Decline in sperm count in European men during the past 50 years.

PURPOSE: To investigate whether the sperm concentration of European men is deteriorating over the past 50 years of time. MATERIALS AND METHODS: We analysed the data published in English language articles in the past 50 years in altering sperm concentration in European men. RESULTS: A time-dependent decline of sperm concentration ( r = -0.307, p = 0.02) in the last 50 years and an overall 32.5% decrease in mean sperm concentration was noted. CONCLUSION: This comprehensive, evidence-based meta-analysis concisely presents the evidence of decreased sperm concentration in European male over the past 50 years to serve the scientific research zone related to male reproductive health.

Organ Donation: What Are the Opinions of Nursing Students at the University of Bialystok in Poland?

BACKGROUND: Nursing students, as future professionals, have an enormous impact on the opinion of the rest of the population on topics of organ donation and transplantation (ODT). The objective of this study was to analyze the attitudes of nursing students at the University of Bialystok toward ODT, and to determine the factors that affect ithemt. METHODS: Academic year 2011-2012. STUDY POPULATION: nursing students at the University of Bialystok. Type of sampling: sampling points during 5 compulsory-attendance nursing courses with >80% fulfillment. Measuring instrument: validated questionnaire (PCID-ODT Rios) filled out anonymously and self-administered. RESULTS: Completion rate of 90% (331/367): 58% (n = 191) in favor, 35% (n = 118) undecided, and 7% (n = 22) against. The most important variables were: being in the 1st year (odds ratio [OR], 4.444; 95% confidence interval [CI], 11.627-1.700; P = .002); not knowing any donor (OR, 12.048; 95% CI, 55.555-2.57; P = .018); being in favor of organ donation by a relative (OR, 6.25; 95% CI, 14.705-2.666; P < .001); discussing the topic with friends (OR, 2,785; 95% CI, 5.347-1.447; P = .002); not worried about the possible mutilation of the body after donation (OR, 3.039; 95% CI, 5.882-1.569; P = .001); favorable attitude toward ODT of mother (OR, 3.676 (0.881-1.814; P < .001); accepting other treatment options, such as inhumation (OR, 3.436; 95% CI, 7.092-1.655; P = .001); accepting autopsy after death (OR, 2.141; 95% CI, 4.065-1.126; P = .020); and professing the Catholic religion (OR, 3.436; 95% CI, 8.333-1.410; P = .007). CONCLUSIONS: More than 42% of the nursing students were not in favor of organ donation, their attitudes influenced by various psychosocial factors.

Analysis of quality of life of women in menopause period in Poland, Greece, Belarus and Belgium using MRS Scale. A multicenter study.

PURPOSE: The aim of this study was to compare the climacteric symptoms, the activity and quality of life of women in the menopausal period from Poland, Greece, Belarus and Belgium using a Menopause Rating Scale (MRS). MATERIAL AND METHODS: The study was conducted among women over 40 years of age, from Poland (241), Belorussia (119), Greece (100), and Belgium (79). For the purpose of this research, the Polish, Russian, Belgian and Greek versions of the MRS were used. The MRS Scoring scheme is simple, i.e. the score increases point by point with the increasing severity of subjectively perceived symptoms for each of the 11 items (severity 0-no complaints, 4 scoring points-severe). The respondent provides her perception by checking one of 5 possible boxes of "severity" for each of the items. RESULTS: Mild or no complaints were reported to a similar extent by all women from these four countries. The intensity of the psychological symptoms was similar for the studied countries and did not differ significantly (P = 0.1531). Similar results we found in the somatic symptoms among the studied groups (P = 0.1421). A significant difference in the urogenital and sexual symptoms between Belgian and Belorussian women (P<0.001) was found. The frequency of menopausal symptoms was found to be significantly (P = 0.0381) higher among Belgian women in comparison to Belorussian ones. CONCLUSIONS: We found some differences between the menopausal complaints reported by women from Belgium, Belarus, Greece and Poland. Belgian women exhibited a more impaired quality of life due to a higher rate and severity of urogenital and sexual symptoms.

Risk factors for cerebral palsy in term birth infants.

