[Interferon-inducing activity of poly(I)-poly(C) and its complexes with polycations and their resistance to enzymatic degradation]. / Interferonindutsiruiushchaia aktivnost' poli(I)-poli(Ts) i ego kompleksov s polikationami i ikh ustoichivost' k fermentativnomu razrusheniiu.

The insoluble complexes of poly (I) . poly (C) with histones and poly-L-lysin have been obtained. These complexes are insoluble in isotonic solutions and have no admixtures of polycations. Resistance to enzymatic degradation, the melting point and sorption on the cells of the complexes obtained increase with the growth of the polycation amount in the complexes, while the interferon-inducing capacity reduces. Based on the obtained and reported data the conclusion is made that resistance to enzymatic degradation, the high melting point and the high sorption of the inductor on the cells are necessary but insufficient conditions for the induction of interferon synthesis. It is assumed that the inductor ability to make complexes with cellular proteins is the characteristics responsible for the interferon-inducing capacity of the inductor.

[Experimental basis for using Soviet bentonite clays as immunosorbents for serological studies]. / Eksperimental'noe obosnovanie ispol'zovaniia otechestvennykh bentonitovykh glin v kachestve immunosorbentov dlia serologicheskikh issledovanii.

The methodological principles of using Soviet bentonite clays as immunosorbents necessary for serological studies in bacterial infections were worked out. The method for the preparation of antigenic bentonite diagnostic reagents was experimentally substantiated. Bentonite diagnostic reagents were first used in a new method for the rapid indication of bacterial antigens in environmental objects with a view of solving epidemiological problems.