[Cervicitis and cervical intraepithelial neoplasia: cytomorphological and molecular biology analysis]. / Tservitsit i tsrevikal'naia intraépitelial'naia neoplaziia: tsitomorfologicheskii i molekuliarno-biologicheskii analiz.

The actual research has shown that the important factor of CIN occurrence in the HPV presence is a chronic bacterial cervicitis. Another research of the HPV associations with other urogenital infections has shown that mycoplasma and papillomavirus associations are dominating and they occur twofold often in all of the examined women with cervical pathology in comparison with healthy persons. Inflammatory processes in cervix of the uterus should be related to factors of the increased risk of CIN development.

[Immunologic status of children living in a region with an increased level of nitrates in the drinking water]. / Immunnyi status detei, prozhivaiushchikh v raione s povyshennym soderzhaniem nitratov v pit'evoi vode.

Practically healthy schoolchildren living in the district with a high content of nitrates in drinking water experienced distinct quantitative and functional changes of immune indicators: violation of the ratio of immunoregulatory lymphocyte subpopulations, the high level of spontaneous T-lymphocyte blastogenesis, IgE-hyperglobulinemia. The above changes of the immune system could indicate both body sensitization and its desadaptation under unfavourable conditions.

[Effect of metronidazole on the course of experimental anaerobic streptococcal pneumonia]. / Vliianie metronidazola na techenie éksperimental'noi anaérobnoi streptokokkovoi pnevmonii.

The effect of metronidazole in experimental anaerobic pneumonia in guinea pigs infected with peptostreptococci has been studied. In the untreated animals the prolonged pathological process in the lungs is mainly associated with the suppression of the functional state of the thymus-dependent link of the immune system. Metronidazole suppresses anaerobic flora, stimulates local immune reaction and arrests the development of inflammatory changes in the lungs. The drug eliminates the unbalance in some subpopulations of immunocompetent cells and restores the number of cells regulating immune response to the normal level. The results obtained in this investigation make it possible to recommend the trial of metronidazole in the complex therapy of peptostreptococcal pneumonia.

[Electron microscopic study of the respiratory organs in experimental respiratory mycoplasmosis]. / Elektronno-mikroskopicheskoe issledovanie organov dykhaniia pri éksperimental'nom respiratornom mikoplazmoze.

Comparative pathology of respiratory M. pneumoniae infection in rats, rabbits, and monkeys was studied. The time course of pathological processes in the lungs was investigated by light and immunoluminescent microscopy. Electron microscopy showed M. pneumoniae to be fixed on the surface of the epithelium of the upper respiratory tract; mycoplasmal penetration into a alveolocytes and macrophages, the development of degenerative changes, and death of the affected cells were followed. Multiplication of mycoplasmas in the septal stroma leading to alternative lesions of the endothelium of capillaries and other aerohematic barrier structures was proved. The genesis of these processes is discussed.