1.
Biull Eksp Biol Med
; 108(7): 57-9, 1989 Jul.
Artigo
em Russo
| MEDLINE
| ID: mdl-2804302
RESUMO
The protein C activator detectable in the venom of the Southern Copperhead snake (Agkistrodon contortrix contortrix) was isolated by a combination of chromatofocusing on PBE-94 in the range pH9-7 and gel-filtration on Sephadex G-100 column. The peak protein C activator from Sephadex G-100 column appeared as double diffuse bands with apparent molecular weight of 37,700 and 31,400 after electrophoresis in the presence of sodium dodecylsulfate and 2-mercaptoethanol. The isolated enzyme does not clot human fibrinogen and when mixed with normal plasma generates activity of Protein C. It can be used for the measurement of protein C functional activity.
Assuntos
Venenos de Crotalídeos/análise , Proteína C , Animais , Cromatografia em Gel , Eletroforese em Gel de Poliacrilamida , Ativação Enzimática , Peso Molecular
2.
Ter Arkh
; 55(11): 113-4, 1983.
Artigo
em Russo
| MEDLINE
| ID: mdl-6658649