RESUMO
Acitretin over the last 20 years has proven useful in a number of dermatologic diseases. Evidence of efficacy, side-effect profile, and approach to its use will be reviewed.
Assuntos
Acitretina/uso terapêutico , Ceratolíticos/uso terapêutico , Dermatopatias/tratamento farmacológico , Acitretina/farmacologia , Humanos , Ceratolíticos/farmacologia , Ensaios Clínicos Controlados Aleatórios como AssuntoRESUMO
There exists a multitude of medical conditions that cause intractable itch, or pruritus. The successful management of this symptom depends explicitly on establishing the underlying cause. Studies have shown that drugs not traditionally used in the treatment of cutaneous disorders, such as opiate receptor antagonists, antidepressants, and antiepileptics, can provide symptomatic relief of intractable itch. These novel antipruritic agents will be explored in this review.
Assuntos
Prurido/terapia , Anticonvulsivantes/uso terapêutico , Antidepressivos/uso terapêutico , Antipruriginosos/uso terapêutico , Antagonistas dos Receptores Histamínicos H1/uso terapêutico , Humanos , Antagonistas de Entorpecentes/uso terapêutico , FototerapiaRESUMO
Hyperpigmentation disorders of the skin are common and can be the source of significant psychosocial distress for patients. The most common of these disorders are melasma and postinflammatory hyperpigmentation. Sunscreen use and minimizing sun exposure are crucial in all cases. Topical applications are the mainstay of treatment and include phenols, retinoids, corticosteroids, and their combinations.
Assuntos
Fármacos Dermatológicos/uso terapêutico , Hidroquinonas/uso terapêutico , Hiperpigmentação/tratamento farmacológico , Melanose/tratamento farmacológico , Retinoides/uso terapêutico , Administração Tópica , Fármacos Dermatológicos/administração & dosagem , Fármacos Dermatológicos/efeitos adversos , Feminino , Humanos , Hidroquinonas/administração & dosagem , Hidroquinonas/efeitos adversos , Hiperpigmentação/etiologia , Hiperpigmentação/prevenção & controle , Inflamação/complicações , Masculino , Melanose/etiologia , Melanose/prevenção & controle , Retinoides/efeitos adversosRESUMO
Moisturizers are widely used products that are important in many dermatologic and cosmetic skin therapies. They contain varying combinations of emollients, occlusives, and humectants to achieve their beneficial effects, and there is an overwhelming number of formulations available. To develop a rational approach for prescribing moisturizers, commercially available products can be categorized on the basis of application site.