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2.
Surg Endosc ; 36(2): 1476-1481, 2022 02.
Artigo em Inglês | MEDLINE | ID: mdl-33825012

RESUMO

PURPOSE: To investigate driving ability (brake reaction time, BRT) after right-sided hernia repair. It was assumed that postoperatively BRT would be impaired as compared to the preoperative reference and healthy controls. METHODS: BRT was prospectively collected from 30 patients undergoing hernia repair [Lichtenstein or total extraperitoneal endoscopic procedure (TEP)]. BRT was measured with a driving simulator preoperatively and on postoperative days 2 and 14. After receiving a visual stimulus, the patients had to apply the brake pedal with 160 N. The average of ten runs was used as the patient's BRT value. RESULTS: Thirty patients completed all measurements. In the Lichtenstein group, BRT was significantly impaired as compared to the patient's preoperative values (p = 0.021). Two weeks after surgery BRT had returned to the preoperative level (p = 0.859). BRT in the Lichtenstein group was also significantly impaired 2 days postoperatively as compared to the BRT of 60 healthy controls (p = 0.001). In the TEP group, no impaired BRT was detected. CONCLUSIONS: Based on our finding of significantly impaired BRT in patients following right-sided Lichtenstein hernia repair, it seems wise to recommend that such patients refrain from driving for 2 weeks after surgery. No such impairment was found in patients following TEP surgery. Consequently, it is deemed safe for them to resume driving 2 days after the procedure.


Assuntos
Condução de Veículo , Hérnia Inguinal , Hérnia Inguinal/cirurgia , Herniorrafia/métodos , Humanos , Período Pós-Operatório , Tempo de Reação
3.
Arch Orthop Trauma Surg ; 142(10): 2497-2501, 2022 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-33768277

RESUMO

INTRODUCTION: To retrospectively investigate the early postoperative range of motion (ROM) (days 4, 7, 10) after total knee arthroplasty (TKA) and to test for associations (a) with long-term outcome in terms of ROM and (b) with a disease-specific knee score. MATERIALS AND METHODS: A retrospective analysis was performed in patients with previous primary TKA. Data taken from the medical records were ROM from preoperative and postoperative days 4, 7 and 10 and 1 year. As patient-reported outcome the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC Score) was taken from preoperative and one year after TKA. RESULTS: 316 patients (330 knees) were available. Only negligible correlations were determined between ROM at twelve months postoperative and ROM in the early postoperative days (days 4, 7, 10). Similarly, only negligible correlations were determined between ROM in the early postoperative days (days 4, 7, 10) and the 1-year WOMAC. CONCLUSION: From the main findings it would seem that steepness of ROM ascent in the early postoperative days is of minor importance for (a) long-term ROM and (b) long-term knee score outcome after TKA.


Assuntos
Artroplastia do Joelho , Osteoartrite do Joelho , Humanos , Articulação do Joelho/cirurgia , Osteoartrite do Joelho/cirurgia , Amplitude de Movimento Articular , Estudos Retrospectivos , Resultado do Tratamento
4.
Knee Surg Sports Traumatol Arthrosc ; 30(9): 3162-3167, 2022 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-33934185

RESUMO

PURPOSE: To determine whether preoperative radiologic joint space width (JSW) is related to the outcome of medial unicondylar knee arthroplasty (UKA) (primary hypothesis). METHODS: A retrospective comparative analysis was performed. One group was comprised of UKA patients with preoperative JSW 0-1 mm. Another group was made up of patients with preoperative JSW ≥ 2 mm (range 0-4 mm). The JSW was measured from preoperative weight-bearing Schuss-view radiographs. The clinical outcome was determined with the Western Ontario and MacMaster Universities (WOMAC) Osteoarthritis Index score preoperatively and 1 year after medial UKA. Implant survival data were obtained from the arthroplasty register of Tyrol. RESULTS: There were 80 patients with a preoperative JSW 0-1 mm (age 66, BMI 27.8) and 70 patients with a preoperative JSW ≥ 2 mm (age 64, IQR 15, BMI 28.1). WOMAC total was 10 ± 10 in patients with 0-1 mm JSW and 25 ± 47 in patients with ≥ 2 mm JSW at 1 year postoperative (p = 0.052). WOMAC pain at 1 year postoperative was 7 ± 16 in patients with 0-1 mm JSW and 18 ± 46 in patients with ≥ 2 mm JSW (p = 0.047). WOMAC function at 1 year postoperative was 10 ± 9 in patients with 0-1 mm JSW and 17 ± 51 in patients with ≥ 2 mm JSW (p = 0.048). In patients with 0-1 mm JSW 5 year prosthesis survival was 92.3% and in patients with ≥ 2 mm JSW, it was 81.1% (p = 0.016). CONCLUSIONS: In patients with preoperative complete joint space collapse (0-1 mm JSW), clinical outcome was superior to that of patients with incomplete joint space collapse. This was true for both 1 year postoperative WOMAC pain and WOMAC function and for 5 year implant survival rates. On the basis of our findings, it is recommended that 'complete joint space collapse' especially be used to achieve best clinical outcome in medial UKA surgery. LEVEL OF EVIDENCE: IV.


