[The use of acetylcysteine in the combined treatment of patients with acute 1,2-dichloroethane poisoning]. / Primenenie atsetiltsisteina v kompleksnom lechenii bol'nykh s ostrym otravleniem 1,2-dikhlorétanom.

The authors analyse the use of acetylcysteine as specific antidote treatment in 37 patients with acute 1,2-dichlorethane (DCE) poisoning. Administration of dichlorethane did not produce any determining effect on the outcome of the treatment in critical and irreversible concentration of DCE in the blood. The main component in complex therapy is early hemosorption. Acetylcystein may be used in the complex treatment of acute DCE intoxications after early extracorporal detoxication with the purpose of reducing the severity of troxic of hepatopathies.

[Hemosorption in the combined treatment of patients with acute exogenous poisonings]. / Gemosorbtsiia v kompleksnom lechenii bol'nykh s ostrymi ékzogennymi otravleniiami.

The authors analyze their experience with 247 hemosorptions in 163 patients with acute exogenous poisonings. Indications and contraindications to hemosorption in these patients are described. Methodical aspects of hemosorption are described: vascular approaches, apparatus, prehemosorption care, regimens of hemosorption. Hemosorption may be associated with hemodialysis, hemofiltration, ultraviolet irradiation of the blood.

[Tactics and emergency aid in acute chemical poisoning]. / Taktika i neotlozhnaia pomoshch' pri ostrykh khimicheskikh otravleniiakh.

Successful treatment of acute intoxications should include early urgent measures, use of specific antidotes, polysymptomatic and polysyndromic treatment. It is an error to delay intensive care until laboratory identification of the toxicant. Only combined use of methods directed to potentiate natural urocesses, intra--and extracorporal detoxication allows to improve treatment results of treating acute intoxications.

[Hemosorption in the combined treatment of acute 1,2-dichloroethane poisonings]. / Gemosorbtsiia v kompleksnom lechenii ostrykh otravlenii 1,2-dikhlorétanom.

Carbon hemosorption was carried out in 41 patients suffering of 1,2-dichlorethane intoxication (acute). Complex methods of therapy included also methods of potentiation of natural processes of detoxication, enterosorption, specific antidote treatment with acetylcysteine and vitamin E. Use of hemosorption favoured essential reduction of lethality, decrease of the number of severe complications (exotoxic shock, hepatopathy).

[Cholinesterase reactivators in the combined treatment of patients with acute organophosphate insecticide poisonings]. / Reaktivatory kholinésterazy v kompleksnom lechenii bol'nykh s ostrymi otravleniiami fosfororganicheskimi insektitsidami.

The efficacy of different cholinesterase reactivators (alloxyme, dietixyme, dipiroxyme, isonitrosine) used as specific antidotes) was evaluated in 78 patients with acute intoxications by phosphorus-organic insecticides. The most pronounced clinical effect was obtained with use of alloxyme and dietixyme. The number of side-effects was observed during employment of dietixyme. Use of dipiroxyme with isonitrosine was less effective and was connected with a higher number of side-effects.

[Ways to improve the results of the treatment of acute obstruction of the aorta and major arteries of the lower extremities in middle-aged and elderly patients]. / Puti uluchsheniia rezul'tatov lecheniia ostroi neprokhodimosti aorty i magistral'nykh arterii konechnostei u bol'nykh pozhilogo i starcheskogo vozrasta.

The authors treated acute arterial obstruction in 190 patients. A complex of diagnostic and therapeutic measures, including the establishment of indications for operative treatment, development of tactics, use of ++physico-technical methods (ultrasound study, rheography, electrocardiography, ++roentgeno-contrast angiography, ultra-violet blood irradiation, electromyostimulation) was developed. A positive result of treatment was obtained in 78.9% of patients, incidence of an amputation performance was 13.7% lethality--12.6%.

[Comparative characteristics of the variants of vascular approach during performing hemosorption in patients with acute poisoning]. / Sravnitel'naia kharakteristika variantov sosudistogo dostupa pri vypolnenii gemosorbtsii u bolnykh s ostrymi otravleniiami.

In performance of hemosorption in 108 patients with acute intoxications, 210 manipulations of Seldinger's central venous puncture and catheterization, Skribner's arteriovenous shunting, section of the basal brachial vein were accomplished. In 23 (10.1%) patients, the complications developed: hematoma at the site of puncture--in 10, puncture of the subclavian artery--in 3, puncture of the femoral artery--in 6, shunt thrombosis--in 2, catheter thrombosis--in 2. In patients with acute intoxications, the use of veno-venous method of hemosorption with Seldinger's catheterization of the subclavian and femoral veins is preferrable.

[The role of hemodialysis and hemosorption in the complex therapy of acute poisoning]. / Rol' gemodializa i gemosorbtsii v kompleksnoi terapii ostrykh otravlenii.

The method of henosorption and hemodialysis was used in 50 patients with acute intoxication. A total of 44 hemosorption and 40 hemodialysis procedures were carried out in the toxicogenous and somatogenous stage of acute intoxication. Results indicate high efficacy of using extracorporal detoxication in the toxicogenous stage of acute poisoning. The method of treatment of acute chemical intoxications is described.