Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 1 de 1
Filtrar
Mais filtros










Base de dados
Intervalo de ano de publicação
1.
Commun Biol ; 5(1): 566, 2022 06 09.
Artigo em Inglês | MEDLINE | ID: mdl-35681084

RESUMO

Aging is one of the global challenges of our time. The search for new anti-aging interventions is also an issue of great actuality. We report on the success of Drosophila melanogaster lifespan extension under the combined influence of dietary restriction, co-administration of berberine, fucoxanthin, and rapamycin, photodeprivation, and low-temperature conditions up to 185 days in w1118 strain and up to 213 days in long-lived E(z)/w mutants. The trade-off was found between longevity and locomotion. The transcriptome analysis showed an impact of epigenetic alterations, lipid metabolism, cellular respiration, nutrient sensing, immune response, and autophagy in the registered effect.


Assuntos
Drosophila melanogaster , Longevidade , Envelhecimento/fisiologia , Animais , Autofagia , Drosophila melanogaster/genética , Genótipo , Longevidade/genética
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...