Assuntos
Artroplastia do Joelho , Osteoartrite do Joelho , Idoso , Humanos , Articulação do Joelho , Pessoa de Meia-Idade , Dor Pós-Operatória , Estudos Retrospectivos , Resultado do Tratamento
5.
Bone Joint J ; 103-B(3): 536-541, 2021 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-33641409

RESUMO

AIMS: The aim of this retrospective study was to compare the correction achieved using a convex pedicle screw technique and a low implant density achieved using periapical concave-sided screws and a high implant density. We hypothesized that there would be no difference in outcome between the two techniques. METHODS: We retrospectively analyzed a series of 51 patients with a thoracic adolescent idiopathic scoliosis. There were 26 patients in the convex pedicle screw group who had screws implanted periapically (Group 2) and a control group of 25 patients with bilateral pedicle screws (Group 1). The patients' charts were reviewed and pre- and postoperative radiographs evaluated. Postoperative patient-reported outcome measures (PROMs) were recorded. RESULTS: The number of implants (14.5 vs 17.1) and the implant density (1.5 vs 1.9) were significantly lower in Group 2 (p < 0.001). Operating time was 27 minutes shorter in Group 2 than in Group 1, with a mean of 217 minutes (SD 50.5; 120 to 346). The duration of surgery per instrumented vertebra was reduced by 19% in Group 2 (p = 0.011). No statistical difference was found in the postoperative Cobb angle, vertebral rotation, the relative correction achieved, or postoperative PROMs. CONCLUSION: Despite a lower implant density and achieving correction through a convex rod, surgical correction of the Cobb angle and vertebral body rotation was similar in both groups. Periapical pedicle screws and primary correction on the concave side do not seem to be mandatory in order to achieve good surgical results in idiopathic thoracic scoliosis. The operating time was shorter in the group with lower implant density. In conclusion, the technique provided good results and has the potential to reduce complications and costs. Cite this article: Bone Joint J 2021;103-B(3):536-541.


Assuntos
Parafusos Pediculares , Escoliose/cirurgia , Fusão Vertebral/instrumentação , Adolescente , Feminino , Humanos , Masculino , Medidas de Resultados Relatados pelo Paciente , Desenho de Prótese , Estudos Retrospectivos , Inquéritos e Questionários
6.
Orthopade ; 50(8): 674-680, 2021 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-33575812

RESUMO

BACKGROUND: The aim of the study was to investigate the issue of medial midvastus (MMV) vs. medial parapatellar (MPP) approaches in total knee arthroplasty (TKA). It was hypothesized that the two surgical approaches would produce significantly different results with respect to patient-reported knee score outcome (hypothesis 1), short-term postoperative range of motion (ROM) (hypothesis 2), long-term postoperative ROM (hypothesis 3) and prosthesis survival (hypothesis 4). METHODS: A retrospective comparative study design was applied. Data sets were obtained from the state arthroplasty registry. The Western Ontario and McMaster Universities osteoarthritis index (WOMAC) data were analyzed from preoperative and 1 year postoperatively. The ROM data were analyzed for the time points preoperative, postoperative days 4 and 10 and 1 year. RESULTS: Available were 627 cases (407 MMV vs. 220 MPP) and 1 year postoperatively there were no significant differences between groups regarding the WOMAC scores (hypothesis 1). Early postoperatively on days 4 and 10 after TKA there were no differences between groups (p = 0.305 and p = 0.383, respectively, hypothesis 2). Likewise, ROM did not significantly differ between the groups 1 year after TKA (p = 0.338, hypothesis 3). The 5­year prosthesis survival did not differ between the groups and showed 94.46% (95% confidence interval, CI 90.69-96.73%) in the MMV group and 94.33% (95% CI 89.96-96.83%) in the MPP group (p = 0.664, hypothesis 4). CONCLUSION: Both surgical approaches produce equivalent clinical results in terms of early postoperative ROM, late postoperative ROM and 1­year WOMAC. The same prosthesis survival rates can be expected.


