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2.
Tsitologiia ; 44(7): 637-42, 2002.
Artigo em Russo | MEDLINE | ID: mdl-12455371

RESUMO

The in vitro induced differentiation of mouse bone marrow stromal cells into nerve cells by retinoic acid and leukemia inhibitory factor has been shown, using morphological, histochemical and immunocytochemical analyses. The developed techniques allow to obtain up to 30% of neural cells in vitro. A suggestion about pluripotency of bone marrow stromal cells and possibility of their application to the cell therapy is discussed.


Assuntos
Células da Medula Óssea/citologia , Neurônios/citologia , Células Estromais/citologia , Animais , Camundongos
3.
Tsitol Genet ; 28(3): 91-2, 3 of cover, 1994.
Artigo em Russo | MEDLINE | ID: mdl-7974793

RESUMO

Mutagenic activities of new gel-forming substances proposed for the use in pharmacy and food industry were studied by the method of scoring mutations in test microorganisms. Sodium carboxy-methyl starch and sodium carboxy-methyl-cellulose did not induce gene mutations in Salmonella typhimurium TA 98 and TA 100.


Assuntos
Carboximetilcelulose Sódica/farmacologia , Aditivos Alimentares/farmacologia , Mutagênicos/farmacologia , Excipientes Farmacêuticos/farmacologia , Amido/análogos & derivados , Relação Dose-Resposta a Droga , Testes de Mutagenicidade , Salmonella typhimurium/efeitos dos fármacos , Salmonella typhimurium/genética , Amido/farmacologia
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