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Curr Med Res Opin ; 21(11): 1717-25, 2005 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-16307691

RESUMO

Cardiovascular disease is increasingly recognised as a consequence of human immunodeficiency virus (HIV) infection in the era of highly active antiretroviral therapy (HAART). Dyslipidaemia is also a feature of HIV infection itself and the antiretroviral drugs from the protease inhibitor classes. Increased rates of atherosclerotic disease and diabetes have been associated with lipodystrophy and now from one of the major causes of morbidity in HIV and acquired immunodeficiency syndrome (AIDS).This review, based on a multi-database keyword search, summarises the lipid changes observed in the course of HIV infection and its treatment, and puts them into the context of other risk factors for cardiac disease, and other causes of cardiovascular disease in HIV.


Assuntos
Doenças Cardiovasculares/etiologia , Infecções por HIV/complicações , Hiperlipidemias/etiologia , Antirretrovirais/efeitos adversos , Antirretrovirais/uso terapêutico , Terapia Antirretroviral de Alta Atividade/efeitos adversos , Glicemia/metabolismo , Infecções por HIV/tratamento farmacológico , Humanos , Lipídeos/fisiologia , Fatores de Risco
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