Assuntos
Artroplastia do Joelho , Prótese do Joelho , Osteoartrite do Joelho , Humanos , Articulação do Joelho/cirurgia , Osteoartrite do Joelho/cirurgia , Amplitude de Movimento Articular , Estudos Retrospectivos , Resultado do Tratamento
7.
Arch Orthop Trauma Surg ; 140(4): 545-549, 2020 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-32100107

RESUMO

PURPOSE: It was the aim of our study to compare the functional outcome (WOMAC score, range of motion) achieved with unicondylar knee arthroplasty (UKA) and total knee arthroplasty (TKA). It was hypothesized that UKA and TKA would differ with regard to the WOMAC function scale (hypothesis 1) and the WOMAC total scale (hypothesis 2). It was assumed that the groups would differ with respect to changes in range of motion (ROM) over time (hypothesis 3). METHODS: A retrospective comparative study was conducted to analyze data available from the federal state's Arthroplasty Registry (WOMAC score) and from clinical routine (ROM). Patients who underwent UKA or TKA between 2008 and 2015 were considered. ANOVAs for repeated measurements were applied, adjusted for age, to test hypotheses 1-3. RESULTS: The UKA group was comprised of 112 patients (age 65, BMI 29). The TKA group included 330 cases (age 69, BMI 29). Regarding hypothesis 1, the amount of improvement in WOMAC function was not influenced by the surgical group (no significant group*time interactions, p = 0.608). Similarly, for hypothesis 2, the amount of improvement in the WOMAC total score was not influenced by the surgical group (no significant group*time interactions, p = 0.392). Regarding hypothesis 3, we found no significant group*time interaction for the ROM data (p = 0.731). CONCLUSIONS: On the basis of our findings, it is concluded that whether knee osteoarthritis is treated with either medial UKA or TKA has no influence on the WOMAC total score or any of the WOMAC subscales. It has no effect on early or late ROM gain.


Assuntos
Artroplastia do Joelho , Osteoartrite do Joelho , Idoso , Artroplastia do Joelho/efeitos adversos , Artroplastia do Joelho/métodos , Artroplastia do Joelho/estatística & dados numéricos , Humanos , Joelho/fisiopatologia , Joelho/cirurgia , Pessoa de Meia-Idade , Osteoartrite do Joelho/fisiopatologia , Osteoartrite do Joelho/cirurgia , Amplitude de Movimento Articular/fisiologia , Estudos Retrospectivos , Resultado do Tratamento
8.
J Arthroplasty ; 34(10): 2449-2453, 2019 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-31186184

RESUMO

BACKGROUND: Periprosthetic femoral fractures (PFFs) after total hip arthroplasty are devastating complications often resulting in functional limitations and increased mortality. The use of the direct anterior approach (DAA) is becoming more popular, and the number of revisions done through this interval is increasing. The DAA interval can be expanded to treat PFFs. This retrospective case series assessed outcomes of PFF patients treated with the extension of the DAA interval. METHODS: The study contained 40 patients (40 hips). Mean patient age was 74.3 years (range, 55.1-92.2 years). Mean follow-up time was 50.4 months (range, 20-98.2 months). Fractures were classified as Vancouver B2 (n = 36) and B3 (n = 4). RESULTS: Median cut-to-close time was 152 minutes (interquartile range: 80-279). There were five complications (12.5%): 2 deaths, 1 transient femoral nerve palsy, 1 fissure distal to the stem, and 1 hematoma. CONCLUSION: Expansion of the DAA interval to treat PFF showed similar results compared with other surgical approaches in terms of mortality, complications, fracture healing, and dislocation rate. These results indicate that femoral revision for PFF in the DAA interval is a safe and reliable procedure compared with other surgical approaches for the treatment of Vancouver B2 and B3 periprosthetic fractures.


