[Dynamics of the immunohematologic indices in patients with acute III-IV degree radiation sickness in the post-pancytopenia period]. / Dinamika immunogematologicheskikh pokazatelei u bol'nykh ostroi luchevoi bolezn'iu III-IV stepeni v postpantsitopenicheskii period.

The paper is concerned with the results of determining the total number of lymphocytes, T-lymphocytes and their immunoregulatory subpopulations, B-lymphocyte of peripheral blood, serum IgA, IgG and IgM in 44 patients with ARS, II-IV degree at days 37-109 after the Chernobyl accident. Bone marrow transplantation was performed in all the patients not later than on the 14th day. Among lymphocytes, T-lymphocytes were shown to restore to normal first, the T-helpers/T-suppressors ratio being decreased. In 2 survivors this ratio remained decreased 2 mos. after the normalization of peripheral blood indices. Possibilities of correction of the revealed disorders with immunomodulators were discussed.