RESUMO
Pleural involvement in lymphoma is rare as the initial presentation of disease in the immunocompetent patient. We describe a rare case of primary, isolated pleural B-cell lymphoma in a 75-year-old female, previously treated for adenocarcinoma of the left lung with lobectomy and chemotherapy, who presented with shortness of breath. A CT scan of the chest revealed a right-sided pleural effusion and pleural thickening. She underwent multiple nondiagnostic thoracenteses. A subsequent surgical biopsy was diagnostic of large B-cell lymphoma.
Assuntos
Linfoma de Células B/diagnóstico , Pleura/patologia , Derrame Pleural/etiologia , Idoso , Dispneia/etiologia , Feminino , Humanos , Hospedeiro Imunocomprometido , Pulmão/diagnóstico por imagem , Linfoma de Células B/complicações , Linfoma de Células B/diagnóstico por imagem , Derrame Pleural/diagnóstico por imagem , RadiografiaRESUMO
Solitary neurofibromas are rare tumors associated mainly with neurofibromatosis and widely described in the literature as benign. We report a case of a 55-year-old female with no history of neurofibromatosis who presented with a slow-growing, painless lump on her torso. Pathologic evaluation of the lesion after excisional biopsy revealed high mitotic activity and increased cellularity within the lesion as well as positive S-100 stain. She was diagnosed with solitary subcutaneous neurofibroma with features of malignant peripheral nerve sheath tumor transformation. To our knowledge, no other case of a solitary neurofibroma that transformed into a malignant tumor in this location was described in the literature.