Assuntos
Artroplastia de Quadril/métodos , Fraturas do Fêmur/cirurgia , Fraturas Periprotéticas/cirurgia , Idoso , Idoso de 80 Anos ou mais , Artroplastia de Quadril/efeitos adversos , Feminino , Fêmur/cirurgia , Seguimentos , Fixação Interna de Fraturas/métodos , Consolidação da Fratura , Humanos , Tempo de Internação , Masculino , Pessoa de Meia-Idade , Reoperação/efeitos adversos , Estudos Retrospectivos
9.
J Neurosurg Spine ; 31(1): 15-19, 2019 03 15.
Artigo em Inglês | MEDLINE | ID: mdl-30875684

RESUMO

OBJECTIVE: The positive effect of primary lumbar disc surgery on braking reaction time (BRT) has already been shown. The authors investigated the effect of recurrent lumbar disc herniation surgery on BRT. METHODS: Twenty-four patients (mean age 49.9 years) were investigated for BRT 1 day before surgery, postoperatively before hospital discharge, and 4 to 5 weeks after surgery. Thirty-one healthy subjects served as a control group. RESULTS: Significant improvement of BRT following surgery was found in all patients (p < 0.05). For patients with right-sided recurrent disc herniation, median BRT was 736 msec before surgery, 685 msec immediately postoperatively, and 662 msec at follow-up. For patients with left-sided recurrent disc herniation, median BRT was 674 msec preoperatively, 585 msec postoperatively, and 578 msec at follow-up. Control subjects had a median BRT of 487, which differed significantly from the patient BRTs at all 3 test times (p < 0.05). CONCLUSIONS: A significant reduction in BRT in patients with recurrent disc herniation was found following lumbar disc revision surgery, indicating a positive impact of surgery. Due to the improvement in BRT observed immediately after surgery, we conclude that it is appropriate to recommend that patients keep driving after being discharged from the hospital.


Assuntos
Condução de Veículo , Deslocamento do Disco Intervertebral/cirurgia , Feminino , Seguimentos , Humanos , Deslocamento do Disco Intervertebral/fisiopatologia , Vértebras Lombares/cirurgia , Masculino , Pessoa de Meia-Idade , Tempo de Reação , Recidiva , Resultado do Tratamento
10.
Int Orthop ; 43(8): 1841-1847, 2019 08.
Artigo em Inglês | MEDLINE | ID: mdl-30276450

RESUMO

AIM OF THE STUDY: To determine if pre-operative radiologic minimal joint space width (mJSW) is related to the outcome of total knee arthroplasty (TKA) (primary hypothesis). Likewise, the aim was to test if pre-operative mJSW is related to prosthesis survival (secondary hypothesis). METHODS: A retrospective comparative analysis was performed. Group 1 was comprised of patients with pre-operative mJSW 0-1 mm. Group 2 were patients with pre-operative mJSW ≥ 2 mm. The clinical outcome was determined with the Western Ontario and MacMaster Universities Osteoarthritis Index (WOMAC) score pre-operatively and one year after TKA. Only patients with pre-operative weight-bearing radiographs and complete WOMAC score data were accepted. RESULTS: Available for analysis were 377 patients, of whom 188 were allocated to Group 1 (118 female, 70 male, age 70 ± 11 years) and 189 to Group 2 (118 female, 71 male, age 70 ± 13 years). Pre-operative WOMAC total and WOMAC subscores showed no significant differences between groups. Post-operatively, the WOMAC total was significantly better in Group 1 than in Group 2, 10 ± 22 and 19 ± 31, respectively (p < 0.001, Power 97.5%). Similarly, the WOMAC subscores for pain, stiffness, and function were also significantly better in Group 1 than in Group 2. Five-year prosthesis survival was 94.2 and 91.6% in Groups 1 and 2, respectively (p = 0.07, Power 71%). DISCUSSION: Patients with pre-operative complete joint space collapse (0 to 1 mm mJSW) achieve a significantly better WOMAC result from TKA than do those with a mJSW equal to or greater than 2 mm. From our findings, it is recommended that "complete joint space collapse" especially be used as an indication for TKA surgery. CONCLUSION: Our study was underpowered to sufficiently show an effect of pre-operative mJSW on prosthesis survival.


