1.
Org Biomol Chem
; 14(41): 9907-9911, 2016 Oct 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27722419
RESUMO
An operationally simple conversion of aromatic aldehyde hydrazones to monofluoromethylated arenes is reported. The hypervalent iodine reagent TolIF2 serves as an oxidant, converting the hydrazone to the corresponding diazo compounds. The by-product of the oxidation process, HF, is consumed in situ by a denitrogenative hydrofluorination reaction of the diazo group.