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J Microbiol Immunol Infect ; 52(2): 312-319, 2019 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-30472096

RESUMO

BACKGROUND: Genitourinary tuberculosis (GUTB) is rare but fatal if not diagnosed early. The purpose of this study was to investigate the outcomes of GUTB in Taiwan. METHODS: We retrospectively reviewed medical records of 57 patients who were diagnosed as GUTB from January 2002 to December 2016, over a 15-year period. Demographic data and clinical manifestations were recorded for analysis. RESULTS: There were 37 males and 20 females with a median age of 71 years. Kidney (24.6%) was the most involved organ. Fever (56.1%) was the major presentation. Sixteen (28.1%) patients presented unfavorable outcome. Compared with the favorable outcome group, the unfavorable outcome group had more malignancy (p = 0.013), fever (p = 0.020), anemia (p = 0007), thrombocytopenia (p = 0.003), and hypoalbuminemia (p = 0.015). In a multivariate analysis, fever (odds ratio: 42.716, 95% confidence interval: 1.032-1767.569; p = 0.048) was identified as prognostic factors for unfavorable outcome. CONCLUSION: GUTB is often in advanced stages with a high mortality in Taiwan. Establishing a diagnosis is difficult and requires thorough investigation. Fever is associated with unfavorable outcome.


Assuntos
Hospitais de Ensino , Tuberculose Urogenital/tratamento farmacológico , Tuberculose Urogenital/epidemiologia , Tuberculose Urogenital/patologia , Tuberculose Urogenital/fisiopatologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Anemia/epidemiologia , Antituberculosos/farmacologia , Antituberculosos/uso terapêutico , Feminino , Febre/epidemiologia , Humanos , Hipoalbuminemia/epidemiologia , Estimativa de Kaplan-Meier , Nefropatias/epidemiologia , Nefropatias/microbiologia , Modelos Logísticos , Masculino , Testes de Sensibilidade Microbiana , Pessoa de Meia-Idade , Mortalidade , Análise Multivariada , Neoplasias/epidemiologia , Neoplasias/microbiologia , Razão de Chances , Prognóstico , Estudos Retrospectivos , Fatores de Risco , Taiwan/epidemiologia , Trombocitopenia/epidemiologia , Resultado do Tratamento , Sistema Urinário/cirurgia
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