1.
Mol Biosyst
; 8(12): 3103-6, 2012 Oct 30.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23059854
RESUMO
A novel type III polyketide synthase (RePKS) from Rhizobium etli produced a heptaketide pyrone using acetyl-CoA and six molecules of malonyl-CoA. Its catalytic efficiency (k(cat)/K(m) = 5230 mM(-1) min(-1)) for malonyl CoA was found to be the highest ever reported. Molecular dynamics studies revealed the unique features of RePKS.