Distress intolerance in the parents of substance dependent patients.

The purpose of this study was to determine levels of Distress Tolerance (DT) and to compare levels of DT, depression, and anxiety in the parents of substance dependent patients. This sample included 40 parents of inpatients undergoing treatment for substance dependence (SDPP) in the Balikli Rum Hospital, Istanbul, Turkey. A healthy control group was recruited of 40 individuals with no Axis I diagnoses that were counterbalanced with the SDPP group in terms of age and sex. All study participants completed a sociodemographic data form and the Beck Depression Inventory, the Beck Anxiety Inventory, the State & Trait Anxiety Inventory, and the Distress Tolerance Scale. DSM-IV-TR Axis I diagnoses were evaluated by psychiatrists through face to face interviews in which a Structured Clinical Interview (SCID I) was administered. We found a statistically significant lower level of distress tolerance (DT) in our SDPP group. A negative relationship was found between levels of DT, depression and anxiety. The results of our study suggested that negative emotional symptoms such as depression, anxiety, and distress tolerance were frequently seen in parents of substance dependent patients. Limitations and future research directions are also discussed.

General health status and intelligence scores of children of mothers with acromegaly do not differ from those of healthy mothers.

PURPOSE: To determine the physical status and intelligence scores of children of acromegalic mothers and to compare them with those of children from mothers without acromegaly. METHODS: Six women with acromegaly who became pregnant under follow-up between 2010 and 2014 and their 16 children (group A) were assessed and compared with 16 children of healthy women (group B) and 15 children of women with prolactinoma (group C). The physical examinations of children were performed by the department of pediatric endocrinology and intelligence quotient (IQ) testing was undertaken by adult and pediatric psychiatry departments, using appropriate scales for their ages. RESULTS: Six of the 16 children (girls/boys: 7/9) were born after the diagnosis of acromegaly. Five of the 6 pregnancies occured when the patients were taking somatostatin analogs, none continued taking the drugs during pregnancy. The mean IQ of groups A, B, and C were 106.4 ± 12.5, 105.3 ± 12.5, and 103.2 ± 16.1 respectively (p > 0.05). The mean ages, birth percentiles, recent weight and height standard deviation scores were similar between groups (p > 0.05). Two siblings from group A and 1 child from group B were large for gestational age at birth. At recent follow-up, two children from group A were found tall for their age and one from group C was short for his age and was placed under the care of pediatric endocrinology clinic. CONCLUSIONS: Pregnancies in acromegaly seems to be uneventful and the general health status and IQ scores of children from women with and without acromegaly were found similar.