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1.
Aging Clin Exp Res ; 32(8): 1567-1576, 2020 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-31538319

RESUMO

AIM: Swallowing is a vital activity. The difficulty while swallowing, referred to as swallowing disorder, is strongly associated with serious health problems in the elderly. The aim of this study is to enable early recognition of the swallowing function developing as an asymptomatic condition. METHOD: Our study was conducted on elderly populations aged 65 years and over who met the exclusion criteria. Firstly, to be able to reach the number of sampling, "EAT-10 questionnaire", which also has a Turkish validation, was used to eliminate those with symptomatic swallowing disorders. The number of patients we reached was 320, but 7 dropped out of the study and therefore the study was carried out with a total of 313 [reached as 97.8% (up 95% G-power)]. RESULT: We used validated sEMG test in the quantitative (objective) detection of asymptomatic swallowing disorder. In this method, asymptomatic swallowing disorder was detected in 39 cases (12.4%). CONCLUSION: Swallowing disorder without symptoms is frequent and the sEMG test is useful in detecting it in the elderly population.


Assuntos
Doenças Assintomáticas , Transtornos de Deglutição , Eletromiografia , Idoso , Deglutição , Transtornos de Deglutição/diagnóstico , Humanos , Inquéritos e Questionários
2.
Clin Exp Otorhinolaryngol ; 10(4): 296-302, 2017 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-28264555

RESUMO

OBJECTIVES: The aim of this study is to investigate the efficacy of locally applied insulin-like growth factor 1 (IGF-1) on the recovery of facial nerve functions after crush injury in a rabbit model. METHODS: The rabbits were randomly assigned into three groups. Group 1 consisted of the rabbits with crush injury alone; group 2, the animals applied saline solution onto the crushed facial nerve and group 3, IGF-1 implemented to the nerve in the same manner. Facial nerve injury was first electrophysiologically studied on 10th and 42nd days of the procedure. The damage to the facial nerves was then investigated histopathologically, after sacrification of the animals. RESULTS: In the electrophysiological study, compound muscle action potential amplitudes of the crushed nerves in the second group were decreased. In pathological specimens of the first and second groups, the orders of axons were distorted; demyelination and proliferation of Schwann cells were observed. However, in IGF-1 treated group axonal order and myelin were preserved, and Schwann cell proliferation was close to normal (P<0.05). CONCLUSION: Local application of IGF-1 in a slow releasing gel was found efficacious in the recovery of the facial nerve crush injury in rabbits. IGF-1 was considered worthy of being tried in clinical studies in facial nerve injury cases.

3.
Occup Med (Lond) ; 58(3): 212-4, 2008 May.
Artigo em Inglês | MEDLINE | ID: mdl-18211908

RESUMO

AIM: Certain occupations are reported to be associated with a high risk for carpal tunnel syndrome (CTS). In this study, we investigated the development of CTS in iron-steel industry workers. METHODS: Subjects were recruited from a factory of 650 workers and assessed by means of history, physical examination and electrophysiological testing. RESULTS: Seventy-nine subjects from the factory and 53 healthy controls with occupations unrelated to heavy physical work were assessed. None of the worker group had electrophysiological evidence of CTS. One subject in the control group has electrophysiological evidence of CTS. In the worker group, all sensory nerve conduction velocities and ulnar nerve action potential amplitudes in both hands and distal motor latencies were statistically different. CONCLUSIONS: In our study, among a group of heavy labourers, no cases of CTS were detected. However, all electrophysiologic parameters of workers were different from controls. Our results point to a diffuse, but subclinical injury of peripheral nerves under heavy physical work conditions, instead of a local effect such as CTS.


Assuntos
Síndrome do Túnel Carpal/diagnóstico , Indústrias , Doenças Profissionais/diagnóstico , Aço , Potenciais de Ação , Adulto , Estudos de Casos e Controles , Eletrofisiologia , Humanos , Masculino , Doenças do Sistema Nervoso/diagnóstico , Condução Nervosa , Células Receptoras Sensoriais/fisiologia , Turquia , Nervo Ulnar/fisiologia
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