PURPOSE: The aim of this study was to identify the antenatal, intrapartum and neonatal risk factors in term birth infants for cerebral palsy (CP) among babies in a hospital-based study. MATERIALS AND METHODS: The medical records of children with cerebral palsy referred to our Pediatric Rehabilitation Department in Bialystok were reviewed. Antenatal, intrapartum, and neonatal events were compared among 213 children with CP and 280 controls in a retrospective study. We studied live births >36 weeks gestation born between January 1, 1990, and December 31, 2005. RESULTS: Fifty-seven percent of the infants with CP were male. Spastic tetraplegia 78 (36.61%) and spastic hemiplegia 65 (30.51%) were the dominant types of CP. Factors associated with an increased risk of CP identified as antenatal and intrapartum risk factors were pre-eclampsia, abruptio placenta, and placenta previa. Birth asphyxia occurred significantly more often (p<0.001) in children with CP compared to controls. In the neonatal period, respiratory distress syndrome, meningitis and neonatal seizures were associated with an increased incidence of CP. CONCLUSION: Our findings confirm that several antenatal, intrapartum and neonatal risk factors for CP in term birth infants contribute to the etiology of CP.

Indoor air studies of fungi contamination at the Department of Pulmonology and Internal Medicine in Kavala Hospital in Greece.

PURPOSE: The aim of the study was to assess the presence of airborne fungi and the fungal flora of the walls in the Departments of Pulmonary and Internal Medicine in Kavala Hospital (Greece). MATERIAL AND METHODS: The study was carried out at the Department of Pulmonology and Internal medicine in Kavala Hospital. Materials for the tests were: the air samples (in front of the building and the selected rooms) and swabs from the walls. The air pollution was determined using SAS SUPER 100 (Pbi International). The microbial flora from walls was assessed using the Count-Tact applicator and the plate Count-Tact (BioMerieux). Humidity and temperature were evaluated by a thermo-hygrometer. RESULTS: The following fungal pathogens isolated from air were Aspergillus, Candida albicans, Candida spp., and Penicillium species in the Department of Pulmonary. Similar pathogens in the air of Department and Internal Medicine were found. Mean number of fungi colonies isolated from air in the Department of Pulmonology was significantly (p<0.001) higher compared to the Department of Internal Medicine. No significant correlations between CFU of fungi in air and temperature in both Departments were found. CONCLUSIONS: The main fungal pathogens isolated from the air samples were Aspergillus and Candida albicans in the Departments of Pulmonary and Internal Medicine in Kavala Hospital. Fungal occurrence in the air of rooms and walls varied between the both departments of the same hospital.

Analysis of the incidence of fungal pathogens in air of the Department of Dermatology, Venereology and Allergology of Medical University in Wroclaw.

PURPOSE: Analysis of incidence of fungal pathogens in air of Department of Dermatology, Venereology and Allergology of Medical University in Wroclaw. MATERIAL AND METHODS: Materials for the tests were: the air samples in front of the building, corridors, library, lecture hall, and mycological laboratory. The air pollution was determined using SAS SUPER 100. Humidity and temperature were evaluated by a termohigrometr. Classification of the isolated fungi was made with an accordance to the current procedures. RESULTS: From the air was isolated: in library 69 colonies (mean CFU 138 +/- 41.5), from the bookstands--25 colonies (mean CFU-125 +/- 63.6), lecture hall--119 colonies (mean CFU-380 +/- 98.8), mason room--52 colonies (mean CFU-104 +/- 21.9), mycological laboratory--154 colonies (mean CFU-513 +/- 155.3). Temperature in the tested rooms ranged from 24.5 degrees C (mason room) to 26.1 degrees C (library), humidity ranged from 40.1%-53.1%. Temperature outside of the building was 23.6 degrees C, and humidity 51.6%. Moulds Peniciullium citricum and Aspergillus niger and the yeasts Candida albicans were isolated more frequently. CONCLUSIONS: The highest number of fungi colonies were isolated from the air sampled at the lecture hall and mycological laboratory. Moulds were the most common airborne fungi. Temperature and huimidity in the tested rooms are good conditions for the development of fungi.

In vitro antifungal activity of 2,5 disubstituted amino-oksometyloso-arylo-thiadiazole derivatives.