Assuntos
Artroplastia do Joelho , Articulação do Joelho/diagnóstico por imagem , Articulação do Joelho/cirurgia , Osteoartrite do Joelho/diagnóstico por imagem , Osteoartrite do Joelho/cirurgia , Satisfação do Paciente , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos
11.
Int Orthop ; 43(7): 1583-1590, 2019 07.
Artigo em Inglês | MEDLINE | ID: mdl-30097730

RESUMO

PURPOSE: Occult intra-operative periprosthetic acetabular fracture is a seldom-reported complication of primary total hip arthroplasty (THA). It may potentially be associated with cup instability and implant loosening. The present study aimed to investigate clinical consequences of this complication. METHODS: Between 2003 and 2012, a total of 3390 cementless total hip arthroplasties (THA) were performed at our institution. Their medical histories were retrospectively reviewed to identify all patients who received a thin-layer computer tomography (CT) scan of the pelvis including the acetabulum within the first 30 post-operative days. They were evaluated and classified by two radiologists independently with respect to the presence of recent acetabular fractures. All cases with acetabular and periacetabular fractures were included in this study. Electronic medical records were reviewed to assess implant revision. Cup stability was measured with EBRA (Einzel-Bild-Röntgen-Analyse) from plain X-rays. RESULTS: Periprosthetic fractures of the acetabulum were identified in 58 (50.4%) of 115 selected patients. Fractures close to but not including the acetabulum were identified in 45% (n = 26/58) of the patients, at the superolateral wall in 17% (n = 10/58), at the anterior wall of the acetabulum in 16% (n = 9/58) and in 10% (n = 6/58) each at the medial wall, and at the posterior wall respectively. One out of these 58 fractures could not be classified. Three of a total of six occult medial wall fractures had to be revised, and another two showed a high implant migration. The highest cup migration values however were found after fractures of the superolateral wall. Incomplete column fractures did not influence implant survival. CONCLUSION: Central wall acetabular fractures, although unrecognized intra- and post-operatively may impair implant survival after THA.


Assuntos
Acetábulo/lesões , Artroplastia de Quadril/efeitos adversos , Fraturas Ósseas/etiologia , Prótese de Quadril/efeitos adversos , Fraturas Periprotéticas/etiologia , Falha de Prótese/etiologia , Acetábulo/cirurgia , Idoso , Artroplastia de Quadril/instrumentação , Feminino , Fraturas Ósseas/diagnóstico por imagem , Fraturas Fechadas/diagnóstico por imagem , Fraturas Fechadas/etiologia , Humanos , Complicações Intraoperatórias/etiologia , Masculino , Pessoa de Meia-Idade , Fraturas Periprotéticas/diagnóstico por imagem , Estudos Retrospectivos , Tomografia Computadorizada por Raios X
12.
BMC Musculoskelet Disord ; 19(1): 388, 2018 Oct 30.
Artigo em Inglês | MEDLINE | ID: mdl-30376863

RESUMO

BACKGROUND: Myofascial trigger points (MTrPs) are hyperirritable areas in the fascia of the affected muscle, possibly related to mitochondrial impairment. They can result in pain and hypoxic areas within the muscle. This pilot study established a minimally invasive biopsy technique to obtain high-quality MTrP tissue samples to evaluate mitochondrial function via high-resolution respirometry. Secondary objectives included the feasibility and safety of the biopsy procedure. METHODS: Twenty healthy males participated in this study, 10 with a diagnosis of myofascial pain in the musculus (m.) trapezius MTrP (TTP group) and 10 with a diagnosis of myofascial pain in the m. gluteus medius (GTP group). Each participant had 2 muscle biopsies taken in one session. The affected muscle was biopsied followed by a biopsy from the m. vastus lateralis to be used as a control. Measurements of oxygen consumption were carried out using high-resolution respirometry. RESULTS: Mitochondrial respiration was highest in the GTP group compared to the TTP group and the control muscle whereas no differences were observed between the GTP and the control muscle. When normalizing respiration to an internal reference state, there were no differences between muscle groups. None of the participants had hematomas or reported surgical complications. Patient-reported pain was minimal for all 3 groups. All participants reported a low procedural burden. CONCLUSIONS: This pilot study used a safe and minimally invasive technique for obtaining biopsies from MTrPs suitable for high-resolution respirometry analysis of mitochondrial function. The results suggest that there are no qualitative differences in mitochondrial function of MTrPs of the trapezius and gluteus medius muscles compared to the vastus lateralis control muscle, implying that alterations of mitochondrial function do not appear to have a role in the development of MTrPs. TRIAL REGISTRATION: Registered as No. 20131128-850 at the Coordinating Center for Clinical Studies of the Medical University of Innsbruck, trial registration date: 28th November 2013 and retrospectively registered on 11th of October 2018 at ClinicalTrials.gov with the ID NCT03704311 .


