[A new metabolite with fungistatic and bacteriostatic activity, produced by strain L-30 of Flavobacterium sp]. / Novyi metabolit s fungistaticheskoi i bakteriostaticheskoi aktivnost'iu, produtsiruemyi shtammom L-30 Flavobacterium sp.

Flavocin, an agent with fungistatic and bacteriostatic activities, was isolated from the culture of Flavobacterium sp. L-30. The data on the physico-chemical and biological properties of flavocin A, the major active component, are presented. The component was identified with metabolites of the genus Flavobacterium and other genera of nonsporulating bacteria. Flavocin was highly efficient in the treatment of various farm crops. The antagonistic effect of flavocin was observed under field conditions in growing sugar beet, barley, spring wheat, potato and grape. Presowing and nonradical exposure to flavocin lowered the affection of the plants with brown patch, scab, soft rot and oidium.

[The characteristics of alirin B1--the basic component of a fungicidal preparation produced by the Bacillus subtilis 10-VIZR strain]. / Kharakteristika alirina B1--osnovnogo komponenta fungitsidnogo preparata, produtsiruemogo shtammom Bacills subtilis 10-VIZR.

Alirin B1, the major active component of a fungicidal complex produced by Bacillus subtilis 10-VIZR was separated. Its physico-chemical and biological properties as well as the amino acid composition were investigated. Alirin B1 was shown to differ from the polypeptide substances described in the literature. The antibiotic was classified as belonging to the bacteriocins.

[Askostatin--a fungicide from Streptomyces viridovulgaris]. / Askostatin--fungitsid iz Streptomyces viridovulgaris.

Askostatin is a fungicide isolated from the culture of Streptomyces viridovulgaris. It was separated by the countercurrent distribution procedure into components A and B. By the mass and NMR spectra and the biological findings the components were identified with cycloheximide and isocycloheximide respectively.

[Aglycone structure of the polyene antibiotic, gannibamycin]. / Struktura aglikona polienovogo antibiotika gannibamitsina.

Functional analysis of gannibamycin, a new macrolide pentaenic antibiotic was performed. It was found that the antibiotic contained carbonyl, carboxyl group and one molecule of nitrogen and no isolated double bonds. The antibiotic did not participate in the reaction of retroaldol splitting. Ozonization of the antibiotic followed by reduction of the ozonolysis products at first by catalytic hydrogenation and then by lithium aluminohydride resulted in formation of polyols, such as 14-hydroxymethyloctadecanhexaol-1, 6, 13, 15, 17, 18 and 2-methyl-1, 4, 6-trihydroxyoctane. Their structures were proved with mass spectrometry of peracetates. 3-Methyl-tetradecanedicarboxylic acid was isolated from the oxidation products of perhydrogannibamycin. Partial structure of the aglycone, i. e. 1, 30 (or 1, 32)-lactone 13, 15, 17, 30, 32-pentohydroxy-28-methyl-6-ketotetratricontane-18, 20, 22, 24, 26-pentaen-1, 14-dicarboxylic acid was suggested. It was confirmed by the analysis of the mass spectra of the antibiotic permethoxy derivative and its deutero analog.

[Characteristics of a new aromatic heptaenic antibiotic, flavumycin A]. / Kharakteristika novogo aromaticheskogo geptaenovogo antibiotika - flavumitsina A

The study of the products of alkaline and acid hydrolysis showed that flavumycin A included mycosamine, an aminosugar and n-aminoacetophen, an aromatic fragment. The main functional groups of the antibiotics aglicone were determined.

[New heptaene antibiotic, flavomycin, formed by Act. flavus var. geptinicus var. nov]. / Novyi geptaenovyi antibiotik--flavumitsin, obrazuemyi Act. flavus var. geptinicus var. nov

An actinomycetous culture LIA-0734 was isolated from a soil sample. By its morphologo-cultural properties it was close to Act. flavus and differed from the latter in the sporophores, colour of the substrate mycelium on synthetic media amd markedly pronounced antagonism with respect to yeasts and yeast-like fungi. The culture was classified as Act. flavus var. geptinicus var. nov. The actinomycete produced new aromatic heptaens: flavomycins A and B. Their physico-chemical and biological characteristics and singularity are presented.

[Actinomyces fulvoviolaceus ver. achromogenes var. nov., a producer of the new heptaene complex, fulvomycin].

An actinomycetous culture designated as LIA-0721 was isolated from a soil sample. It was close to Act. fulvoviolaceus by its morphologo-cultural features and differed from it in production of melanoid pigments and the spectrum of carbohydrate assimilation. This justified its classification as Act. fulvoviolaceus var. achromogenes var. nov. The culture produced new aromatic heptaens, i. e. fulvomycins A, B and C. Their physico- chemical and biological characteristics are presented.