[Investigation of the level of genetical safety of urban population].

As it is universally recognized, the population is a sound criteria of the environment quality. The most reliable method to evaluate genetic processes in a population under the condition of the environmental pollution is genetic monitoring, a survey of dynamic parameters of genetic load. An evaluation of genetical safety of an urbanized area of a city is represented in this article. The parameters of genetic load like congenital malformations and multifactorial diseases have been used in the models of monitoring. The analysis and comparison of disease frequencies in Kharkiv Dzerzhinsky District, in other European populations and in regional rural districts with various levels of production have been made.

[Effect of acute hypoxia on coronary and systemic hemodynamics]. / Vliianie ostroi gipoksii na koronarnuiu i sistemnuiu gemodinamiku.

Variations in coronary circulation, cardiac output and heart rate were examined by dopplerography in 14 test subjects kept in an altitude chamber. It was found that during acute hypoxia the effective coronary blood flow decreased distinctly prior to general circulatory disorders. It is recommended to monitor coronary circulation during altitude exposures.

[Evaluation of the hemodynamic indices of a pilot in flight]. / Otsenka nekotorykh pokazatelei gemodinamiki u letchika v polete.

Coronary circulation and systolic and diastolic time intervals were measured in one-seat high-manoeuvrability aircraft pilots during 22 flights. The effective coronary blood flow values varied significantly and reached maximum during landing. In some cases these changes were very large, suggesting a low level of conditioning and physiological reserves. It is recommended to monitor coronary circulation inflight.

[Registration of the heart's magnetic field]. / O registratsii magnitnogo polia serdtsa.

A new magnetometer for the recording of the heart's magnetic field is described in brief. Two constituents of the magnetocardiographic vector were examined in 13 normal male subjects and one coronary patient. In spite of identical sources of potentials and the same type of waves, magneto- and electrocardiograms were shown to differ significantly in terms of wave correlations.

[Reliability of the ultrasonic study of the heart]. / K voprosu o nadezhnosti ul'trazvukovogo issledovaniia serdtsa.

Based on a study of echograms from the heart structures the probabilities of receiving echosignals have been calculated. The probability to detect signals from the endocardium has been shown to be markedly higher than that from the pericardium. Because of great diffusive component of a scattered signal from the endocardium echosignals are reliably received during ultrasonic heart examination.

[Coronary circulation study of a pilot in flight]. / Issledovanie koronarnogo krovoobrashcheniia u letchika v polete.

Coronary circulation was examined in pilots of transport aircraft during 14 flights by Doppler cardiography (with respect to changes in the integrated level of the reflected signal in systole). At certain flight stages the coronary circulation efficiency varied substantially. It is concluded that coronary circulation should be monitored during pilot training and aircraft testing in order to standardize flight loads.

[Diagnosis of fatigue in flight personnel based on cardiodynamic data]. / Diagnostika utomleniia u letnogo sostava po dannym kardiodinamiki.

By Doppler cardiography systolic acid diastolic time time intervals and cardiac contractility were measured in 22 pilots during interflight periods. Certain cardiodynamic parameters showed significant differences in the pilots as compared to 24 nonpilots. It is indicated that these parameters should be regularly monitored between flights in order to prevent fatigue of the flight personnel, to detect early developments of cardiac insufficiency, and maintain pilot longevity.

[Ultrasonic Doppler-cardiography as a method of study of cardiodynamics during flight based on patent and information analysis]. / Ul'trazvukovaia Doppler-kardiografiia kak metod issledovaniia kardiodinamiki v usloviiakh poleta (po materialam patentno-informatsionnogo analiza).

This paper reviews patent and information data on the methods of cardiac location using ultrasound dopplercardiography, as well as on the design and development of onboard equipment to be used for medical monitoring of aircraft and spacecraft crewmembers inflight. It is emphasized that dopplercardiography, being a very informative, noise-proof and relatively simple technique, holds high promise for operational medical monitoring.

[Blood ejection and the phase structure of the cardiac cycle in pilots in flight]. / Issledovanie vybrosa krovi i fazovoi struktury serdechnogo tsikla u letchikov v polete.

Changes in cardiac output and systolic time intervals of pilots inflight were examined by the Doppler ultrasound method. The changes were related to the degree of complexity of different flight stages. It is recommended that the above parameters be monitored during flight training in order to standardize professional loads.

[Potential information value of the ultrasonic Doppler cardiographic method in assessing coronary circulation]. / Ob informativnykh vozmozhnostiakh metoda ul'trazvukovoi doppler-kardiografii v otsenke koronarnogo krovoobrashcheniia.

The use of ultrasonic Doppler cardiography (with respect to the integral values of the signal at systole) to determine efficient coronary circulation was investigated in acute dog experiments (in comparison to the electromagnetic method) and in biophysical models. On the basis of the comparative studies it is concluded that ultrasonic Doppler cardiography can be applied to measure relative changes in the efficient coronary circulation.

[Foreign bodies in the gastrointestinal tract]. / Inorodnye tela zheludochno-kishechnogo trakta.

The authors describe their experience of surgical treatment of 133 patients with foreign bodies in the gastro-intestinal tract under conditions of an urgent twenty-four-hour clinic. A careful clinico-rentgenological and endoscopic examination of patients with foreign bodies in the gastro-intestinal tract in the dynamics of surgical treatment give good results. Special attention was given to the treatment methods (active or actively expecting) of patients with such pathology.

[Possibilities of measuring the dynamics of the stroke volume according to the data of ultrasonic Doppler-cardiography]. / O vozmozhnosti izmereniia dinamiki udarnogo ob'ema krovi po dannym ul'trazvukovoi Doppler-kardiografii

The possibility of determining the relative changes in the stroke volume of the left ventricle on the basis of ultrasonic Doppler-cardiography was studied in animal experiments and in tests with volunteers. The dynamic measurements of the cardiac output by means of ultrasonic Doppler-cardiography were performed on the basis of recording the amplitude of excursions of the posterior wall of the ventricle during the ejection phase by way of integrating the Doppler frequencies in the 150--800 cycles range. Simultaneously the dynamics of the cardiac output was studied electromagnetically (in animal experiments) and rheographically (in volunteers). The results of both the methods correlated closely: the reciprocal correlation coefficient in animal experiments comprised r=0.89 (p less than 0.001), in volunteers r=0.78 (p less than 0.001). The authors concluded that ultrasonic Doppler-cardiography can be used for measuring the relative changes in the stroke volume.