PURPOSE: The aim of the study was the determination of antifungal activity of new of 2,5 disubstituted amino-oksometyloso-arylo-thiadiazole (AOAT) derivatives against Candida albicans, non-Candida albicans. MATERIAL AND METHODS: The determination of antifungal activity AOATs against 20 Candida albicans, 18 non-Candida albicans was performed. Isolates were from different ontocenoses of patients were used for tests. AOATs were synthesized at Department of Chemistry University of Agriculture in Lublin. RESULTS: The mean MIC of AOATs against Candida albicans strains was 141.625 (37.5-200) mg/L on Sabouraud's medium (SB). The mean MIC of AOATs against non-Candida albicans strains was 153.3 (50-200) mg/L. CONCLUSION: It seems that AOATs exert potent antifungal activity against the yeast-like fungi strains in vitro.

Quality of life self-assessment of children living in a children's home, based on own research conducted in the Podlaskie Province.

PURPOSE: The purpose of the study was to diagnose the quality of life (QoL) of children brought up in children's homes, to compare findings with results for peers living in complete families. MATERIAL AND METHODS: In the Stage I was to determine the usefulness of tools for QoL evaluation in a group of 120 children from children's homes in the Podlaskie Province and in a group of 120 children belonging to a control group, brought up in their own families, in the same places where the children's homes were located. Selected research tools were used in Stage II, and the study was carried out in a group of 180 children in the same children's homes and a control group. We used the following survey questionnaires: the standardised CHQ-CF87 survey, standardised KINDL survey and Children's Survey based on WHOQOL-BREF. RESULTS: Significant relationship between the quality of life self-assessment and the place of being brought up for all categories of quality of life was found. A relationship was indicated between the QoL self-assessment and the place of living, age, gender, and physical condition. The charges of a children's home assessed their QoL as significantly lower compared to children living in normal families, mostly in the following categories: health, physical domain and psychological domain, social relations and the ability to function in everyday life. In KINDL survey, strong relationships were found between assessments of QoL categories. CONCLUSIONS: Significant relation between QoL self-assessment and where children were brought up was found. Positive relationship between QoL self-assessment and the place of living, age, gender, and children's physical condition was found.

Relations occurring between health-related behaviour categories and quality of life made by children brought up in a children's home, in the Podlaskie Province.

PURPOSE: The purpose of the study was to determine relations between health-related behaviour categories and quality of life (QoL) categories made by children brought up in a children's home and to compare the results obtained with the results for a group of peers brought up by their own families. MATERIAL AND METHODS: The study was performed on a group of 180 children living in children's homes located in Bialystok, Krasne, Suprasl, Lomza, Nowa Pawlówka; and on a control group of children living with their own families in the same places where children's homes were located. The diagnostic survey method with the Health Behaviour Scale questionnaire, composed of 40 statements defining various behaviours connected with health, and the Children's Questionnaire, based on The World Health Organization Quality of Life (WHOQOL-BREF) was used. RESULTS: Strong correlations between assessments of the Health Behaviour Scale categories and assessments of quality of life categories were found in the group of children living in children's homes, mostly in respect to the relation between health self-assessment and physical activity r = 0.77, mental activity r = 0.74 and environment r = 0.72, and between the physical domain and eating habits r = 0.70, and physical activity and the physical domain r = 0.69. The determination coefficient R2 for the study group had high values for three QoL categories: physical domain 71.5%, mental domain 69.7% and environment 70.1%. CONCLUSIONS: Correlations between Health Behaviour Scale categories and QoL categories were found in the group of children living in children's homes compared to children living with their own families. The relationships for health self-assessment and the physical and mental domains and the environment, and for the physical domain and eating habits and physical activity were found.

A study to ascertain the patients' satisfaction of the quality of hospital care in Greece compared with the patients' satisfaction in Poland.

PURPOSE: The aim of this study is to evaluate the satisfaction of elderly patients, of the hospital care's quality, based on the literature evidence on results of a qualitative research and on a previous developed conceptual frame. MATERIAL AND METHODS: We developed the Elderly Patient Satisfaction Scale (EPSS) by using a combination of qualitative and quantitative research. In this study participated 320 elderly patients from Greece (182 male, 138 female) and 240 patients (136 male, 104 female) from Poland (mean age 74.16 +/- 6.14 years). Most of elderly patients were married. Inclusion criteria were: elderly patients over 65 years old, being able to be interviewed, hospitalized for at least three days and not to be suffering from severe mental disease. RESULTS: There was no correlation among age and global patients' satisfaction. Men in both of groups were expressed greater satisfaction with perceived quality of doctor care than women. Age positively correlated with question who estimate the satisfaction with the time that doctor spends for medical history taking. Patient's education correlated with question (satisfaction with availability of nurses night). Patient's depression found that affects the quality of hospital care and the satisfaction. Elderly patients were most satisfied with the technical care ability of nurse. The time period of hospital stay is correlated negatively with patient's global satisfaction. CONCLUSIONS: No significant difference between the patients from Greece and Poland in majority of dimensions: the satisfaction of elderly patients, of the hospital care's quality was noted.