Assuntos
Mitocôndrias/fisiologia , Síndromes da Dor Miofascial/diagnóstico , Síndromes da Dor Miofascial/metabolismo , Consumo de Oxigênio/fisiologia , Músculos Superficiais do Dorso/metabolismo , Músculos Superficiais do Dorso/patologia , Adulto , Biópsia por Agulha/métodos , Nádegas , Estudos de Coortes , Humanos , Masculino , Pessoa de Meia-Idade , Projetos Piloto , Estudos Prospectivos , Adulto Jovem
13.
J Surg Educ ; 75(6): 1643-1649, 2018 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-29929818

RESUMO

OBJECTIVE: Knee arthroscopies are very common orthopedic procedures. For a number of reasons, including increased public awareness for medical errors, patient safety, strict regulations governing duty-hours for residents, surgeons' liability, and an increasing emphasis on the efficient use of operating room time, interest in simulator training is on the rise. It was the purpose of this study to analyze learning curves of medical students and orthopedic resident surgeons using a virtual knee arthroscopy simulator. DESIGN: Learning curves of medical students and orthopedic residents were measured perspective using an arthroscopic training simulator for 2 different exercises. Time, camera and probe movement as well as camera and probe roughness were the parameters to be compared. Mean and standard deviation of the initial and the final score for the consecutively performed exercises as well as their slope were reported. SETTING: The study was performed at the Medical University of Innsbruck, Department of Orthopaedic Surgery. Level of clinical care: institutional. PARTICIPANTS: A Students Group (n = 10) consisting of medical students at the Medical University of Innsbruck with no prior knowledge of arthroscopy but interest in orthopedic surgery was selected. The group was compared to a Residents Group (n = 9) which was comprised of orthopedic resident surgeons who had learned arthroscopy in operation courses. All participants involved in the study did several repetitions of the described exercises. RESULTS: Both groups improved their skills after several repetitions. Residents were on average faster, moved the camera less, and touched the cortical tissue less than the students. For certain parameters students showed a steeper improvement curve than did residents, because the students started from a different experience level. CONCLUSIONS: In conclusion, our results demonstrate the usefulness of virtual knee arthroscopy simulators as an important tool for improving surgical and arthroscopic skills in orthopedic resident surgeons, and medical students.


Assuntos
Artroscopia/educação , Competência Clínica , Internato e Residência/métodos , Internato e Residência/normas , Articulação do Joelho/cirurgia , Curva de Aprendizado , Procedimentos Ortopédicos/educação , Treinamento por Simulação , Estudos Prospectivos
14.
Arch Orthop Trauma Surg ; 138(1): 99-103, 2018 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-29079909

RESUMO

INTRODUCTION: In light of inconsistencies in the literature, this study aimed to investigate the relationship between obesity (current and historic) and osteoarthritis (OA) of the knee or hip. MATERIALS AND METHODS: We examined 99 people (knee OA, hip OA and controls), age > 50 years, in a case-control study. The current weight, height and waist circumference were measured on site, and detailed weight changes over their lifetime were based on questionnaires and standardized interviews. We used binomial logistic regression to determine the predictive value for an osteoarthritis group membership of each derived indicator. RESULTS: An increase in 'maximum-BMI' increased the odds ratio for both knee OA (OR 1.2; CI 1.1-1.4; p = 0.005; R 2 = 0.36) and hip OA (OR 1.2; CI 1.0-1.3; p = 0.027; R 2 = 0.16). Current BMI was significantly associated with knee OA but not with hip OA. A high "minimum-BMI" (over the age of 18 years) had the highest odds ratio of all calculated indicators for both osteoarthritis groups. CONCLUSIONS: Based on our findings, it is concluded that the maximum BMI over one's lifespan is a better predictor of OA of the hip or the knee than the current BMI. The knee joint seems to be more sensitive to obesity as current BMI was associated only with knee OA but not with hip OA.


Assuntos
Índice de Massa Corporal , Obesidade/complicações , Osteoartrite do Quadril/etiologia , Osteoartrite do Joelho/etiologia , Idoso , Estudos de Casos e Controles , Feminino , Articulação do Quadril/fisiopatologia , Humanos , Articulação do Joelho/fisiopatologia , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Fatores de Risco , Inquéritos e Questionários
15.
EFORT Open Rev ; 2(5): 189-194, 2017 May.
Artigo em Inglês | MEDLINE | ID: mdl-28698803

RESUMO

Performing sports after total hip arthroplasty (THA) may be associated with a risk of Trauma (fracture and dislocation)Shorter implant survivalThere is no proof that trauma occurs more often than in healthy individuals, but sequelae may be more severe.Shorter implant survival due to repetitive high contact forces is a fact, due to increased wear. The 15 year survival in highly active patients seems to be around 80%.Surgeons can address the needs of active patients by using bearings with low wear rates, and femoral heads up to 36 mm in diameter.The data provided in this review may help to fully inform active patients of the risks. The patient has to balance the pros and cons of sports after THA and to decide the best way for themselves. Cite this article: EFORT Open Rev 2017;2. DOI: 10.1302/2058-5241.2.160059. Originally published online at www.efortopenreviews.org.

