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1.
BMJ Glob Health ; 7(8)2022 08.
Artigo em Inglês | MEDLINE | ID: mdl-35985695

RESUMO

To address the wide variation in access to cancer care in India requires strengthening of infrastructure, trained oncology workforce, and minimisation of out-of-pocket expenditures. However, even with major investments, it is unlikely to achieve the same level of infrastructure and expertise across the country. Therefore, a resource stratified approach driven by evidence-based and contextualised clinical guidelines is the need of the hour. The National Cancer Grid has been at the forefront of delivery of standardised cancer care through several of its initiatives, including the resource-stratified guidelines. Development of new guidelines is resource and time intensive, which may not be feasible and can delay the implementation. Adaptation of the existing standard guidelines using the transparent and well-documented methodology with involvement of all stakeholders can be one of the most reasonable pathways. However, the adaptation should be done keeping in mind the context, resource availability, budget impact, investment needed for implementation and acceptability by clinicians, patients, policymakers, and other stakeholders. The present paper provides the framework for systematically developing guidelines through adaptation and contextualisation. The process can be used for other health conditions in resource-constraint settings.


Assuntos
Neoplasias , Humanos , Índia , Neoplasias/terapia
2.
Pediatr Hematol Oncol ; 22(3): 199-206, 2005.
Artigo em Inglês | MEDLINE | ID: mdl-16020102

RESUMO

MNTI is an uncommon tumor mainly of infants. Surgery is the primary modality of treatment. Chemotherapy has been tried for recurrent/residual tumors. The chemotherapeutic response of 3 infants treated at a center is discussed here. All 3 infants showed good response to chemotherapy. In 2 of them complete residual tumor resection became possible; 2 of them are alive and tumor regression continues. One child had local recurrence later and was lost for follow-up.


Assuntos
Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Neoplasia Residual/tratamento farmacológico , Tumor Neuroectodérmico Melanótico/tratamento farmacológico , Neoplasias Orbitárias/tratamento farmacológico , Neoplasias Cranianas/tratamento farmacológico , Osso Temporal/patologia , Feminino , Humanos , Lactente , Masculino , Recidiva Local de Neoplasia , Neoplasia Residual/cirurgia , Tumor Neuroectodérmico Melanótico/cirurgia , Neoplasias Orbitárias/cirurgia , Pigmentação , Neoplasias Cranianas/cirurgia , Resultado do Tratamento
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