Comparative analysis of quality of life women in menopause period in Poland, Greece and Belorussia using MRS Scale. Preliminary report.

PURPOSE: The aim of this study was the assessment of climacteric symptoms, the activity and quality of life of women in menopausal period from Poland, Greece and Belorussia using a Menopause Rating Scale (MRS). MATERIAL AND METHODS: The study was conducted among women in age after 45 years, from Poland (55), Belorussia (50) and Greece (85). MRS was obtained from the Professor Heinemann from Center of Epidemiology and Health Studies in Berlin. The scoring scheme is simple, i.e. the score increases point by point with increasing severity of subjectively perceived symptoms in each of the 11 items (severity 0--no complaints, 4 scoring points--severe). The respondent provides her personal perception by checking one of 5 possible boxes of "severity" for each of the items. RESULTS: Mild and no complaints in similar degree were reported by all women from these three countries. We found significant (p < 0.001) differences between severe complaints reported by Greek women compared with complaints respondents from Belorussia and Poland. Moderate complaints were reported more frequently by women from Poland (32.56%) and Belorussia (34%) compared with women from Greece (28.55%). Severe complaints were noted more rarely in 1.6% Greek women compared with 2.6% Belorussian and 3% Polish respondents. No significant differences between no complainants, mild, moderate, marked and severe between women from Belorussia, Poland and Greece. CONCLUSIONS: Generally we did not observe significant differences between reported complaints by women from Belorussia, Poland and Greece.

Quality of life and its relationship to the degree of illness acceptance in patients with diabetes and peripheral diabetic neuropathy.

PURPOSE: Assessment of quality of life, especially from the psychological point of view, is likely to be strongly influenced by the degree of acceptance of one's own illness and the resultant negative emotional reactions associated with the illness itself. The aim of the present study was to determine the relationship between quality of life and the degree of acceptance of illness in diabetic patients with and without peripheral diabetic neuropathy. MATERIAL AND METHODS: 59 patients with diabetes were included in the study; they consisted of patients both with and without peripheral diabetic neuropathy. The degree of acceptance of illness was assessed using the Acceptance of Illness Scale (AIS) and quality of life (HRQOL - health-related quality of life) was measured using the SF-36v2. RESULTS: Quality of life in people with diabetes was reduced and related to their levels of illness acceptance. Factors affecting illness acceptance in patients with peripheral diabetic neuropathy included feelings of being a burden to their family and friends (p < or = 0.05) and the belief that people in their company are made anxious by the patient's illness (p < or = 0.05). These patients also defined their health status as being worse than that of diabetic patients without additional disease complications. CONCLUSIONS: Quality of life and illness acceptance were found to be strongly related. In general, patients with chronic peripheral diabetic neuropathy express lower degrees of acceptance of their illness than diabetic patients without peripheral diabetic neuropathy. Their subjective assessment of health status is also significantly worse than that of diabetic patients without neuropathy.

Indoor air studies of fungi contamination at the Neonatal Department and Intensive Care Unit an Palliative Care in Kavala Hospital in Greece.

PURPOSE: The assessment of the indoor air and walls contamination of fungi at the Kavala Hospital in Greece was made. MATERIAL AND METHODS: The study was carried out at the Neonatal Department and Intensive Care Unit and Palliative Care in Kavala Hospital (Greece). Materials for the tests were: the air samples (in front of the building and the selected rooms) and swabs from the walls. The air pollution was determined using SAS SUPER 100 (Pbi International). The microbial flora from walls was assessed using the Count-Tact applicator and the plate Count-Tact (BioMerieux). Fungi were identified using standard microbial procedures. Classification of isolated fungi was made with an accordance to the current procedures. Humidity and temperature were evaluated by a termohigrometr. RESULTS: The following fungal pathogens isolated from air were Candida albicans, non-Candida albicans, Penicillium species Acremonium, Rhodotorula species, and Aspergillus species. Candida albicans and Penicillium species were dominated fungi in the air of Neonatal Department and Intensive Care Unit. Mean number of fungi colonies isolated from air in the Neonatal Department was significantly (p < 0.001) higher compared to Intensive Care Unit. No significant correlations between CFU of fungi in air and temperature in both Departments were noted. CONCLUSIONS: The main fungal pathogen isolated from the air samples was Candida albicans. No significant differences between number of fungal colonies temperature and humidity of air were found. Further investigations on isolation of the fungal pathogenes from the air samples of operating rooms are needed.

