RESUMO
Choroidal metastasis from prostate cancer is very rare and usually presents late during the disease. Since 2010, many new drugs were approved in the treatment of castrationresistant prostate cancer, including Abiraterone acetate. We report a case of bilateral choroidal metastases from prostate cancer 3 months after the initiation of Abiraterone. Abiraterone was not efficient in controlling the progression of the disease in this case, especially the choroidal metastasis. More case reports are essential in order to evaluate the role of Abiraterone in controlling choroidal metastases from prostate adenocarcinoma.
Assuntos
Androstenos/uso terapêutico , Antineoplásicos/uso terapêutico , Neoplasias de Próstata Resistentes à Castração/tratamento farmacológico , Progressão da Doença , Humanos , Masculino , Metástase Neoplásica , Resultado do TratamentoRESUMO
A case of grade III lipemia retinalis is reported in a 14-year-old girl presenting to the emergency department with fatigue and somnolence. Diabetic ketoacidosis diagnostic of type 1 diabetes mellitus and severe hypertriglyceridemia (23,508 mg/dL) were found on routine blood tests. The patient was admitted to the hospital, kept NPO, and intravenous insulin was started. Her symptoms rapidly improved as did the lipid panel and fundus exam. Cases of lipemia retinalis described in the literature typically occur at a blood triglyceride level above 2,000-2,500 mg/dL. A high level of chylomicrons is responsible for the milky appearance of the serum and retinal vessels. Once the blood triglyceride level decreases significantly, the fundus appearance usually returns to normal.
