RESUMO
The efficacy and tolerance of netilmicin administered in a simplified dosage schedule (150 mg BID) were evaluated in an open study of 20 patients with acute systemic infections. Duration of therapy ranged from 6 to 11 days. All isolated causative organisms were eradicated; 85% (17/20) of the patients experienced complete clinical resolution, and the remaining 15% (3/20) experienced definite improvement. No patients developed nephrotoxicity of ototoxicity. The results of this study demonstrate that netilmicin is both effective in the treatment of serious systemic infections and well tolerated when administered at 150 mg twice daily.
Assuntos
Infecções Bacterianas/tratamento farmacológico , Gentamicinas/administração & dosagem , Netilmicina/administração & dosagem , Adolescente , Adulto , Idoso , Infecções Bacterianas/microbiologia , Ensaios Clínicos como Assunto , Feminino , Humanos , Masculino , Pessoa de Meia-IdadeAssuntos
Divertículo Ileal/complicações , Adolescente , Adulto , Criança , Humanos , Masculino , Divertículo Ileal/cirurgia , Pessoa de Meia-IdadeRESUMO
After the surgical treatments in upper abdomen (supramesocolic region) the laboratory parameters frequently point at postoperative pancreatitis. Typical clinical finding is hidden by the primary postoperative disease. Only the complications menifestly point at the existance of pancreas affection. The authors are considering pathogenesis of postoperative pancreatitis, discrepancy about the interpretation of the obtained laboratory parameters, the clinical finding and give a short description of the complication during postoperative pancreatitis, which actually has forced them for the surgical intervention.
