Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 8 de 8
Filtrar
Mais filtros










Base de dados
Intervalo de ano de publicação
1.
Linacre Q ; 89(2): 178-183, 2022 May.
Artigo em Inglês | MEDLINE | ID: mdl-35619885

RESUMO

Understanding the resource limitations in developing countries, a community health worker (CHW) project was developed to help educate, provide materials, and prevent the spread of COVID-19 in Haiti. CHWs have shown to be an evidence-driven alternative in resource-limited settings. Pwojé Bon Vwazen (The Good Neighbor Project) took place from May 2020 to September 2020 in Port-au-Prince, Haiti. Through the project, 9 CHWs were trained. The project had two coordinators in Haiti. The CHWs, over the period of 4 months, were able to reach 1350 individuals and provide them with education regarding spread and prevention of COVID-19 and distribute materials including soap, hand sanitizers, and masks which were sewn in Haiti. Access to affordable health care presents a unique challenge in resource-limited countries. Training of CHWs and implementation of a CHW program can be an alternative in certain situations.

2.
J Investig Med High Impact Case Rep ; 8: 2324709620982431, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33349046

RESUMO

An 80-year-old male patient presented with sepsis secondary to infected central line which was placed for native aortic valve endocarditis. He also had melena and abdominal pain prior to his presentation. Abdominal computed tomography (CT) was done, which showed cholelithiasis. Esophagogastroduodenoscopy was also done with no source of bleeding identified. Later, he developed hemodynamic instability requiring aggressive fluid resuscitation and multiple packed blood cell transfusions. In view of his hemodynamic instability, a repeat abdominal CT scan showed air droplets within the gallbladder pneumobilia, ascites, diverticulosis, and a bleeding infrahepatic hematoma measuring 6 × 10 cm, which was not on his prior scan 2 days prior. A mesenteric arteriogram was performed that identified an aneurysm of the right hepatic artery with no active bleeding; therefore, it was coiled. Due to his continued clinical decompensation, he underwent an urgent open cholecystectomy, in which serosanguineous fluid, cholecystocolic fistula, and old clot related to his previous bleed were encountered. However, control of bleeding was difficult, and the patient expired. We report this case of right hepatic artery aneurysm that we believe its etiology was related to eroding cholecystitis.


Assuntos
Falso Aneurisma , Colecistite , Idoso de 80 Anos ou mais , Falso Aneurisma/complicações , Falso Aneurisma/diagnóstico por imagem , Hemorragia/etiologia , Artéria Hepática/diagnóstico por imagem , Humanos , Masculino , Tomografia Computadorizada por Raios X
3.
J Investig Med High Impact Case Rep ; 8: 2324709620974208, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33185139

RESUMO

Hemophagocytic lymphohistiocytosis (HLH) is a rare disease that occurs due to unregulated immune system activation induced by various causes including infection and cancer. In this article, we report a case of a 67-year-old male with history of small cell lung cancer who developed HLH triggered by methicillin-resistant Staphylococcus aureus (MRSA) bacteremia. The patient was initially admitted for septic shock and gastrointestinal bleed. Further workup showed that the patient met criteria for HLH diagnosis as he was positive for 5 of the 8 parameters. Unfortunately, the patient's condition worsened and he eventually expired. With this case, we wish to draw attention to the fact that sepsis due to MRSA bacteremia can be a trigger for HLH.


Assuntos
Bacteriemia/complicações , Linfo-Histiocitose Hemofagocítica/etiologia , Staphylococcus aureus Resistente à Meticilina/isolamento & purificação , Choque Séptico/complicações , Idoso , Evolução Fatal , Humanos , Linfo-Histiocitose Hemofagocítica/diagnóstico , Masculino
4.
J Investig Med High Impact Case Rep ; 8: 2324709620966446, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33090049

RESUMO

A 76-year-old Caucasian male with a history of rheumatoid arthritis, Raynaud's phenomenon, pulmonary embolism on warfarin, and a previous amputation of his left partial ring and fifth finger presented with acute onset of rash in bilateral lower extremities. He was recently started on trimethoprim-sulfamethoxazole due to concern for cellulitis. Differential diagnosis for acute-onset rash with the patient's history presented as a challenge to the internist, as the differential is broad. Our case goes through the differential diagnosis to contrast the different presentations of rash in a patient with vasculitis. Ultimately skin biopsy in conjunction with a past positive cryoglobulinemic level helped confirm the diagnosis of cutaneous vasculitis, following which he was started on appropriate treatment and recovered.


Assuntos
Artrite Reumatoide/complicações , Crioglobulinas/metabolismo , Vasculite/complicações , Vasculite/metabolismo , Idoso , Artrite Reumatoide/patologia , Diagnóstico Diferencial , Exantema/patologia , Hospitais Rurais , Humanos , Masculino , Vasculite/patologia
5.
J Investig Med High Impact Case Rep ; 8: 2324709620966863, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33084368

RESUMO

Chronic myelomonocytic leukemia (CMML) is a rare clonal stem cell disorder associated with clinical and pathologic of myelodysplasia and myeloproliferation. Systemic autoimmune/inflammatory disorders (SAID) and polyserositis have been associated with CMML. These manifestations can be observed concomitantly, shortly before diagnosis or anytime along the course of illness. We report a case of myeloproliferative CMML who presented with polyserositis and positive serology for rheumatoid arthritis. Retrospective studies of myelodysplasia/CMML have reported 15% to 25% incidence of SAID. The most commonly observed disorders include systemic vasculitis, connective tissue diseases, polychondritis, seronegative arthritis, and immune thrombocytopenia. SAID does not confer adverse prognosis in retrospective studies. Polyserositis is less common; this may result from leukemic infiltrate or result from autoimmunity. Treatment of serositis includes steroids and cytoreductive agents. Serositis may confer poor prognosis and hypomethylating therapy may improve the outcome.


