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1.
J Neurol Surg A Cent Eur Neurosurg ; 84(5): 428-432, 2023 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-35062035

RESUMO

BACKGROUND: Surgical treatment of anterior cranial base traumatic cerebrospinal fluid (CSF) rhinorrhea is challenging and is fraught with complications. Whether a person should be offered open craniotomy or endoscopic endonasal repair is a dilemma faced by most surgeons. This study is one of the few to directly compare the two forms of management. METHODS: Data were collected from two groups of 15 patients each who underwent transcranial CSF leak repair and endoscopic endonasal CSF leak repair in a tertiary care hospital over a 3-year period. Information including demographics, recurrence rates, complications, and hospital and intensive care unit (ICU) stay was recorded and analyzed. Outcome was assessed up to 6 months. RESULTS: Recurrence was seen in 9/30 patients, 6 in the transcranial group and 3 in the endoscopic group. Hospital stay was longer than 1 week in all the transcranially operated patients and only in 73% of the endoscopically operated patients (p = 0.439) although ICU stay was reduced in the endoscopic group (p = 0.066). Complications were more common with transcranial repair (seven of eight patients who underwent transcranial repair, p = 0.035) with anosmia being the most common (33.3%, p = 0.042). CONCLUSION: The transcranial open repair is a reasonable choice especially for leaks that occur through the frontal sinus and extend backward into the frontoethmoidal region. However, this approach has the drawbacks of greater number of complications, higher recurrence rate, and longer ICU and overall hospital stay. The endoscopic endonasal repair enjoys a lower morbidity profile although it may not be an adequate treatment for leaks that are placed far laterally in the frontal sinus.


Assuntos
Rinorreia de Líquido Cefalorraquidiano , Humanos , Rinorreia de Líquido Cefalorraquidiano/etiologia , Rinorreia de Líquido Cefalorraquidiano/cirurgia , Vazamento de Líquido Cefalorraquidiano , Endoscopia/efeitos adversos , Base do Crânio/cirurgia , Craniotomia/efeitos adversos , Estudos Retrospectivos , Resultado do Tratamento
2.
Neurol India ; 59(3): 443-6, 2011.
Artigo em Inglês | MEDLINE | ID: mdl-21743180

RESUMO

Rosai Dorfman disease (RDD), also known as sinus histiocytosis with massive lymphadenopathy, is a benign histiocytic proliferative disorder mainly affecting the lymph nodes. Although several cases of extra-nodal involvement have been reported previously, central nervous system involvement, particularly in the absence of nodal disease is extremely rare. We report a case of isolated intracranial RDD occurring in a relatively elder patient, which was shown by histological examination to have a dura-based involvement.


Assuntos
Doenças do Sistema Nervoso Central/patologia , Histiocitose Sinusal/patologia , Anti-Inflamatórios/uso terapêutico , Doenças do Sistema Nervoso Central/tratamento farmacológico , Dura-Máter/patologia , Transtornos Neurológicos da Marcha/etiologia , Transtornos Neurológicos da Marcha/patologia , Histiócitos/patologia , Histiocitose Sinusal/tratamento farmacológico , Humanos , Imageamento por Ressonância Magnética , Masculino , Pessoa de Meia-Idade
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