Immunity in cattle vaccinated against ringworm.

Protective properties of a live, freeze-dried vaccine against ringworm, produced by Bioveta, Ivanovice na Hané, Czechoslovakia, were tested in a group of 422 calves. Vaccinated and control calves were challenged by epicutaneous inoculation of a virulent culture of Trichophyton verrucosum. Between 4.4 and 9.5% of calves challenged between days 14 and 25 after revaccination showed only mild clinical signs of ringworm and 99-100% were fully protected from day 28, the immunity persisting for at least one year. All control calves showed signs of ringworm after challenge. In most cases, extensive mycotic lesions, also penetrating into deep skin layers, were observed. Protective properties of the Czechoslovak vaccine and a USSR vaccine were high and comparable.

[Administration of vaccine against myxomatosis using live MXT by means of external ear puncture with a special needle]. / Aplikace vakcíny proti myxomatóze zivé MXT prupichem usního boltce speciální dvojjehlou.

A new application method was developed and tested for the immunoprophylaxis of rabbits against myxomatosis using a live MXT vaccine. This new application method--injection of the ear with a special double needle--is very simple and easy. Its use enables a five-fold increase in vaccination doses as compared with subcutaneous application while the amount of vaccine remains the same. In laboratory this method with the MXT vaccine secured a 98.2% protection of the vaccinated animals. One vaccination dose contains 18.1 to 37.2 PD50. Eleven months from a single vaccination by injecting the ear, 83% of the rabbits still remained protected against experimental infection. With the use of the new application method of injecting the ear with the special double needle, the live MXT vaccine against myxomatosis in rabbits represents an effective, easily practicable and economically advantageous direction in the immunoprophylaxis of rabbits against myxomatosis.