[The diagnosis and complications of pregnancy in uterine malformation]. / Diagnoza i uslozhneniia na bremennostta pri matochna malformatsiia.

During the period from January 1985 until May 1990, 56 pregnant women with malformed uterus were observed for the clinical curse of pregnancy: 22 women in the first, 26 in the second and 8 in the third trimester. The diagnosis was made by complex investigations: vaginal examination--in 48 cases, ultrasound examination-in 51 cases, previous hysterosalpingography--in 14 cases. In 17 women the performance of a cerclage was needed. In 17 women a hormonal treatment with gravibinon was applied. The results prove the reliability and validity of ultrasound examination, especially through the second trimester of pregnancy and the need of adequate hormonal (gravibinon) and operative treatment (cerclage).

[Our experience with the treatment of Chlamydia trachomatis in acute and chronic inflammatory diseases of the female genitalia]. / Nashiiat opit pri lechenie na Chlamydia trachomatis pri ostri i khronichni vuzpalitelni zaboliavaniia na zhenskite genitalii.

The effect of antibiotic treatment was studied on 41 women with inflammatory gynecological diseases at the acute and chronic stages as the patients were examined for presence of Chlamydia trachomatis in the endocervix. The high frequency of isolated Chlamydia trachomatis in these women (44.1%) with predominance at the age of 21-25 years show the important role of Chlamydia trachomatis in the etiology of the inflammatory process. Possibilities for therapeutic effect by using various antibiotic combinations are discussed.

[Drug treatment of inflammatory postoperative complications]. / Medikamentozno lechenie na vuzpalitelnite sledoperativni uslozhneniia.

PIP: In 1979-1984, 135 women (age unspecified) received drug therapy for various inflammatory diseases following delivery, abortion or gynecological surgery. The group included 36 women who had total hysterectomy and bilateral adnexitis; 11 patients who had total hysterectomy, bilateral adnexitis and resection of the intestine; 24 who had either spontaneous abortion or abortion on demand; 5 who had an illegal abortion; 52 who had cesarean section; 14 who had the forceps delivery or episiotomy; and 4 who had normal delivery (numbers do not add up). Clinical manifestations of postoperative complications could be detected during the early postoperative period. Bacteriological examination of the specimens of wound secretions, cervical secretions and abdominal exudate showed the presence of Escherichia coli, Bacteroides, Streptococcus faecalis, and anaerobic cocci. Anaerobic bacteria accounted for more than 50% of severe inflammatory complications. Anaerobic bacteria played an especially important etiological role in the patients with sepsis after illegal abortion or cesarean section. The patients received antibiotics in accordance with the results of in vitro testing of microbial resistance. Preliminary results of testing were obtained within 48 hours, while the final results were obtained within 4-5 days. The doses and combinations of antibiotics were selected individually, according to the bacteriological diagnosis, severity of the disease, tolerance to antibiotics, and resistance of microorganisms. The most frequently used combination of antibiotics was penicillin (30-80 million units or 100-120 million units in the most severe cases, iv) together with gentamycin (3 x 80, iv) and colimycin (3.04.0). Other frequent combinations were amikacin (4 x 0.5, iv) and cephalosporin (4 x 0.5, iv); and vibramycin (im) or penicillin in combination with clindamycin and colimycin. In addition to antibiotics, the patients received vitamins and hyperbaric oxygenation. Clinical improvement was achieved within 7-14 days.^ieng