Participant BMI was assessed and parental education obtained by self-report. Hierarchical regression models that took account of the clustering of participants in schools were used to examine the relationship between consumption and availability after controlling for parental education and BMI. RESULTS: Regression analyses showed that home availability of fruit was a significant predictor of consumption (beta=0.524, Z=9.77, P<0.001) in a model that explained 46 % of the overall variance. Home availability of vegetables was a significant predictor of vegetable intake (beta=0.378, Z=6.23, P<0.001) in a model that explained 29 % of the overall variance. CONCLUSION: Home availability of fruit and vegetables was associated with consumption among Greek primary-school children. The association between home availability of fruit and intake was higher than the associations that have been reported in other samples. Results support focusing on the home availability of fruit and vegetables as a potential mediator of consumption that could be manipulated as a means of increasing fruit and vegetable intake among children.


Assuntos
Comportamento Alimentar/psicologia , Abastecimento de Alimentos/estatística & dados numéricos , Frutas/provisão & distribuição , Pais/psicologia , Autorrevelação , Verduras/provisão & distribuição , Adolescente , Índice de Massa Corporal , Criança , Análise por Conglomerados , Estudos Transversais , Inquéritos sobre Dietas , Escolaridade , Feminino , Grécia , Conhecimentos, Atitudes e Prática em Saúde , Humanos , Masculino , Relações Pais-Filho , Pais/educação , Análise de Regressão , Inquéritos e Questionários
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