Health-related behaviour self-assessment of children living in a children's home; study based on own research realised in the Podlaskie Province.

PURPOSE: The purpose of the study was to diagnose the health-related behaviour of children brought up in children's homes, to compare the obtained results with those obtained from a group of peers brought up in their own families. MATERIAL AND METHODS: The study group included 180 children living in children's homes in the Podlaskie Province and in a control group composed of children brought up in their own families and living in the same places where the children's homes are located. A questionnaire of the Health Behaviour Scale, composed of 40 statements determining health-related issues was used. RESULTS: Self-assessment of health-related behaviour in the studied youth depended on age, for which a statistical significance was shown for: health self-assessment (p = 0.011), categories of stressful situations (p = 0.047), physical activity (p = 0.028) and social support (p = 0.001); gender, for which a statistical significance was shown for the categories of usage of stimulants (p = 0.000) and place of living, in which the factor "place" was significant (p = 0.000) for all categories; and education, where p = 0.000 for the following categories: stressful situations, using stimulants, physical activity, social support and health self-assessment. Relationships between the categories of health-related behaviour were much stronger in the assessments of the children brought up in children's homes were found. CONCLUSIONS: The self-assessment of health-related behaviour of the studied youth depended on age, gender, place of living and education. Relationships between the categories of health-related behaviour were much stronger in assessments of the children brought up in children's homes as compared to controls.

Exposure the doctors to aggression in the workplace.

PURPOSE: To evaluate the frequency, source and type of aggression towards doctors, depending on their place of work and position. MATERIAL AND METHODS: The study was conducted among 501 doctors from the area of Podlaskie Province. To evaluate the level and type of aggression towards doctors in their workplace we used a questionnaire prepared for the needs of this study by modifying the questionnaire "The frequency and consequences of exposing nurses to workplace aggression", which had been drafted by the Institute of Labour Medicine in Lódz. The results were analysed with the application of the chi-square and the Kruskal-Wallis tests. RESULTS: The most common form of aggression was voice raising, which happened to 80% of doctors employed in inpatient medical centres and 91% doctors from outpatient centres. More than a half of the subjects have heard threats from their patients. Verbal aggression from doctors' superiors happened most often in surgery wards (48%), neurology wards (40%), admission rooms (33%). The causes of aggression most often quoted by doctors include: staff shortages (9%), stress--tiredness (9%). CONCLUSIONS: Workplace aggression towards doctors may be inflicted both by patients and colleagues. The aggression in the medical environment can take on different forms and create a threat in the workplace. Doctors working in hospital wards (psychiatry, surgery, neurology) are the ones who are the most exposed to aggression.

Nursing problems of patients with systemic sclerosis.

UNLABELLED: Systemic sclerosis (SSc) is a chronic autoimmune disease connective tissue and one of the most common collagen diseases. There are several clinical types of scleroderma which differ in their course, possible complications and prognosis. The most characteristic form SSc is limited and diffuse systemic sclerosis. The SSc is characterized by the progressive fibrosis of the skin and internal organs, leading to their failure, morphology and blood vessels disorders. PURPOSE: The aim of our work is to identify the main health problems of patients suffering from systemic sclerosis depending on its clinical form: limited systemic sclerosis (ISSc) and diffuse systemic sclerosis (dSSc); to determine the influence of disease duration on symptom intensification in patients with LSSc and dSSc. MATERIAL AND METHODS: The study group consisted of 63 patients with systemic sclerosis diagnosed according to the criteria of the American Rheumatism Association (ARA), 47 of whom had limited systemic sclerosis (ISSc) (74.6%) and 16--diffuse systemic sclerosis (dSSc) (25.4%). CONCLUSIONS: The key thing in the complex therapy is to recognize the individual care problems of the patient, to assess his ability to cope with the disease in daily life and to plan care, support, education and help of other professionals. The main aim of individual nursing care is to alleviate ailments, prevent infections, observe life-threatening conditions and to educate the patient as regards self-care and self-observation.