16.
Eur J Immunol ; 47(3): 481-492, 2017 03.
Artigo em Inglês | MEDLINE | ID: mdl-27995612

RESUMO

The bone marrow (BM) plays a key role in the long-term maintenance of immunological memory. However, the impact of aging on the production of survival factors for effector/memory T cells and plasma cells in the human BM has not been studied. We now show that the expression of molecules involved in the maintenance of immunological memory in the human BM changes with age. While IL-15, which protects potentially harmful CD8+ CD28- senescent T cells, increases, IL-7 decreases. IL-6, which may synergize with IL-15, is also overexpressed. In contrast, a proliferation-inducing ligand, a plasma cell survival factor, is reduced. IFN-y, TNF, and ROS accumulate in the BM in old age. IL-15 and IL-6 expression are stimulated by IFN-y and correlate with ROS levels in BM mononuclear cells. Both cytokines are reduced by incubation with the ROS scavengers N-acetylcysteine and vitamin C. IL-15 and IL-6 are also overexpressed in the BM of superoxide dismutase 1 knockout mice compared to their WT counterparts. In summary, our results demonstrate the role of inflammation and oxidative stress in age-related changes of immune cell survival factors in the BM, suggesting that antioxidants may be beneficial in counteracting immunosenescence by improving immunological memory in old age.


Assuntos
Envelhecimento/imunologia , Células da Medula Óssea/fisiologia , Linfócitos T CD8-Positivos/fisiologia , Inflamação/imunologia , Superóxido Dismutase-1/metabolismo , Acetilcisteína/farmacologia , Animais , Ácido Ascórbico/farmacologia , Células da Medula Óssea/efeitos dos fármacos , Sobrevivência Celular , Células Cultivadas , Citocinas/metabolismo , Sequestradores de Radicais Livres/farmacologia , Humanos , Memória Imunológica , Imunossenescência , Masculino , Camundongos , Camundongos Endogâmicos C57BL , Camundongos Knockout , Espécies Reativas de Oxigênio/metabolismo , Superóxido Dismutase-1/genética
17.
Prosthet Orthot Int ; 41(4): 373-378, 2017 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-27091864

RESUMO

BACKGROUND: The question whether or not a patient with a hip brace should drive a car is of obvious importance because the advice given to patients to resume driving is often anecdotal as few scientific data are available on this specific subject. OBJECTIVES: To assess driving ability (brake response time) with commonly used hip braces. STUDY DESIGN: Repeated measures design. METHODS: Brake response time was assessed under six conditions: (1) without a brace (control), (2) with a typical postoperative hip brace with adjustable range of motion and the settings: unrestricted, (3) flexion limited to 70°, (4) extension blocked at 20° hip flexion, (5) both flexion and extension limited (20°/70°) and (6) an elastic hip bandage. Brake response time was assessed using a custom-made driving simulator as used in previous studies. The participants were a convenience sample of able-bodied participants. RESULTS: A total of 70 participants (35 women and 35 men) participated in our study. Mean age was 31.1 (standard deviation: 10.6; range: 21.7-66.4) years. A significant within-subject effect for brake response time was found ( p = 0.009), but subsequent post hoc analyses revealed no significant differences between control and the other settings. CONCLUSION: Based on our findings, it does not seem mandatory to recommend driving abstinence for patients wearing a hip orthosis. We suggest that our results be interpreted with caution, because (1) an underlying pathological hip condition needs to be considered, (2) the ability to drive a car safely is multifactorial and brake response time is only one component thereof and (3) brake response time measurements were performed only with healthy participants. Clinical relevance Hip braces are used in the context of joint-preserving and prosthetic surgery of the hip. Therefore, clinicians are confronted with the question whether to allow driving a car with the respective hip brace or not. Our data suggest that hip braces do not impair brake response time.


