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1.
Artif Cells Nanomed Biotechnol ; 43(4): 235-42, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-24393056

RESUMO

Multiwavelength optical capsules can be generated and controlled by using soliton/Gaussian pulses within a nonlinear device system known as a "PANDA" ring circuit and system. The security of molecule/drug transportation can be formed by the strong coupling of soliton-like pulse, where the high-capacity optical capsules can be formed using the multiwavelength solitons, which can be a good advantage and combination of drug delivery to the required targets. Moreover, the multiple access of drug delivery can be formed using the optical networks, which allows the use of various drug molecules with variety of diagnosis and therapeutic applications.


Assuntos
Portadores de Fármacos/química , Modelos Químicos
2.
IEEE Trans Nanobioscience ; 12(3): 222-7, 2013 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-23955778

RESUMO

A generation of optical capsules and tweezers within a modified optical add-drop filter known as PANDA ring resonator with a new concept is proposed. By using dark and bright solitons, the orthogonal tweezers can be formed within the system and observed simultaneously at the output ports. Under the resonant condition, the optical capsules and tweezers generated by dark and bright soliton pair corresponding to the left-hand and right-hand rotating solitons (tweezers) can be generated. When a soliton is interacted by an object, an angular momentum of either bright or dark tweezers is imparted to the object, in which two possible spin states known as tweezer spins are exhibited. Furthermore, an array of molecular capsules and spins, i.e., trapped molecules can be generated and detected by using the proposed system, which can be used to form large scale tweezer or capsule spins. In application, the trapped molecules can be moved and rotated securely to the required destinations, which can be useful for many applications, especially, in medical diagnosis, therapy and surgery.


Assuntos
Nanotecnologia/instrumentação , Pinças Ópticas
3.
Int J Nanomedicine ; 6: 2925-32, 2011.
Artigo em Inglês | MEDLINE | ID: mdl-22131837

RESUMO

BACKGROUND: A novel nanomicro syringe system was proposed for drug storage and delivery using a PANDA ring resonator and atomic buffer. A PANDA ring is a modified optical add/drop filter, named after the well known Chinese bear. In principle, the molecule/drug is trapped by the force generated by different combinations of gradient fields and scattering photons within the PANDA ring. A nanomicro needle system can be formed by optical vortices in the liquid core waveguide which can be embedded on a chip, and can be used for long-term treatment. By using intense optical vortices, the required genes/molecules can be trapped and transported dynamically to the intended destinations via the nanomicro syringe, which is available for drug delivery to target tissues, in particular tumors. The advantage of the proposed system is that by confining the treatment area, the effect can be decreased. The use of different optical vortices for therapeutic efficiency is also discussed.


Assuntos
Sistemas de Liberação de Medicamentos/instrumentação , Terapia de Alvo Molecular/instrumentação , Nanotecnologia/instrumentação , Pinças Ópticas , Animais , Sistemas de Liberação de Medicamentos/métodos , Humanos , Camundongos , Modelos Teóricos , Agulhas , Neoplasias/tratamento farmacológico , Seringas
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