Variations of enzymatic activity and biotypes of the yeast like fungi strains isolated from cancer patients.

PURPOSE: Determination of the enzymatic activity and enzymatic biotypes variations of the yeast like fungi strains isolated from cancer patients with oral candidiasis during last 5 years. MATERIAL AND METHODS: We evaluated enzymatic activity of 92 Candida albicans strains isolated from oral ontocenosis from cancer patients with candidiasis symptoms in 1999 and 2003. The enzymatic activity of the strains tested was assessed by the API ZYM (bioMerieux) method. Biotypes of the strains were determined according to Williamson's or Kurnatowska's and Kurnatowski's classifications. RESULTS: In 1999 Candida albicans 17 of 19 tested isolates had hydrolytic activity hydrolases and 87% of strains were assigned according to Wiliamson's. Only 8.7% of strains were classified according to Kurnatowska's and Kurnatowski's, but 4.3% strains according to Krajewska-Kulak et al. In 2003, 18 of 19 strains had hydrolytic activity and 93.5% of strains were classified according to Wiliamson's, but 4.3% according to Kurnatowska's and Kurnatowski's and 2.2% according to Krajewska-Kulak et al. CONCLUSIONS: The results of present study indicate that most of tested strains were classified into Wiliamson's system. Our findings suggest that other Candida biotypes should be determined according to their different enzymatic activity and susceptibilities.

In vitro antifungal activity of N-3-(1,2,4-dithiazole-5-thione)-beta-resorcylcarbothioamide.

The aim of the study was the determination of antifungal activity of N-3-(1,2,4-dithiazole-5-thione)-beta-resorcylcarbothioamide (DTRTA) against Candida albicans, non-Candida albicans, dermatophytes and molds and evaluation of the enzymatic activity C. albicans strains. We used reference strains C. albicans 10231 ATCC, 200 of C. albicans strains, 7 of non-C. albicans, 12 dermatophytes strains and 20 molds strains isolated from different ontocenoses from patients. DTRTA was synthesized at Department of Chemistry University of Agriculture in Lublin was used to tests. The mean MIC of DTRTA against C. albicans strains isolated from patients was 22.01 mg/L, for reference C. albicans 10231 ATCC-- 12.5 mg/L on Sabouraud's medium (SB). The mean MIC of isolates from patients was 17.8 mg/L, and reference strains--6.25 mg/L on YNB medium, respectively. The MICs of DTRTA against 7 non-C. albicans was 33 mg/L on SB and 18.2 mg/L on YNB. The MICs of DTRTA against dermatophytes ranged from 3 to 50mg/L. The MICs of DTRTA against molds were 25 mg/L and 100 mg/L, respectively. C. albicans strains had the enzymatic activity of 16 among 19 hydrolases, after exposure to DTRTA, 15 among 19 enzymes, respectively. Non-C. albicans isolates had the enzymatic activity of 13 among 19 hydrolases, after exposure to DTRTA, 11 among 19 enzymes, respectively. This findings indicate hat DTRTA exerts a potent antifungal activity against the yeast-like fungi strains, dermatophytes and molds in vitro and.

Indoor air studies of fungi contamination of social welfare home in Czerewki in north-east part of Poland.

PURPOSE: The contamination of the indoor environment with yeast-like fungi and moulds in social welfare home in Czerewki was evaluated. MATERIAL AND METHODS: The concentration of airborne fungi (in front of the building and in the corridors, patient rooms, study rooms, recreation rooms, kitchens, bathrooms, toilets) was determined using SAS-Super 100 (Pbi International). The fungal concentration on walls was assessed using the Count-Tact applicator and the plate Count-Tact irradiated (BioMerieux). Swabs were taken from the skin of the interdigital spaces of feet and hands, nails and the oral cavity of the residents. The fungi from the swabs were cultured on Sabouraud medium. Fungi were identified using standard microbial procedures. RESULTS: Tests of air and walls revealed significant differences in mycological flora in depending on the place isolation (e.g. corridor, rooms, reading room, nurse, room, kitchen, dining room, bathroom) and season (summer, autumn, winter, spring). A significant increase in the fungi isolated from the air and walls in the social welfare home was found, depending on the season. CONCLUSION: An increase in the fungi isolated from residents was found in relation to the season.