Assuntos
Condução de Veículo , Braquetes , Quadril , Tempo de Reação/fisiologia , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Amplitude de Movimento Articular , Adulto Jovem
18.
Springerplus ; 5(1): 1414, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27625969

RESUMO

BACKGROUND: The purpose of this study was to investigate the radiological and surgical correlation between preoperative magnetic resonance images (MRI) and the intraoperative findings in patients with acquired adult flatfoot. RESULTS: The overall radiological-surgical correlation between preoperative MRI and the intraoperative findings for posterior tibial tendon insufficiency was only slight to fair in our patient's series. Comparing the most commonly used posterior tibial tendon classification systems, the classification of Rosenberg et al. and Kong et al. showed higher interobserver agreement than our modified classification system and the classification system of Conti et al. CONCLUSION: Further prospective studies are needed to evaluate the importance of preoperative MRI before surgical repair of posterior tibial tendon dysfunction.

19.
Int Orthop ; 40(6): 1261-5, 2016 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-27102606

RESUMO

PURPOSE: Studies on driving safety after lumbar spinal procedures are rare. Previous studies solely reported on a) driving reaction time (DRT) after lumbar nerve root blocks, b) DRT after discectomy and c) preliminary DRT findings after lumbar fusion. METHODS: DRT was assessed with a driving simulator as described before. Measurements were done one day before surgery (preop DRT), one week after surgery (postop1 DRT), three months (postop2 DRT) and one year postoperatively (postop3 DRT). Back pain was determined with visual analogue scales (VAS) on all four occasions. Additionally, we monitored each patient's pre-operative driving frequency and intake of analgesics. For statistical analysis we used an ANOVA for repeated measurements. RESULTS: Thirt eight of 51 patients completed all measurements (17 monosegmental fusion, 14 polysegmental fusion, seven other lumbar fusion procedures). The longitudinal changes in DRT showed overall significance (p = 0.013). Post-hoc tests determined p = 0.035 for the DRT-increase from pre- to postoperative. We did not determine a significant statistical effect for the type of surgery (p = 0.581) or patient age (p = 0.134). A tendency towards statistical significance was ascertained for the influence of patients' driving frequency on DRT (p = 0.051). CONCLUSIONS: We found increased DRT at the time of discharge after lumbar spinal fusion and therefore recommend driving abstinence for the time thereafter. Based on our findings it appears safe to return to driving at 3 months postoperative.


Assuntos
Condução de Veículo/estatística & dados numéricos , Vértebras Lombares/cirurgia , Tempo de Reação , Fusão Vertebral/métodos , Adulto , Idoso , Dor nas Costas/cirurgia , Estudos de Coortes , Discotomia , Feminino , Humanos , Região Lombossacral/cirurgia , Masculino , Pessoa de Meia-Idade , Medição da Dor , Segurança do Paciente , Estudos Prospectivos , Adulto Jovem
20.
Injury ; 46(11): 2278-82, 2015 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-26298020

RESUMO

INTRODUCTION: The question whether or not a patient with an ankle brace should drive a car is of obvious importance because brake response time (BRT) is considered one of the most important factors for driving safety. MATERIALS AND METHODS: Applying a crossover study design, 70 healthy participants (35 women, 35 men) participated in our study. BRT was assessed using a custom-made driving simulator. We assessed BRT under six conditions: without a brace (control) (1), with a typical postoperative ankle brace with adjustable ROM and the settings: unrestricted (2), fixed at 15° (3) plantar flexion, restricted with 15°/50° (4) (dorsal/plantar flexion), a brace for ligament instabilities (5) and an elastic ankle bandage (6). Participants were instructed to apply the brake pedal exclusively with the right foot as quickly as possible on receipt of a visual stimulus. RESULTS: The 70 participants showed significantly impaired BRT with the ankle brace for ROM restriction in the settings: unrestricted (p<0.001), fixed at 15° plantar flexion (p<0.001) and 15°/50° dorsal/plantar flexion (p<0.001) as compared to the control group. BRT was not impaired with the brace for ankle instabilities or the elastic ankle bandage. CONCLUSIONS: In conclusion, right-sided ROM restricting ankle braces involve significant impairment of BRT in healthy participants. No such prolonged BRT was found for an elastic ankle bandage or the ligament brace.


Assuntos
Articulação do Tornozelo/fisiologia , Condução de Veículo , Braquetes/estatística & dados numéricos , Articulação do Joelho/fisiologia , Amplitude de Movimento Articular/fisiologia , Tempo de Reação/fisiologia , Fenômenos Biomecânicos , Simulação por Computador , Estudos Cross-Over , Feminino , Voluntários Saudáveis , Humanos , Masculino
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