[Mania after COVID-19 Infection]. / Manie nach COVID-19-Infektion.

We report the first manifestation of mania in an 85-year-old patient who had not previously received any psychiatric treatment. The patient had had Alzheimer's type dementia for 3 years. The COVID-19 infection took a mild course in accordance with the RKI guidelines. This was followed by a manic syndrome according to the ICD-10 with a clearly elevated mood, increased drive and behavior that occured for the first time in the patient's life.

[Electroconvulsive therapy in a female patient with a cavernous malformation in the medulla oblongata]. / Elektrokonvulsionstherapie bei einer Patientin mit Kavernom in der Medulla oblongata.

The implementation of ECT treatment should not be ruled out in principle even if there is a cavernoma of the medulla oblongata with previous bleeding, but it requires appropriate conditions such as neurosurgical consultation, strict blood pressure monitoring and special information from the patient.

[Hypersexuality Induced by Aripiprazole]. / Sexuelle Enthemmung bei Therapie mit Aripiprazol.

Hypersexual behavior can be assumed as a rare side effect of treatment with aripiprazole and is possibly due to partial agonism on dopamine receptors or partial agonism on 5-HT1A receptors and 5 HT2A antagonism.

[Hypothermia during Treatment with Aripiprazole]. / Hypothermie unter der Gabe von Aripiprazol.

Disturbances of thermoregulation are a well-known side effect of neuroleptic treatment, especially hyperthermia. Hypothermia can occur also during treatment with neuroleptics. Now hypothermia is more and more due to atypical neuroleptics in relation to 5-HT2A antagonism. We report the case of a patient (92 years) suffering from dementia with a hypothermia during treatment with aripiprazole.

[Electroconvulsive Therapy in Presence of Intracranial Titanium Material]. / Elektrokonvulsionstherapie bei einem Patienten mit intrakraniellen titanhaltigen Metallplatten.

We report the case of a 24 year old man, suffering from schizophrenia who has an frontobasal osteosynthesis after an attempted suicide by jumping from a bridge. He received 14 treatments of electroconvulsive therapy (ECT), the electrode position was right unilateral. The treatment was successful and without any complications. Although the patient received a neuroleptic treatment before, he had florid positive symptoms. Hence, we considered ECT as a helpful treatment. The patient and also his legal guardian gave a written informed consent. The ECT was carried out during his stay in a forensic hospital. We therefore consider ECT a secure treatment in this case.

[QTc prolongation during treatment with agomelatine]. / QTc-Zeit-Verlängerung unter Therapie mit Agomelatin.

A 58 years old woman with a depression showed a QTc prolongation during treatment with agomelatine which was fully reversible after stopping administration. QTc prolongation during antidepressant treatment is not unknown especially when tricyclic antidepressants are administered. This case is the first occurrence of a QTc prolongation during treatment with agomelatine.

[Gilles-de-la-Tourette Syndrome as a Tardive Dyskinesia]. / Gilles-de-la-Tourette-Syndrom als tardive Dyskinesie.

Following ten years of continuous olanzapine therapy a 51 years old man developed a Gilles de la Tourette syndrome which disappeared after changing to amisulprid. The Tourette-syndrome will be attributed to a tardive dyskinesia induced by olanzapine.

[The serotonin syndrome]. / Das Serotoninsyndrom.

The serotonin-syndrome is a possible side-effect in the treatment with serotonergic drugs. There are diagnostic criteria for diagnosis of this syndrome. After discontinuation of administering the serotonergic drug is fully reversible.

[Pharmacological treatment of kleptomania--review]. / Pharmakotherapie der Kleptomanie--Literaturübersicht.

According to most diagnostic manuals such as ICD-10 and DSM-IV, kleptomania is classified as an impulse-control disorder. With regard to comorbidity, kleptomania is related to the obsessive- compulsive disorder spectrum and to the broader spectrum of affective disorders. Accordingly a psychopharmacological intervention with anti-depressant drugs or mood stabilizers may be possible, even though there are to date no known results from controlled therapy studies. Nevertheless the successful administration of such medication has been reported in several cases. Assuming a disturbed central serotonin reuptake, the use of selective serotonin reuptake inhibitors (SSRI) seems to be indicated. But also naltrexone could be of use in kleptomania.

[Olanzapine-induced diabetes mellitus]. / Manifestation eines Diabetes mellitus unter Therapie mit Olanzapin.

A potential side-effect in the treatment with olanzapine is hyperglycemia or new onset diabetes mellitus. There are possible mechanisms by which olanzapine could interfere with glucose metabolism but decreased insulin sensitivity due to weight gain is of most relevance.