RESUMO
The results of analysis of phospholipids (PL) and fatty acid content in the blood of sheep infected with the nematodes Dictyocaulus filaria are displayed. A significant increase of lysophosphatidylcholine and arachidonic acid as well as a decrease of docozagexaenic acid in PL of infected sheep have been recorded. That points out to structural and functional disorders of cellular membranes during the infection. These disorder could be used as a metabolic criterion to estimate the relationships within the host-parasite system examined.
Assuntos
Dictyocaulus/parasitologia , Eritrócitos/química , Ácidos Graxos/sangue , Fosfolipídeos/sangue , Ovinos/sangue , Animais , Ácido Araquidônico/sangue , Infecções por Dictyocaulus/sangue , Infecções por Dictyocaulus/parasitologia , Ácidos Docosa-Hexaenoicos/sangue , Eritrócitos/metabolismo , Lisofosfatidilcolinas/sangue , Ovinos/parasitologia , Doenças dos Ovinos/sangue , Doenças dos Ovinos/parasitologiaRESUMO
The effect of nematodes Dictyocaulus (D) filaria on phospholipid (PL) composition in the homogenate of sheep lungs has been demonstrated. The comparative analysis has shown no differences in the content and composition of PL in the lungs of healthy sheep and in nematodes. Infection of sheep by helminths was found to result in changes in the PL composition of sheep lungs. Thus, it is possible to conclude that D. filaria affecting structural and functional systems of the host causes changes in its PL content.