Assuntos
Artrite Reumatoide/complicações , Leucemia Mielomonocítica Crônica/diagnóstico , Serosite/diagnóstico , Idoso , Autoimunidade , Feminino , Humanos , Leucemia Mielomonocítica Crônica/complicações , Leucemia Mielomonocítica Crônica/tratamento farmacológico , Leucemia Mielomonocítica Crônica/patologia , Serosite/complicações , Serosite/tratamento farmacológico , Serosite/patologia , Esteroides/uso terapêutico
6.
J Investig Med High Impact Case Rep ; 8: 2324709620950128, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32787462

RESUMO

Tick-borne illness has been increasingly on the rise, since the first human case was reported in the late 1980s. Ehrlichia chaffeensis is one of the most common reported causes of tick-borne illness, particularly in the southern states of the United States. The clinical picture presents as a paradigm to the clinician, often missing the diagnosis without an appropriate history being taken and sometimes mistreated for other conditions. With the number of cases on the rise, new manifestations and clinical presentations due to E chaffeensis continue to be reported. Our case report is one such case in a 46-year-old male from Arkansas, with known exposure to multiple tick bites who presented with classical symptoms and laboratory values of tick-borne illness leading to atrial flutter. This unusual manifestation of atrial flutter due to tick-borne illness is rare and poorly understood. Further studies on tick-borne illness due to E chaffeensis may be needed to understand the systemic causes of the bacteria. In addition, in our case report, we bring to attention the standard presentation (symptoms, signs, and laboratory values) of tick-borne illness due to E chaffeensis along with the current standard for diagnosis and treatment.


Assuntos
Flutter Atrial/etiologia , Ehrlichia chaffeensis/isolamento & purificação , Ehrlichiose/diagnóstico , Picadas de Carrapatos/complicações , Animais , Arkansas , Flutter Atrial/diagnóstico , Ehrlichia chaffeensis/genética , Ehrlichiose/transmissão , Eletrocardiografia , Humanos , Masculino , Pessoa de Meia-Idade , Carrapatos/microbiologia
7.
J Investig Med High Impact Case Rep ; 8: 2324709620940492, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32643965

RESUMO

A 28-year-old female presented to the emergency room with epigastric pain, nausea, and vomiting; her lipase was elevated, and computed tomography of abdomen showed evidence of acute pancreatitis. Her past medical history was significant for poorly controlled insulin requiring type 2 diabetes mellitus and 2 previous admissions for hypertriglyceridemia-induced pancreatitis. Due to the severity of her pancreatitis presentation, she was admitted to the intensive care unit. She received aggressive intravenous fluid hydration and was started on an insulin drip. Apheresis was strongly considered given the degree of her hypertriglyceridemia (11 602 mg/dL), but there was no timely access to this treatment option. She, however, significantly improved with insulin therapy alone. Her triglyceride levels decreased rather quickly to 4783 mg/dL within 24 hours and by the fourth day of admission were comfortably <1000 mg/dL with insulin infusion along with clinical improvement. She was discharged on niacin and insulin therapy along with her home medications of statin and fenofibrate.


Assuntos
Hipertrigliceridemia/complicações , Insulina/uso terapêutico , Niacina/uso terapêutico , Pancreatite/tratamento farmacológico , Doença Aguda , Adulto , Diabetes Mellitus Tipo 2/complicações , Diabetes Mellitus Tipo 2/tratamento farmacológico , Feminino , Hospitais Comunitários , Humanos , Hipertrigliceridemia/tratamento farmacológico , Hipertrigliceridemia/fisiopatologia , Hipoglicemiantes/administração & dosagem , Hipoglicemiantes/uso terapêutico , Infusões Intravenosas , Insulina/administração & dosagem , Niacina/administração & dosagem , Pancreatite/etiologia , Pancreatite/fisiopatologia , Índice de Gravidade de Doença
8.
J Investig Med High Impact Case Rep ; 8: 2324709620927872, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32462932

RESUMO

Dyspnea in a HIV patient often warrants an extensive workup. The most common etiology of this presentation is likely due to an infectious etiology. However, with the introduction of antiretroviral treatment, non-AIDS-defining illness including malignancies are increasingly being reported. We report the case of a 46-year-old African American female, nonsmoker who presented with dyspnea and found to have pericardial effusion. In patients with HIV presenting with dyspnea, pericardial effusion should be considered among the differential diagnosis, more so in patients in whom infectious etiologies have been ruled out. Further workup, including imaging and biopsy, revealed that our patient had metastatic lung adenocarcinoma. The introduction of antiretroviral treatment has significantly reduced mortality for those with AIDS from AIDS-defining illness and malignancies. However, the incidence of non-AIDS-defining malignancies like lung adenocarcinoma (most common non-AIDS-defining malignancy) is being increasingly reported. Lung adenocarcinoma often presents at a younger age in patients with HIV than the general population. Smoking rates are higher in patients with HIV and may be a contributing factor to the early onset of lung cancer; however, other factors such as long-term medications and immunomodulation in HIV may also play a role. Prognosis is also worse for HIV-positive patients having lung cancer compared with those who are HIV negative, even at a similar stage of cancer.


Assuntos
Adenocarcinoma de Pulmão/diagnóstico , Dispneia/etiologia , Infecções por HIV/complicações , Neoplasias Pulmonares/diagnóstico , Derrame Pericárdico/etiologia , Adenocarcinoma de Pulmão/virologia , Antirretrovirais/uso terapêutico , Feminino , Infecções por HIV/tratamento farmacológico , Humanos , Neoplasias Pulmonares/virologia , Pessoa de Meia-Idade
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...