RESUMO
Sera from 3491 pregnant women were screened for the presence of HCV antibodies (anti-HCV). HCV genotyping was also performed on the sera of 94 women. The overall anti-HCV seroprevalence was 3.21%. Anti-HCV seroprevalence was significantly positively correlated with the number of miscarriages. Miscarriage was a significant risk factor for the acquisition of HCV infection from the first miscarriage up to the fifth, the risk increasing with increasing number of miscarriages. A higher proportion of women with a history of miscarriage harboured HCV-1b compared to those with no miscarriage.
Assuntos
Aborto Espontâneo/complicações , Hepatite C/etiologia , Complicações Infecciosas na Gravidez/etiologia , DNA Viral/análise , DNA Viral/genética , Feminino , Genótipo , Hepacivirus/genética , Hepacivirus/imunologia , Hepatite C/sangue , Hepatite C/epidemiologia , Hepatite C/transmissão , Anticorpos Anti-Hepatite C/sangue , Humanos , Iraque/epidemiologia , Modelos Logísticos , Programas de Rastreamento , Vigilância da População , Gravidez , Complicações Infecciosas na Gravidez/sangue , Complicações Infecciosas na Gravidez/epidemiologia , RNA Viral/análise , RNA Viral/genética , Reação em Cadeia da Polimerase Via Transcriptase Reversa , Fatores de Risco , Estudos SoroepidemiológicosRESUMO
Sera from 3491 pregnant women were screened for the presence of HCV antibodies [anti-HCV]. HCV genotyping was also performed on the sera of 94 women. The overall anti-HCV seroprevalence was 3.21%. Anti-HCV seroprevalence was significantly positively correlated with the number of miscarriages. Miscarriage was a significant risk factor for the acquisition of HCV infection from the first miscarriage up to the fifth, the risk increasing with increasing number of miscarriages. A higher proportion of women with a history of miscarriage harboured HCV-1b compared to those with no miscarriage
Assuntos
Aborto Espontâneo , DNA Viral , Anticorpos Anti-Hepatite C , Modelos Logísticos , Gravidez , Complicações Infecciosas na Gravidez , RNA Viral , Estudos Soroepidemiológicos , Hepatite CRESUMO
PIP: Physicians at the School of Medicine at the University of Baghdad in Iraq took a biopsy of endometrial and cervical tissue from women between 25-40 years old before and after using a copper IUD. Researchers exposed each tissue type to autoradiography using 5% methyl tritiated thymidine to indicate active cell metabolism. They also examined each type with an electron microscope. Thymidine uptake fell as duration of a copper IUD was used. For example, 52% of the endometrial and cervical cells were viable before insertion of the copper IUD. After 5 months, thymidine uptake fell remarkably to 32%. It fell to 20% at 12 months, 10% at 18 months, and 6% at 36 months. The thymidine uptake between endometrial and cervical tissue was not statistically different. The major change in the cervix as observed under electron microscopy included a few to a significant number of lymphocytes between the epithelial cells. Apical protrusions remained the same in the secretory cells of the endothelial lining in the endometrium and the glands. In tissues exposed to a copper IUD, the mitochondria of cells in the lumen and glands swelled and the number of lysosomes increased. Further, the number of lymphocytes also increased in both the cervix and endometrium. These results demonstrate the inhibition of mitotic activity in cervical and endometrial cells brought on by a copper IUD, especially during the 1st 2 months. This action could adversely affect a fetus if pregnancy occurs at this time. The researchers suggest that health practitioners advise any pregnant woman who had only recently got a copper IUD to abort the fetus.^ieng
Assuntos
Biologia Celular , Colo do Útero , Técnicas de Laboratório Clínico , Cobre , Endométrio , Histologia , Dispositivos Intrauterinos de Cobre , Ásia , Ásia Ocidental , Biologia , Fenômenos Químicos , Química , Anticoncepção , Países em Desenvolvimento , Diagnóstico , Serviços de Planejamento Familiar , Genitália , Genitália Feminina , Compostos Inorgânicos , Dispositivos Intrauterinos , Iraque , Metais , Oriente Médio , Fisiologia , Sistema Urogenital , ÚteroRESUMO
A total of 889 cord blood samples collected from newborn infants of both sexes and 563 samples of venous blood collected from adult males in Iraq were examined for evidence of glucose-6-phosphate dehydrogenase (G6PD) deficiency. The deficiency was proved to exist in all ethnic groups in Iraq and in both adult males and infants. The overall incidence of the deficiency was 8.9% in the adults and 8.4% in the infants. The difference is not statistically significant. Evidence is given to suggest that favism ("khsaissa") is known to the people of southern Iraq.
